Development of the optimal scheme for the synthesis of the dipeptide TSPO ligand, N-phenylpropionyl-L-tryptophanyl-L-leucine amide (GD-102), a potential anxiolytic drug
Previously at the Zakusov Research Institute of Pharmacology the first dipeptide ligand TSPO, the compound N-phenylpropionyl-L-tryptophanyl-L-leucine amide (laboratory code GD-102), was designed and synthesized. The anxiolytic activity was detected for this compound at the doses 0.01–1.0 mg/kg intra...
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| Главный автор: | |
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| Формат: | Статья |
| Язык: | русский |
| Опубликовано: |
LLC “Publisher OKI”
2024-01-01
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| Серии: | Фармакокинетика и Фармакодинамика |
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| Online-ссылка: | https://www.pharmacokinetica.ru/jour/article/view/396 |
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