Characteristics of stem sings of EpCAM-negative and EpCAM-positive tumor cells in primary tumor and 2D and 3D cultures in breast cancer

One of the predictors of adverse prognosis in breast cancer is the overexpression of the EpCAM protein. However, a signifcant part of tumor cells have low or no EpCAM expression. The molecular features and the ability to grow in 2D and 3D cultures, indirectly refecting metastatic potential of tumor...

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Main Authors: V. V. Alifanov, M. S. Tretyakova, E. S. Grigoryeva, M. A. Buldakov, L. A. Tashireva, E. S. Kolegova, E. S. Andryuhova, M. V. Zavyalova, E. V. Denisov, N. V. Cherdyntseva, V. M. Perelmuter
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2024-11-01
Series:Сибирский онкологический журнал
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Online Access:https://www.siboncoj.ru/jour/article/view/3269
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