Cannabidiol Effects on Depressive-like Behavior and Neuroinflammation in Female Rats Exposed to High-Fat Diet and Unpredictable Chronic Mild Stress

Cannabidiol Effects on Depressive-like Behavior and Neuroinflammation in Female Rats Exposed to High-Fat Diet and Unpredictable Chronic Mild Stress

Depression and obesity are comorbid conditions linked through shared neuroinflammatory and immune mechanisms. This study examined the effects of chronic cannabidiol (CBD) treatment on behavior and neuroinflammatory gene expression in female rats exposed to a combined model of high-fat diet (HFD) and...

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Bibliographic Details
Main Authors: Tal Sabbag, Milly Kritman, Irit Akirav
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
depression
obesity
cannabidiol
high-fat diet
unpredictable chronic mild stress
neuroinflammation
Online Access:https://www.mdpi.com/2073-4409/14/12/938
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https://www.mdpi.com/2073-4409/14/12/938

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