The biological agent rituximab ameliorates DNA damage and repair efficiency in the somatic cells of arthritic mice

The biological agent rituximab ameliorates DNA damage and repair efficiency in the somatic cells of arthritic mice

Background: Rheumatoid arthritis (RA) is an autoimmune disorder that deteriorates joints and can affect various physiological systems if not properly managed. The persistent joint inflammation and oxidative damage caused by RA can lead to genomic instability, a primary feature of most cancer cells....

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Bibliographic Details
Main Authors: Mohammed A. Al-Hamamah, Mohamed A. Mahmoud, Moureq R. Alotaibi, Ahmed Nadeem, Mushtaq A. Ansari, Sheikh F. Ahmad, Saleh A. Bakheet, Gamaleldin I. Harisa, Sabry M. Attia
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Electronic Journal of Biotechnology
Subjects:
Anti-CD20 monoclonal antibody
Arthritic mice
Autoimmune disease
DNA damage
DNA repair
Genomic instability
Online Access:http://www.sciencedirect.com/science/article/pii/S0717345825000168
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