Search Results - myocardial perfusion and function in translated hearts
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Macrophage-Secreted U2AF1 Orchestrates Coronary Artery Angiogenesis to Facilitate Myocardial Infarction Repair Through the Regulation of Yap1 Variable Splicing
Published 2025-07-01“…Plasma U2AF1 levels were measured in 70 MI patients, revealing significantly lower levels in individuals with poor coronary collateral vessel (CCV; Rentrop scores 0–1) than in those with good CCV (Rentrop scores 2–3). In both myocardial and hindlimb ischemia mouse models, overexpression of endothelial cell-specific adenoviral overexpression U2AF1 promoted angiogenesis in the heart and hindlimbs and improved cardiac function after MI. …”
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Synthetic antioxidant TS-13 reduces doxorubicin cardiotoxicity
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