IMMUNE CHECKPOINT INHIBITION AND AUTOIMMUNITY: RHEUMATOLOGICAL PROBLEMS
The paper deals with the mechanisms of a T-cell immune response, which depends on the balance between costimulatory and coinhibitory signals that have been called as immune checkpoints (ICP). The imbalance of T-cell activation within ICTs (CTLA4/CD28 and PD1/PD1L) is considered to be a fundamental m...
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| Main Author: | |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA PRESS LLC
2018-03-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/2492 |
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