Search Results - "sepsis"

Background. Given that the imbalance in pro- and anti-inflammatory cytokines plays an important role in the pathogenesis of sepsis, estimation of its prognostic value in patients in the early stages from the disease onset or injury is of concern.Aim of study. To study changes in concentrations of bi...

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The aim of this review is to analyze the usefulness of the diagnostic sepsis marker – presepsin.Materials and methods. A search for relevant publications on presepsin was conducted using  the PubMed database of medical and biological publications and the eLIBRARY.com scientific electronic library. T...

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AbstractSepsis is a heterogeneous and life-threatening condition caused by a dysregulated immune response to infection. The most severe form of sepsis is septic shock, characterized by arterial hypotension, impaired tissue perfusion, and hypoxia. Despite new findings in antimicrobial and intensive c...

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The course of sepsis can be peracute in HIV patients, and its initial manifestations could be non-specific (a headache, inadequate behavior etc.) thus it can be difficult to be diagnosed. Sepsis is to be differentiated in intravenous drug users from narcotic intoxication and abstinence. The article...

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Relevance. The severe brain damage in most cases leads the patient to a long-term chronic critical condition (CCS). Regardless of the underlying  disease that led to CCS, patients will have a certain imbalance of neurohumoral regulation and characteristic cognitive, muscle-reflex disorders.  This co...

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Aim: to study characteristics of the central hemodynamics (CHD) in patients with severe abdominal sepsis with different outcomes of the disease.Materials and Methods. 18 patients with abdominal sepsis, aged 50.2±3, with the APACHE II and SOFA severity scoring of 13.7±0.8 and 8.4±0.5, respectively, w...

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Background: Neonatal sepsis is one of the leading causes of morbidity and mortality in neonates. The subtle clinical signs may sometimes go unnoticed. Blood culture is considered to be the gold standard, however it is time consuming. This may result in unnecessary and prolonged exposure to antibioti...

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LatarBelakang : Sepsis dan syok sepsis merupakan suatu sindroma kompleks dan multifaktorial, yang insidensi, morbiditas, dan mortalitasnya masih tinggi di dunia. Faktor - faktor yang mempengaruhi dan memperberat perjalanan penyakit sepsis diantaranya usia, jenis kelamin, fokus infeksi, skor APACHE I...

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The objective of this study was to determine the epidemiological, clinical, and laboratory characteristics of newborns with sepsis in northwestern Mexico, identify the microorganisms causing early- and late-onset sepsis, and assess antimicrobial resistance. Additionally, it sought to associate neona...

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Introduction. Sepsis is a serious life-threatening disease, accompanied by high mortality and long-term decline in the quality of life of surviving patients. Recent recommendations from the US Society of Critical Care Medicine presented the Phoenix Sepsis Score as the optimal system for assessing or...

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Patients with sepsis are an extremely heterogeneous group in terms of characteristics of autogenous response to infectious matter. The analysis is carried out for the employment feasibility of the teragnostics fundamentals in management of patients with sepsis. Consideration of the positive examples...

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IntroductionEarly identification of sepsis in the emergency department using machine learning remains a challenging problem, primarily due to the lack of a gold standard for sepsis diagnosis, the heterogeneity in clinical presentations, and the impact of confounding conditions.MethodsIn this work, w...

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Objective(s): Sepsis, a severe consequence of infection leading to organ failure, incites damage in frequently affected brain tissue through inflammation and oxidative stress. This study aimed to assess the effectiveness of amantadine, an N-methyl-D-aspartate (NMDA) receptor antagonist, in mitigatin...

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BackgroundUrogenic sepsis is a systemic inflammatory response syndrome triggered by infections of the genitourinary tract. It is characterized by complex etiology, atypical clinical symptoms, rapid disease progression, and difficulty in treatment, making it a focal point and challenge in clinical di...

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Purpose of the study: to investigate the epidemiology of sepsis in patients with different locations of the infection focus, who were admitted to the intensive care unit (ICU) of a multi-specialty hospital in 2014 and 2016.Material and methods. A retrospective analysis of examination and treatment o...

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<b>Background:</b> Sepsis remains a leading cause of mortality worldwide, and understanding endothelial damage is crucial for improving patient outcomes. Endothelial dysfunction in sepsis contributes to coagulopathy, increased capillary permeability, and vasoplegia, but the interplay bet...

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Sepsis is a potentially life-threatening state caused by an infection and an inadequate, dysregulated host immune response. Focusing on cardiac surgery, the prevalence of sepsis is low, after procedures situated between 0.39% and 2.5%. Nevertheless, the current life-expectancy of septic patients are...

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Abstract Background Sepsis-associated encephalopathy (SAE), a severe neurological complication of systemic infection, carries substantial morbidity and mortality risks. This study aims to examine the relationship between early acetaminophen use and survival rates in critically ill SAE patients. Meth...

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The article presents the features of the terminology of the main concepts on the problem, of sepsis from ancient times to the present. The contribution of Professor M. I. Lytkin to the development of the doctrine of surgical sepsis as the author of isolation and justification, of its independent for...

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Goal of the study: to study the frequency of myocardial dysfunction in sepsis patients and its impact on the outcome of the disease. Materials and Methods. 177 sepsis patients were enrolled into the retrospective cohort study. Myocardial dysfunction was diagnosed by transthoracic ultrasonic cardiogr...

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