Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

IntroductionStudies suggest that immune checkpoints play a role in accelerating the formation of atherosclerosis. We aimed to assess the expression of soluble and membrane-bound immune checkpoints in patients with peripheral artery disease (PAD).MethodsThe levels of 14 soluble immune checkpoints wer...

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Bibliographic Details
Main Authors: Rosanne D. Reitsema, Seta Kurt, Ignacio Rangel, Hans Hjelmqvist, Mats Dreifaldt, Allan Sirsjö, Ashok Kumar Kumawat
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
peripheral artery disease
intermittent claudication
immune checkpoints
T cells
antigen presenting cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1568431/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1568431/full

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