Search Results - microarray analysis techniques

Navigating the microarray landscape: a comprehensive review of feature selection techniques and their applications by Fangling Wang, Azlan Mohd Zain, Yanjie Ren, Mahadi Bahari, Azurah A. Samah, Zuraini Binti Ali Shah, Norfadzlan Bin Yusup, Rozita Abdul Jalil, Azizah Mohamad, Nurulhuda Firdaus Mohd Azmi

“…This review systematically summarizes recent advances in microarray feature selection techniques and their applications in biomedical research. …”
Get full text

Application of chromosome microarray analysis and karyotyping in fetal cardiac abnormalities by Yun Guo, Xiaoqin Xin, Linju Zhou, Jungao Huang

“…ObjectiveChromosome microarray analysis (CMA) and karyotyping are two important genetic testing techniques used in prenatal diagnosis. …”
Get full text

APPLICATION OF SOLID-PHASE, ENZYME-LINKED IMMUNOASSAYS IN MICROARRAY FORMATE FOR QUANTITATIVE DETERMINATION OF CYTOKINES by M. A. Plotnikova, S. A. Klotchenko, V. V. Egorov, K. P. Nikulenkov, A. V. Vasin, O. I. Kisselev

Get full text

Differential expression analysis with inmoose, the integrated multi-omic open-source environment in Python by Maximilien Colange, Guillaume Appé, Léa Meunier, Solène Weill, Akpéli Nordor, Abdelkader Behdenna

“…Abstract Background Differential gene expression analysis is a prominent technique for the analysis of biomolecular data to identify genetic features associated with phenotypes. …”
Get full text

Identification of a novel microdeletion at 9q21.13 in a family with epilepsy, intellectual disability, and speech disorders and literature review by Liqing Jiang, Liqing Jiang, Liqing Jiang, Jiaqi Li, Aizhong Han, Aizhong Han, Aizhong Han, Fei Hou, Fei Hou, Fei Hou, Xiaotong Wei, Yanjun Tian, Yanjun Tian, Yanjun Tian

“…Whole exome sequencing (WES) and chromosome microarray analysis (CMA) techniques were used for genetic testing. …”
Get full text

HEREDITARY DISEASES AND SYNDROMES ACCOMPANIED BY FEBRILE CONVULSIONS: CLINICAL AND GENETIC CHARACTERISTICS AND DIAGNOSTIC PROCEDURES by E. L. Dadali, A. A. Sharkov, I. V. Sharkova, I. V. Kanivets, F. A. Konovalov, I. A. Akimova

“…It also determines the significance of using a chromosomal microarray analysis to diagnose both chromosomal and monogenic diseases accompanied by convulsions.…”
Get full text

Molecular mechanisms after optic nerve injury: Neurorepair strategies from a transcriptomic perspective by Xiaxue Chen, Muyang Wei, Guangyu Li

“…With advancements in high-throughput technologies, techniques such as microarray analysis, RNA sequencing, and single-cell RNA sequencing have been widely applied to characterize the transcriptomic profiles of retinal ganglion cell injury, revealing underlying molecular mechanisms. …”
Get full text

Application of family whole-exome sequencing for prenatal diagnosis—an analysis of 357 cases by Yijun Ge, Huizhen Yuan, Yao Yu, Junfang Xiao, Danping Liu, Yongbao Peng, Ying Liu, Shuhui Huang, Bicheng Yang, Yongyi Zou, Yanqiu Liu

“…ObjectiveTranslation of fertility risks through whole-exome sequencing of family lines to identify variants that explain patient’s clinical phenotypes.Methods1. Using techniques such as amniotic fluid, chorionic villus, or umbilical cord blood sampling, intact fetal cells were extracted for cell culture and subsequently analyzed using chromosomal karyotyping and chromosomal microarray techniques. 2. …”
Get full text

