Systems biology approaches investigating mitochondrial dysfunction in cyanotic heart disease: a systematic reviewResearch in context

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Systems biology approaches investigating mitochondrial dysfunction in cyanotic heart disease: a systematic reviewResearch in context

Summary: Background: Cyanotic congenital heart disease (CCHD) affects over 3 million individuals globally and can progress to heart failure. Mitochondrial dysfunction is well established in adult heart failure and is also a central feature of CCHD. CCHD cyanosis itself contributes to further mitoch...

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Main Authors:	Malak Elbatarny, Yu Tong Lu, Mostin Hu, John Coles, Seema Mital, Amanda Ross-White, Osami Honjo, David J. Barron, Anthony O. Gramolini
Format:	Article
Language:	English
Published:	Elsevier 2025-08-01
Series:	EBioMedicine
Subjects:	Systems biology Mitochondria Cyanotic congenital heart disease Multi-omics Bioinformatics
Online Access:	http://www.sciencedirect.com/science/article/pii/S235239642500283X
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