Research on Measurement Conditions for Obtaining Significant, Stable, and Repeatable SERS Signal of Human Blood Serum

The Raman spectra of human blood serum can be used to identify cancer or other diseases; however, obtaining a reliable surface enhanced Raman scattering (SERS) signal of human blood serum is difficult. Two primary factors that affect SERS measurement of serum are photodegradation and sample composit...

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Main Authors: Huaizhou Jin, Qipeng Lu, Shangzhong Jin, Zhengbo Song, Yanqiu Zou, Haiquan Ding, Hongzhi Gao, Xingdan Chen
Format: Article
Language:English
Published: IEEE 2017-01-01
Series:IEEE Photonics Journal
Subjects:
Online Access:https://ieeexplore.ieee.org/document/7865959/
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author Huaizhou Jin
Qipeng Lu
Shangzhong Jin
Zhengbo Song
Yanqiu Zou
Haiquan Ding
Hongzhi Gao
Xingdan Chen
author_facet Huaizhou Jin
Qipeng Lu
Shangzhong Jin
Zhengbo Song
Yanqiu Zou
Haiquan Ding
Hongzhi Gao
Xingdan Chen
author_sort Huaizhou Jin
collection DOAJ
description The Raman spectra of human blood serum can be used to identify cancer or other diseases; however, obtaining a reliable surface enhanced Raman scattering (SERS) signal of human blood serum is difficult. Two primary factors that affect SERS measurement of serum are photodegradation and sample composition, which are investigated in this research. In the end, this research proposes a promising set of measurement conditions that can both acquire reliable serum Raman signals and avoid photodegradation.
format Article
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language English
publishDate 2017-01-01
publisher IEEE
record_format Article
series IEEE Photonics Journal
spelling doaj-art-0b6016eb1e9743c883edeaefb972297f2025-07-01T23:18:26ZengIEEEIEEE Photonics Journal1943-06552017-01-019211010.1109/JPHOT.2017.26729007865959Research on Measurement Conditions for Obtaining Significant, Stable, and Repeatable SERS Signal of Human Blood SerumHuaizhou Jin0Qipeng Lu1Shangzhong Jin2Zhengbo Song3Yanqiu Zou4Haiquan Ding5Hongzhi Gao6Xingdan Chen7State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, ChinaState Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, ChinaKey Laboratory of Zhejiang Province on Modern Measurement Technology and Instruments, China Jiliang University, Hangzhou, ChinaZhejiang Cancer Hospital, Hangzhou, ChinaKey Laboratory of Zhejiang Province on Modern Measurement Technology and Instruments, China Jiliang University, Hangzhou, ChinaState Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, ChinaState Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, ChinaState Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, ChinaThe Raman spectra of human blood serum can be used to identify cancer or other diseases; however, obtaining a reliable surface enhanced Raman scattering (SERS) signal of human blood serum is difficult. Two primary factors that affect SERS measurement of serum are photodegradation and sample composition, which are investigated in this research. In the end, this research proposes a promising set of measurement conditions that can both acquire reliable serum Raman signals and avoid photodegradation.https://ieeexplore.ieee.org/document/7865959/Raman spectroscopyblood monitoringoptical diagnostics for medicineoptical standards and testing.
spellingShingle Huaizhou Jin
Qipeng Lu
Shangzhong Jin
Zhengbo Song
Yanqiu Zou
Haiquan Ding
Hongzhi Gao
Xingdan Chen
Research on Measurement Conditions for Obtaining Significant, Stable, and Repeatable SERS Signal of Human Blood Serum
IEEE Photonics Journal
Raman spectroscopy
blood monitoring
optical diagnostics for medicine
optical standards and testing.
title Research on Measurement Conditions for Obtaining Significant, Stable, and Repeatable SERS Signal of Human Blood Serum
title_full Research on Measurement Conditions for Obtaining Significant, Stable, and Repeatable SERS Signal of Human Blood Serum
title_fullStr Research on Measurement Conditions for Obtaining Significant, Stable, and Repeatable SERS Signal of Human Blood Serum
title_full_unstemmed Research on Measurement Conditions for Obtaining Significant, Stable, and Repeatable SERS Signal of Human Blood Serum
title_short Research on Measurement Conditions for Obtaining Significant, Stable, and Repeatable SERS Signal of Human Blood Serum
title_sort research on measurement conditions for obtaining significant stable and repeatable sers signal of human blood serum
topic Raman spectroscopy
blood monitoring
optical diagnostics for medicine
optical standards and testing.
url https://ieeexplore.ieee.org/document/7865959/
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