Clinical profile and cytogenetics of siblings with Jacobsen syndrome by Abinaya Gunalan, Priya Jose, Allen David, Peter Prasanth Kumar Kommu

“…Over time, a gradual move toward a “genotype-first” strategy and growing use of genome-wide testing techniques such as chromosomal microarray analysis and next-generation sequencing have been noted to facilitate arriving at the diagnosis. …”
Get full text

A new method for analyzing gene expression data by PAN Hai-yan, ZHU Jun, HAN Dan-fu

“…Microarray technique provides a systematic genome-wide approach to solve a wide range of problems such as gene functions, gene regulations, and the disease diagnoses and treatments. …”
Get full text

SMALL NONCODING RNA AS PERSPECTIVE BIOMARKERS: BIOGENESIS AND THERAPEUTIC STRATIGIES by V. V. Tiguntsev, S. A. Ivanova, V. Yu. Serebrov, M. B. Buhareva

“…The paper considers techniques to study noncoding RNA (cloning, bioinformatics analysis and hybridization methods: northern-blotting, RT-PCR, in situ hybridization, microarray analysis, reporter analysis). …”
Get full text

Role of Genetic and Epigenetic Factors and Mechanisms Involved in the Occurrence of Congenital Heart Diseases (CHD) by Fateme Tabrizi, Mehri Khatami, Mohammad Mehdi Heidari

“…Advanced research in molecular genetics, especially techniques such as whole-exome sequencing and chromosomal microarray analysis, which focus on protein-coding regions of the human genome, has identified hundreds of genes associated with the development of CHD. …”
Get full text

Advanced Molecular-Genetic Methods and Prospects for Their Application for the Indication and Identification of <i>Yersinia pestis</i> Strains by K. A. Nikiforov

“…The main groups of methods considered are as follows: based on the analysis of the lengths of restriction fragments (ribo- and IS-typing, pulse gel electrophoresis); based on the analysis of specific fragments (DFR typing, VNTR typing); based on sequencing (MLST, CRISPR analysis, SNP analysis); PCR methods (including IPCR, SPA); isothermal amplification methods (LAMP, HDA, RPA, SEA, PCA, SHERLOCK); DNA-microarray; methods using aptamer technology; bio- and nano-sensors; DNA origami; methods based on neural networks. …”
Get full text

Reconstructing Dynamic Gene Regulatory Networks Using f-Divergence from Time-Series scRNA-Seq Data by Yunge Wang, Lingling Zhang, Tong Si, Sarah Roberts, Yuqi Wang, Haijun Gong

“…Our approach integrates a first-order Granger causality model with various regularization techniques and partial correlation analysis to reconstruct gene regulatory networks from scRNA-seq data. …”
Get full text

Exposing Optimal Feature Sets for Enhancing Machine Learning Performance by Hiba Mohammed Al-Marwai, Ghaleb H. Al-Gaphari, Mohammed Mohammed Zayed

“…To evaluate the effectiveness of our approach, we conduct experiments on benchmark microarray datasets from the ADNI database. Comparative analysis is performed against six traditional single objective methods and five other existing multiobjective methods. …”
Get full text

The novel diagnostic markers for systemic lupus erythematosus and periodontal disease by Xuedi Cheng, Jinfeng Zhang, Jiali Hou, Xiaocui Han, Bin Han, Jun Zhou, Zhongjun Wang, Junzheng Wang

“…Protein-protein interaction (PPI) network analysis was conducted to explore relationships between hub genes. …”
Get full text

Role of laboratory biomarkers in monitoring and prediction of the effectiveness of treatment of rheumatic diseases using genetically engineered drugs by Elena Nikolayevna Aleksandrova, A A Novikov, E L Nasonov

“…In addition to the conventional uniplex immunodiagnostics techniques, multiplex analysis of marker, which is based on genetic, transcriptomic and proteomic technologies using DNA and protein microarrays, polymerase chain reaction, and flow cytometry, is becoming increasingly widespread. …”
Get full text