Granulysin-high decidual NK cells in macaques and humans share signatures of immune defense

Granulysin-high decidual NK cells in macaques and humans share signatures of immune defense

Summary: Decidual natural killer cells (dNKs) are key immune effector cells at the maternal-fetal interface. dNKs utilize the antimicrobial peptide granulysin (GNLY) to kill bacteria without killing infected trophoblasts. Since rodents lack the GNLY gene, the in vivo biology of GNLY expression by dN...

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Main Authors: Nina Salinger Prasanphanich, Giulia Protti, Monica Cappelletti, Feiyang Ma, Neema Pithia, Angel Dasenbrock, Jerzy Stanek, Claire A. Chougnet, Suhas G. Kallapur, Matteo Pellegrini, Tamara Tilburgs, Pietro Presicce
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
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CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725007144
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http://www.sciencedirect.com/science/article/pii/S2211124725007144

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