A novel ultrasound-responsive cluster bomb system for efficient siRNA delivery in brain

RNA-based therapeutics using RNA interference have become a research hotspot for brain tumors and neurodegenerative diseases with the advancement of nanocarrier delivery technology. However, even with specific modifications, RNA-loaded nanoparticles face significant challenges in effectively crossin...

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Bibliographic Details
Main Authors: Tianyu Guo, Feihong Dong, Jingyi Yin, Xinnan Wang, Pengting Min, Jiabin Zhang, Heping Cheng, Jue Zhang
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ultrasonics Sonochemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S1350417725002251
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