Alpha-Synuclein Seed Amplification Assays in Parkinson’s Disease: A Systematic Review and Network Meta-Analysis

QR Code

Alpha-Synuclein Seed Amplification Assays in Parkinson’s Disease: A Systematic Review and Network Meta-Analysis

Introduction and objective: Assessment of α-synuclein (αSyn) seed amplification assays (αSyn-SAA) accuracy in distinguishing Parkinson’s disease (PD) from controls using cerebrospinal fluid (CSF), blood, skin, extracellular vesicles (ECV), saliva, olfactory mucosa (OM), gastrointestinal tract (GIT),...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jamir Pitton Rissardo, Ana Leticia Fornari Caprara
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Clinics and Practice
Subjects:	alpha-synuclein synucleinopathy biomarker biofluid protein misfolding cyclic amplification (PMCA) real-time quaking-induced conversion (RT-QuIC)
Online Access:	https://www.mdpi.com/2039-7283/15/6/107
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

RT-QuIC optimization for prion detection in soils
by: Madeline K. Grunklee, et al.
Published: (2025-06-01)

quicR: An R library for streamlined data handling of real-time quaking induced conversion assays
by: Gage R. Rowden, et al.
Published: (2025-09-01)

Addressing chronic wasting disease in Korean farms: topsoil removal and 2N NaOH treatment before cervid restocking
by: Kyung-Je Park, et al.
Published: (2025-12-01)

Alpha-Synuclein Dysregulation in Systemic Pathophysiology of Synucleinopathies
by: Hallie H. Dolin, et al.
Published: (2025-07-01)

Abnormal α-synuclein binds to synaptotagmin 13, impairing extracellular vesicle release in synucleinopathies
by: Yasuo Miki, et al.
Published: (2025-06-01)

Subtle concentration changes in zinc hold the key to fibrillation of α-synuclein: an updated insight on the micronutrient’s role in prevention of neurodegenerative disorders
by: Samudra Prosad Banik, et al.
Published: (2025-07-01)

Alpha-synuclein in cutaneous small nerve fibers
by: Siepmann T, et al.
Published: (2016-10-01)

Development of Positron Emission Tomography Radiotracers for Imaging α-Synuclein Aggregates
by: Xiaodi Guo, et al.
Published: (2025-06-01)

c-Abl Inhibitors in Parkinson’s: Exploring Hypotheses on Alpha-Synuclein Modulation
by: Jyutia Nargish, et al.
Published: (2025-04-01)

Neuromodulation influences T lymphocyte calcium signaling and alpha synuclein clearance: implications for Parkinson’s disease
by: Alysia Ross, et al.
Published: (2025-07-01)

Earth quake engineering in Britain : proceedings of an conference organized by the Institution of Civil Engineers and the Society of Earthquake and Civil Engineering Dynamics, held at the University of East Anglia, 18-19 April 1985.
Published: (1985)

Detection of hyperphosphorylated tau protein and &alpha;-synuclein in spinal cord of patients with Alzheimer&rsquo;s disease
by: Guo Y, et al.
Published: (2016-02-01)

Analytical Evaluation of the WebSocket and WebTransport Protocols for the Class of SCADA Systems Operating Within the Intranet
by: G. A. Zvonareva, et al.
Published: (2024-11-01)

Accumulation of aggregated alpha-synuclein in neural tissue structures in neurodegenerative diseases
by: V. N. Salkov, et al.
Published: (2024-01-01)

A novel stable transgenic zebrafish line expressing mCherry-tagged human alpha-synuclein in the nervous system and exhibiting all the key features of Lewy body disorders at larval stage
by: Silvia Zini, et al.
Published: (2025-09-01)

Modified QuEChERS for antiepileptic drugs detection in forensic toxicology
by: Ahmad Shekari, et al.
Published: (2025-06-01)

Neurobiology of Dystonia: Review of Genetics, Animal Models, and Neuroimaging
by: Jamir Pitton Rissardo, et al.
Published: (2025-07-01)

Quantification of lactate enantiomers in human sweat samples using two-dimensional liquid chromatography
by: Kazushi Mori, et al.
Published: (2025-11-01)

Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity
by: Carlos M. Díaz-Domínguez, et al.
Published: (2025-09-01)

Trans-sodium crocetinate ameliorates Parkinson-like disease caused by bisphenol A through inhibition of apoptosis and reduction of α-synuclein in rats
by: Majid Keshavarzi, et al.
Published: (2025-02-01)

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading
by: Yuanxi Li, et al.
Published: (2025-07-01)

Topological Features of ic- Open Sets
by: Beyda S. Abdullah, et al.
Published: (2023-01-01)

by: Kaoui, Badr
Published: (2025-06-01)

Validation of a Rapid, High-Throughput Isothermal Recombinase Polymerase Amplification Screening Assay for Phytophthora ramorum
by: Kerri A. Neugebauer, et al.
Published: (2025-06-01)

Preventing DNS misuse for Reflection/Amplification attacks with minimal computational overhead on the Internet
by: Rebeen Rebwar Hama Amin, et al.
Published: (2020-12-01)

Multivalent design of the monoclonal SynO2 antibody improves binding strength to soluble α-Synuclein aggregates
by: Inga Petersen, et al.
Published: (2023-12-01)

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression
by: María Berrocal, et al.
Published: (2025-08-01)

Development of Enzyme-Mediated Duplex Exponential Amplification Assay for Detection and Identification of <i>Meloidogyne enterolobii</i> in Field
by: Bingxue Sun, et al.
Published: (2025-06-01)

Discovery of <i>N</i>-(6-Methoxypyridin-3-yl)quinoline-2-amine Derivatives for Imaging Aggregated α-Synuclein in Parkinson’s Disease with Positron Emission Tomography
by: Haiyang Zhao, et al.
Published: (2025-07-01)

Modern technology of investment casting for the production of artistic castings
by: S. S. Tkachenko, et al.
Published: (2021-03-01)

Altered reactivity to threatening stimuli in Drosophila models of Parkinson’s disease, revealed by a trial-based assay
by: Márton Kajtor, et al.
Published: (2025-07-01)

Rapid detection of Pseudomonas aeruginosa by cross priming amplification
by: Yong XIANG, et al.
Published: (2020-10-01)

Lewy body dementias: One spectrum or two diseases?
by: Varsha Ratan Gaikwad, et al.
Published: (2025-07-01)

An Experimental Study of the Server-based Unfairness Solutions for the Cross-Protocol Scenario of Adaptive Streaming over HTTP/3 and HTTP/2
by: Chanh Minh Tran, et al.
Published: (2021-12-01)

Establishment and Application of Loop-Mediated Isothermal Amplification Assays for Pathogens of Rice Bakanae Disease
by: Xinchun Liu, et al.
Published: (2025-06-01)

Advanced solid materials for the extraction of drugs from biological fluids
by: P. García-Atienza, et al.
Published: (2025-08-01)

Loop-Mediated Isothermal Amplification (LAMP) Assay for Rapid Detection of Salmonella enterica in Low-Resource Settings
by: Umar Muhtar Nasir, et al.
Published: (2025-06-01)

Progress in the application of isothermal amplification technology in the diagnosis of infectious diseases
by: Qingshang Bi, et al.
Published: (2025-07-01)

Power Amplification and Selectivity in the Cochlear Amplifier
by: Piotr KIEŁCZYŃSKI
Published: (2013-03-01)

RADIATION HARDENED ANALOG IC FOR SENSOR
by: O. V. Dvornikov, et al.
Published: (2015-04-01)