Hakutulokset - Lung function
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Periostin as a predictor of uncontrolled asthma and lung function decrease in patient of different age groups
Julkaistu 2021-06-01Hae kokotekstiIntroduction. Uncontrolled bronchial asthma (BA) increases risk of hospitalizations, future exacerbations and decreases quality of life; factors improving the probability to achieve BA control are under study.Methods and materials. The open prospective study included 104 patients of three groups: ch...
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An in vitro model of the epithelial airway reveals a key function for EHF in lung homeostasis and disease
Julkaistu 2025-06-01 Hae kokoteksti
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Assessment of ventilation heterogeneity in severe asthma using phase‐resolved functional lung magnetic resonance imaging
Julkaistu 2025-06-01Aiheet: Hae kokotekstiAbstract Ventilation heterogeneity is a hallmark of asthma. This study examines the feasibility of phase‐resolved functional lung magnetic resonance imaging (PREFUL MRI) in the evaluation of ventilation heterogeneity in severe asthma, its response to bronchodilator, and correlation with spirometry....
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Chest wall strapping in a porcine model: Dynamic dysanapsis dilates airways for optimized function of the “oversized” lung
Julkaistu 2025-08-01Hae kokotekstiChest-Wall-Strapping (CWS), a technique forcing the lung to operate at low volumes, is a model for an oversized lung allograft. Dynamic-dysanapsis describes airway dilation mediated by increased elastic recoil from CWS. We hypothesized that Dynamic-dysanapsis can be quantified via the Dysanapsis-Rat...
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Impact of Emphysema Subtypes and Volume on Lung Ventilation and Gas Exchange Functions as Evidenced by Computed Tomography
Julkaistu 2022-02-01“…Objective: to characterize the relationship between the subtype and volume of pulmonary emphysema on the indicators of lung ventilation and gas exchange functions. Material and methods. …”Objective: to characterize the relationship between the subtype and volume of pulmonary emphysema on the indicators of lung ventilation and gas exchange functions. Material and methods. The data of radiation and functional studies were analyzed in 50 patients. The inclusion criteria were chronic obs...
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Esophageal Diameter on High-Resolution Computed Tomography – a Potential Useful Marker for Interstitial Lung Disease Severity in Patients with Systemic Sclerosis
Julkaistu 2024-01-01Aiheet: Hae kokotekstiPatients with systemic sclerosis (SSc) are at an increased risk of developing interstitial lung disease (ILD) and esophageal dysfunction, with frequently present esophageal dilatation. Our study aimed to investigate the relationship between esophageal diameter (ED) analyzed on high-resolution com...
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Acute adrenaline myocardial necrosis prevention by artificial lung ventilation in experimental settings
Julkaistu 2007-02-01Aiheet: Hae kokotekstiIn experimental settings, hystotoxic catecholamine doses depress cardiomyocyte contractility, induce arrhythmia, and heart arrest. Edema and hemorrhages in lung tissue and myocardium, myocardial hemomicrocirculation disturbances, significantly disturbed CO2, O2 partial pressure, and blood pH, plus i...
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Effect of bronchodilator therapy on the function of external respiration and lung parenchyma in surgical treatment of patients with non-small cell lung cancer combined with chronic obstructive pulmonary disease
Julkaistu 2023-11-01“…All patients underwent tests of pulmonary function (spirometry, body plethysmography), measurement of lung parenchyma density and emphysematous lung areas (high-resolution computed tomography).Results. …”The purpose of the study was to compare the efficacy of regular prolonged inhalation therapy with tiotropium bromide delivered via the Respimat inhaler and short-acting bronchodilator (SAB) therapy with ipratropium bromide/fenoterol in the perioperative period in patients with non-small cell lung ca...
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Changes in the function of external breathing in patients who underwent lung decortication after post-pneumonic pleurisy
Julkaistu 2025-06-01“…This article explores changes in pulmonary function in patients who underwent lung decortication as a method of treating complications caused by post-pneumonic pleurisy. …”This article explores changes in pulmonary function in patients who underwent lung decortication as a method of treating complications caused by post-pneumonic pleurisy. It is emphasized that complications such as post-pneumonic pleurisy may lead to the formation of pulmonary fibrosis, which results...
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Dynamics of characteristics of respiratory function for the development of coronary heart disease in patients with chronic obstructive lung disease
Julkaistu 2019-03-01Hae kokotekstiChronic obstructive pulmonary disease (COPD), along with cardiovascular disease, belongs to the leading chronic non-infectious diseases of our time, which, occurring in comorbidity, lead to the development of severe mutually aggravating complications.Objective: to determine the methods of diagnosis...
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Lung function dynamics in smoking and non-smoking patients with stable effort angina, treated with beta-adrenoblockers
Julkaistu 2004-04-01Hae kokoteksti.
