Synthesis and cytotoxic activity investigations of DNA-tropic 4-dimethylaminostyryl derivatives of N-methyl-pyrimidobenzimidazolium iodides
Introduction. The creation of new compounds with pronounced cytotoxic activity is one of the priority goals in modern medicinal chemistry due to the emergence of multidrug resistance (MDR) to existing chemotherapy drugs for many types of tumour diseases.The objective was the synthesis of DNA-tropic...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Academician I.P. Pavlov First St. Petersburg State Medical University
2024-12-01
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| Series: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
| Subjects: | |
| Online Access: | https://www.sci-notes.ru/jour/article/view/1079 |
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