Ethical Principles for Handling Laboratory Animals in an Experiment with Pathogenic Biological Agents of the I-II Groups
Current international and major part of national documents, regulating experiments on laboratory animals, is set out in Bioethics Convention 3”R”. Presently this 3”R” principle is still relevant and commonly accepted global standard. Objective of the study was to verify the compliance of the staff a...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2018-12-01
|
| Series: | Проблемы особо опасных инфекций |
| Subjects: | |
| Online Access: | https://journal.microbe.ru/jour/article/view/1085 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839636848249405440 |
|---|---|
| author | V. G. Germanchuk A. P. Semakova N. Yu. Shavina |
| author_facet | V. G. Germanchuk A. P. Semakova N. Yu. Shavina |
| author_sort | V. G. Germanchuk |
| collection | DOAJ |
| description | Current international and major part of national documents, regulating experiments on laboratory animals, is set out in Bioethics Convention 3”R”. Presently this 3”R” principle is still relevant and commonly accepted global standard. Objective of the study was to verify the compliance of the staff at the institute with the ethical principles of biological safety when handling laboratory animals infected with pathogenic biological agents (PBA) of the I-II groups, performing diagnostic, experimental, and manufacturing activities. Results and discussion. Carried out analysis of ethical principle implementation, when working with biomodels infected with pathogenic biological agents of the I-II groups, performing scientific and manufacturing activities shows that operational procedures comply with the requirements of biological safety and regulations of ethical code, as well as international standards for humane treatment to animals in biomedical investigations. Conclusions. The work with laboratory animals infected with PBA of the I-II groups at the premises of RusRAPI “Microbe” meets the requirements of biological safety and norms of ethical code. Experiments on animals are aimed at obtainment of new scientific knowledge, preservation and improvement of human health, and also monitoring of natural foci of particularly dangerous infections following the rules of 3“R” bioethical concept. |
| format | Article |
| id | doaj-art-09be92c07e004c2d9977b10b51b9c48d |
| institution | Matheson Library |
| issn | 0370-1069 2658-719X |
| language | Russian |
| publishDate | 2018-12-01 |
| publisher | Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” |
| record_format | Article |
| series | Проблемы особо опасных инфекций |
| spelling | doaj-art-09be92c07e004c2d9977b10b51b9c48d2025-07-07T08:02:41ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2018-12-0104333810.21055/0370-1069-2018-4-33-381068Ethical Principles for Handling Laboratory Animals in an Experiment with Pathogenic Biological Agents of the I-II GroupsV. G. Germanchuk0A. P. Semakova1N. Yu. Shavina2Russian Research Anti-Plague Institute "Microbe"Russian Research Anti-Plague Institute "Microbe"Russian Research Anti-Plague Institute "Microbe"Current international and major part of national documents, regulating experiments on laboratory animals, is set out in Bioethics Convention 3”R”. Presently this 3”R” principle is still relevant and commonly accepted global standard. Objective of the study was to verify the compliance of the staff at the institute with the ethical principles of biological safety when handling laboratory animals infected with pathogenic biological agents (PBA) of the I-II groups, performing diagnostic, experimental, and manufacturing activities. Results and discussion. Carried out analysis of ethical principle implementation, when working with biomodels infected with pathogenic biological agents of the I-II groups, performing scientific and manufacturing activities shows that operational procedures comply with the requirements of biological safety and regulations of ethical code, as well as international standards for humane treatment to animals in biomedical investigations. Conclusions. The work with laboratory animals infected with PBA of the I-II groups at the premises of RusRAPI “Microbe” meets the requirements of biological safety and norms of ethical code. Experiments on animals are aimed at obtainment of new scientific knowledge, preservation and improvement of human health, and also monitoring of natural foci of particularly dangerous infections following the rules of 3“R” bioethical concept.https://journal.microbe.ru/jour/article/view/1085ethical principlesbiological safetypathogenic biological agents of i-ii groupslaboratory animals |
| spellingShingle | V. G. Germanchuk A. P. Semakova N. Yu. Shavina Ethical Principles for Handling Laboratory Animals in an Experiment with Pathogenic Biological Agents of the I-II Groups Проблемы особо опасных инфекций ethical principles biological safety pathogenic biological agents of i-ii groups laboratory animals |
| title | Ethical Principles for Handling Laboratory Animals in an Experiment with Pathogenic Biological Agents of the I-II Groups |
| title_full | Ethical Principles for Handling Laboratory Animals in an Experiment with Pathogenic Biological Agents of the I-II Groups |
| title_fullStr | Ethical Principles for Handling Laboratory Animals in an Experiment with Pathogenic Biological Agents of the I-II Groups |
| title_full_unstemmed | Ethical Principles for Handling Laboratory Animals in an Experiment with Pathogenic Biological Agents of the I-II Groups |
| title_short | Ethical Principles for Handling Laboratory Animals in an Experiment with Pathogenic Biological Agents of the I-II Groups |
| title_sort | ethical principles for handling laboratory animals in an experiment with pathogenic biological agents of the i ii groups |
| topic | ethical principles biological safety pathogenic biological agents of i-ii groups laboratory animals |
| url | https://journal.microbe.ru/jour/article/view/1085 |
| work_keys_str_mv | AT vggermanchuk ethicalprinciplesforhandlinglaboratoryanimalsinanexperimentwithpathogenicbiologicalagentsoftheiiigroups AT apsemakova ethicalprinciplesforhandlinglaboratoryanimalsinanexperimentwithpathogenicbiologicalagentsoftheiiigroups AT nyushavina ethicalprinciplesforhandlinglaboratoryanimalsinanexperimentwithpathogenicbiologicalagentsoftheiiigroups |