Protective effect of micheliolide against inflammation and oxidative stress in asthma through the MAPK/NF-κB signalling pathway

Protective effect of micheliolide against inflammation and oxidative stress in asthma through the MAPK/NF-κB signalling pathway

Background: Asthma involves oxidative stress imbalance and activation of the NLRP3 inflammasome. Micheliolide (MCL), a sesquiterpene lactone compound, has promising anti-inflammatory properties. However, its therapeutic potential in asthma remains unexplored. Objective: We aimed to investigate the t...

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Bibliographic Details
Main Authors: Jia Wang, Dan Han, Lina Han, Qinzhen Zhang, Shaozhuang Liu, Jiapeng Hu, Yunxiao Shang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:World Allergy Organization Journal
Subjects:
Asthma
Micheliolide
Inflammation
Oxidative stress
NLRP3
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455125000687
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http://www.sciencedirect.com/science/article/pii/S1939455125000687

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