Αποτελέσματα αναζήτησης - "short tandem repeat"
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Microsatellite instability (MSI, EMAST) in the pathogenesis of follicular lymphoma
Έκδοση 2021-06-01Θέματα: Λήψη πλήρους κειμένουBackground. Genetic instability, an important phenomenon involved in oncogenic transformation and tumor progression, is associated with the insufficiency of the multicomponent DNA repair complex, in particular, the nucleotide mismatch repair (MMR) system. The MMR defect manifests itself as abnormali...
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Сhallenging Questions of Development and Application of DNA Banks for the Purposes of Criminology and Related Disciplines
Έκδοση 2019-05-01Θέματα: Λήψη πλήρους κειμένουReview article presents essential information on DNA databases, forensic genomics for human identification and suspect characteristics. Author reports the essential information on the topic of forensic DNA databases and data processing. DNA databases are important tools for the improvement of perfor...
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Using short tandem repeat profiling to validate cell lines in biobanks
Έκδοση 2022-12-01Θέματα: Λήψη πλήρους κειμένουAim. To approve the COrDIS kit (Gordiz, Russia) for the authenticity of cell lines from the Bioresource Collection of the N.N. Blokhin National Medical Research Center of Oncology by the short tandem repeat (STR) profiling.Material and methods. The chosen method proved to be a reliable and reproduci...
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Comparison of Fecal DNA Extraction Kits for the Giant Panda (Ailuropoda melanoleuca) by Short Tandem Repeat Genotype Analysis
Έκδοση 2025-04-01Θέματα: Λήψη πλήρους κειμένουABSTRACT Genetic analysis of short tandem repeat (STR) loci using noninvasive fecal samples is currently the most widely used method in genetic surveys of giant pandas (Ailuropoda melanoleuca). However, low‐quality fecal DNA obtained from fecal samples may affect the accuracy of short tandem repeat...
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Get ready for short tandem repeats analysis using long reads-the challenges and the state of the art
Έκδοση 2025-07-01Θέματα: “…short tandem repeats…”Short tandem repeats (STRs) are repetitive DNA sequences that contribute to genetic diversity and play a significant role in disease susceptibility. The human genome contains approximately 1.5 million STR loci, collectively covering around 3% of the total sequence. Certain repeat expansions can sign...
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Quantitative analysis of chimerism after allogeneic hematopoietic stem cell transplantation with molecular genetic methods
Έκδοση 2014-09-01Θέματα: Λήψη πλήρους κειμένουQuantitative monitoring of chimerism after allogeneic hematopoietic stem cell transplantation (HSCT) by molecular methods has becomea significant diagnostic tool in detection of engraftment / graft failure, predicting rejection and disease relapse. Despite the great utility of chimerism analysis the...
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Analysis of microsatellite aberrations and loss of heterozygosity in follicular lymphoma, diffuse large B-cell lymphoma, and high-grade B-cell lymphoma patients
Έκδοση 2022-04-01Θέματα: Λήψη πλήρους κειμένουBackground. The study of genetic predictors of non-Hodgkin’s lymphomas prognosis is one of the most relevant areas of oncohematology. It is extremely interesting to search for integral markers that reflect the most important stages of tumor pathogenesis. DNA repair system plays one of the key roles...
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