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Unveiling the Role of Cathepsins on Lung Function in Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Analysis
Julkaistu 2025-06-01Aiheet: Hae kokotekstiXuemin Zhang,1– 4 Xintong Li,1– 4 Shuang Song,1– 4 Changhong Miao,4 Long Yan,4 Xiaolong Xu,1– 3 Qingquan Liu1– 3 1Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, People’s Republic of China; 2Beijing Institute of Traditional Chinese Medicine, Beijing, 10...
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The association between high atherogenic index of plasma and impaired lung function: a population-based study
Julkaistu 2025-07-01Aiheet: Hae kokotekstiObjectiveAlthough AIP is a recognized cardiovascular risk marker, its association with pulmonary function and sex-specific differences remains unclear. This study investigated whether elevated AIP is independently associated with reduced lung function and examined potential sex-specific patterns.Met...
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External Respiratory Function Changes in Liver Cirrhosis with Different Types of Portal Blood Flow
Julkaistu 2012-03-01Aiheet: Hae kokotekstiPurpose: To establish the dependence of some leading indicators spirogram on the type of portal blood flow (PBF) in patients with liver cirrhosis (LC).Materials and Methods: Leading indicators of pulmonary ventilation and the most significant parameters were determined from the PC CPU 161 patients (...
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CYTOPROTECTIVE THERAPY POTENTIAL IN PATIENTS WITH CHRONIC COR PULMONALE
Julkaistu 2010-10-01Aiheet: Hae kokotekstiThe study investigated effectiveness and safety of a cytoprotector mexicor in patients with chronic cor pulmonale (CCP). All participants (n=56; age 38-80 years) were divided into four groups. Group I (n=16) received a standard pulmonary therapy, while Group II (n=20) also received mexicor (300 mg/d...
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Effect of home-based pulmonary rehabilitation on ventilation dynamics and small airway dysfunction in people with post-tuberculosis lung disease
Julkaistu 2025-08-01“…Before and after HBPRP, the following assessments were performed: QoL using the St George’s Respiratory Questionnaire (SGRQ), general fatigue using the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), handgrip strength (HGS), pulmonary function, and functional exercise capacity using the Glittre-ADL test (TGlittre) coupled with measurement of dynamic ventilation. …”Background: As the world moves toward eliminating tuberculosis (TB), there is a large population of TB survivors who still face a significant burden of TB complications. However, basic pulmonary rehabilitation program (PRP) packages for this population are currently lacking. This study aimed to eval...
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CYTOKINE PROFILE AND ADHESION MOLECULES IN THE PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG DISEASE COMBINED WITH BRONCHIAL ASTHMA
Julkaistu 2014-07-01Hae kokotekstiThe study involved 56 patients with chronic obstructive pulmonary disease (COPD), stage III-IV, 38 patients with severe bronchial asthma (BA), and 45 patients with a combination of COPD stage III-IV and bronchial asthma at exacerbation period. In all the patients, we have measured blood levels of pr...
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Lung functions and IgE component sensitizations: Five wheezing phenotypes in adolescents from the T-Child study in Tokyo
Julkaistu 2025-08-01Aiheet: Hae kokotekstiBackground: The endophenotypes of allergic disorders are known to vary across racial groups, underscoring the importance of studying allergic disease phenotypes in the population of Tokyo. Objective: We sought to elucidate the developmental trajectories of wheezing among adolescents and their associ...
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RELATION OF THE MARKERS OF MYOCARDIAL DYSFUNCTION AND SYSTEMIC INFLAMMATION WITH STRUCTURAL AND FUNCTIONAL PARAMETERS OF THE LUNGS IN MYOCARDIAL INFARCTION PATIENTS
Julkaistu 2018-04-01“…Assessment of lung function and blood collection were done at 1012 day of STEMI. …”Aim. To evaluate the structural and functional changes in the lungs of ST elevation myocardial infarction (STEMI) patients with absence or presence of chronic obstructive lung disease (COPD), and the relation with myocardial dysfunction and systemic inflammation.Material and methods. Totally, 189 ST...
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Digitoflavone Ameliorates Acute Lung Injury via Disturbing the Formation of Functional Stimulator of Interferon Genes Signalosome
Julkaistu 2025-04-01“…Next, we examined the effect of DG on STING downstream signaling events, such as STING oligomerization and functional STING signalosome formation. Using in vivo experiments, the 5,6-dimethylxanthenone-4-acetic acid (DMXAA)-induced agonist and lipopolysaccharide-induced acute lung injury models were used to assay the therapeutic effects of DG. …”Objective: The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon (IFN) genes (STING) signaling pathway has been implicated in the initiation and maintenance of a variety of inflammatory diseases. Thus, the search for modulators of the cGAS-STING signaling pathway is likely to contribute to the...
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