A novel ultrasound-responsive cluster bomb system for efficient siRNA delivery in brain

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A novel ultrasound-responsive cluster bomb system for efficient siRNA delivery in brain

RNA-based therapeutics using RNA interference have become a research hotspot for brain tumors and neurodegenerative diseases with the advancement of nanocarrier delivery technology. However, even with specific modifications, RNA-loaded nanoparticles face significant challenges in effectively crossin...

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Bibliographic Details
Main Authors:	Tianyu Guo, Feihong Dong, Jingyi Yin, Xinnan Wang, Pengting Min, Jiabin Zhang, Heping Cheng, Jue Zhang
Format:	Article
Language:	English
Published:	Elsevier 2025-09-01
Series:	Ultrasonics Sonochemistry
Subjects:	Gene drug Nanoparticles Nanodroplets Blood-brain barrier Ultrasound
Online Access:	http://www.sciencedirect.com/science/article/pii/S1350417725002251
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