Novel 3-Methyl-1,6-Diazaphenothiazine as an Anticancer Agent—Synthesis, Structure, and In Vitro Anticancer Evaluation

Novel 3-Methyl-1,6-Diazaphenothiazine as an Anticancer Agent—Synthesis, Structure, and In Vitro Anticancer Evaluation

Pyridine derivatives are widely distributed in nature and have valuable pharmacological properties. The pyridine core can be found in drugs such as sorafenib, zapiclone or prothipendyl. Dipyridothiazines are derivatives of phenothiazines that exhibit valuable anticancer, antioxidant and immunomodula...

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Main Authors: Beata Morak-Młodawska, Emilia Martula, Małgorzata Jeleń, Artur Beberok, Zuzanna Rzepka, Sebastian Musiał, Szymon Małek, Marta Karkoszka-Stanowska, Dorota Wrześniok
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
pyridine derivatives
dipyridothiazines
cytotoxicity
melanoma
apoptosis detection
Online Access:https://www.mdpi.com/1420-3049/30/13/2779
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