MiR-221, miR-320a, miR133a, and miR-133b as potential biomarkers in leiomyosarcoma

BackgroundLeiomyosarcoma is an aggressive tumor with a high rate of distant metastasis and poor prognosis. No standardized biomarkers are available to assess early diagnosis or monitoring during the clinical course. MicroRNAs (miRNAs) function in modulating a multitude of targets and are involved in...

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Main Authors: Mst Nasrin Akhtar, Annabell Walter, Kathrin Katenkamp, Yuan Chen, Thomas Lehmann, Wolfram Weschenfelder, Christian Spiegel, Matthias Vogt, Gunther O. Hofmann, Andreas Hochhaus, Nikolaus Gaßler, Joachim H. Clement, Karin G. Schrenk
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1577859/full
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