Treg cell plasticity as a driver of inflammation in spondyloarthritis and psoriasis

Treg cell plasticity as a driver of inflammation in spondyloarthritis and psoriasis

Regulatory T cells (Tregs) are critical for maintaining immune tolerance by suppressing effector T cell responses. However, in chronic inflammatory diseases such as spondyloarthritis (SpA) and psoriasis (PsO), Tregs can lose their stability and acquire pro-inflammatory characteristics, a phenomenon...

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Bibliographic Details
Main Authors: Ingrid Itzayanna Ortega-Mejia, Nayeli Romero-López, Julio César Casasola-Vargas, Rubén Burgos-Vargas, María Lilia Domínguez-López, José Pablo Romero-López
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
Treg cells
Treg plasticity
IL-17
spondyloarthritis
psoriasis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1621396/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1621396/full

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