Search Results - "real clinical practice"

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  1. 1
    PROBLEM OF TREATMENT WITH STATINS IN RUSSIA: WILL GENERICS HELP?

    PROBLEM OF TREATMENT WITH STATINS IN RUSSIA: WILL GENERICS HELP? by S. Y. Martsevich

    Published 2016-01-01

    The article underlines necessity of statins treatment for patients with high risk of cardio-vascular events. It is noted that in our country these drugs are used extremely seldom. The problem of generic-statins equivalence to original drugs is considered.

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  2. 2
    Strategies for control achievement in the real clinical practice settings. The data of ARROW-ACT study

    Strategies for control achievement in the real clinical practice settings. The data of ARROW-ACT study by Ye. S. Kulikov

    Published 2009-08-01

    At multicenter prospective observational study conducted in 19 centers in Russia under common protocol (n = 543) was demonstrated that in the context of real clinical practice the use of a step-up treatment regime and long-term dosing in a stable volume leads to control achievement in 73,3 and 69,4%...

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  3. 3
    The effectiveness of vortioxetine in patients with depression in real clinical practice

    The effectiveness of vortioxetine in patients with depression in real clinical practice by N. N. Petrova

    Published 2022-10-01

    The opinion article is devoted to the analysis of a large-scale 24-week multinational observational prospective cohort study «The effectiveness of vortioxetine in depression in real clinical practice» (BELIEVE). The study demonstrated the achievement of functional recovery of patients with depressiv...

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  4. 4
    Challenges of Statin Therapy in Clinical Practice (According to Outpatient Register «PROFILE» Data)

    Challenges of Statin Therapy in Clinical Practice (According to Outpatient Register «PROFILE» Data) by S. Yu. Martsevich, Yu. V. Lukina, N. P. Kutishenko, A. V. Zagrebelnyy, S. N. Tolpygina, V. P. Voronina, N. A. Dmitrieva, O. V. Lerman, E. S. Nekoshnova, I. V. Budaeva, S. V. Blagodatskikh, B. B. Aslanova

    Published 2022-03-01

    Aim. To identify the main problems of statin therapy in patients with high and very high cardiovascular (CV) risk in real clinical practice.Material and methods. The general information of the study was based on data from 2,457 patients who were included in the register before November 30, 2020: 1,2...

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  5. 5
    The impact of T2T therapy on the treatment of the patients with the early rheumatoid arthritis (data from OREL registry)

    The impact of T2T therapy on the treatment of the patients with the early rheumatoid arthritis (data from OREL registry) by V. V. Rybakova, A. S. Avdeeva, D. A. Dibrov, E. L. Nasonov

    Published 2021-07-01

    Aim – to analyze long-term results of intensive treatment initiated at rheumatoid arthritis (RA) onset in real clinical practice.Material and methods. 93 RA patients were included. Subcutaneous MTX was initiated at 10–15 mg per week with further dose escalation up to 20–30 mg per week. If MTX monoth...

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  6. 6
    One shot of hyaluronic acid in advanced knee osteoarthritis: postmarketing clinical follow-up for real-world evidence in a pain unit

    One shot of hyaluronic acid in advanced knee osteoarthritis: postmarketing clinical follow-up for real-world evidence in a pain unit by Pilar Acín, Amparo Santamaría, Elena Gómez-Rubio, Pilar Coronel Granado

    Published 2025-07-01

    Abstract Background this study aims to assess the real-world efficacy and safety of one shot of intraarticular (IA) hyaluronic acid (HA) in patients with advanced knee osteoarthritis (OA), in accordance with the requirement of the new EU Regulation on medical devices to monitor the safety and effica...

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  7. 7
    Guidelines "Medical registries. Role in evidence-based medicine. Recommendations for creation": a brief review

    Guidelines "Medical registries. Role in evidence-based medicine. Recommendations for creation": a brief review by S. Yu. Martsevich, Yu. V. Lukina, N. P. Kutishenko, S. N. Tolpygina, M. M. Lukyanov, O. M. Drapkina

    Published 2023-07-01

    The article provides a brief review of the guidelines on medical registries. The methodological recommendations are based on the accumulated clinical and scientific experience, data from domestic and foreign literature, expert consensus on the management of medical registers. The main types and goal...

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  8. 8
    Evaluation of rituximab therapy in real clinical practice (according to the OREL registry of patients with rheumatoid arthritis

    Evaluation of rituximab therapy in real clinical practice (according to the OREL registry of patients with rheumatoid arthritis by A. S. Avdeeva, A. M. Satybaldyev, N. V. Demidova, N. Yu. Nikishina, E. V. Gerasimova, N. V. Muravyeva, G. I. Gridneva, O. A. Rumyantseva, K. A. Kasumova, A. V. Alekseeva, N. V. Chichasova, D. A. Kusevich, V. V. Rybakova, E. A. Koshkarova, A. M. Lila, E. L. Nasonov

    Published 2019-07-01

    Objective: to analyze therapy with rituximab (RTM) in real clinical practice according to the data available in OREL registry of patients with active rheumatoid arthritis (RA).Subjects and methods. The analysis included 349 patients. All the patients received RTM: 340 – the original drug (MabThera®)...

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  9. 9
    Detection and Treatment of Hyperuricemia in Clinical Practice (According to the PROFILE Outpatient Registry)

    Detection and Treatment of Hyperuricemia in Clinical Practice (According to the PROFILE Outpatient Registry) by N. P. Kutishenko, S. Yu. Martsevich, A. V. Zagrebelnyy, Yu. V. Lukina, V. P. Voronina, N. A. Dmitrieva, O. V. Lerman, S. N. Tolpygina, S. V. Blagodatskikh, I. V. Budaeva, E. S. Nekoshnova, O. M. Drapkina

    Published 2022-09-01

    Aim. To study the frequency of detection of hyperuricemia (HU) in patients with high and very high cardiovascular risk and the frequency of prescribing drugs that lower serum uric acid (sUA) levels in real clinical practice.Material and methods: The general information of the study was based on the...

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  10. 10
    Adherence of the doctors to the up-to-date clinical recommendations in case follow-up of the patients affected by acute coronary syndrome

    Adherence of the doctors to the up-to-date clinical recommendations in case follow-up of the patients affected by acute coronary syndrome by O. Yu. Korennova, S. P. Podolnaya, E. P. Prikhodko, L. V. Shukil, I. V. Druk, E. A. Ryapolova

    Published 2021-06-01

    In the course of the case follow-up, clinical-expert analysis of validity of diagnosing «stenocardia» and «chronic heart insufficiency with retained and medium ejection fraction» was presented, as well as the strategies of management of the patients affected by acute coronary syndrome and x-ray-endo...

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  11. 11
    ANALYSIS OF THE RESULTS OF TOFACITINIB THERAPY IN REAL CLINICAL PRACTICE ACCORDING TO THE ALL-RUSSIAN ARTHRITIS REGISTRY (OREL)

    ANALYSIS OF THE RESULTS OF TOFACITINIB THERAPY IN REAL CLINICAL PRACTICE ACCORDING TO THE ALL-RUSSIAN ARTHRITIS REGISTRY (OREL) by A. S. Avdeeva, A. S. Misiyuk, A. M. Satybaldyev, G. V. Lukina, V. N. Sorotskaya, E. V. Zhilyaev, A. R. Babaeva, A. A. Baranov, V. I. Mazurov, I. N. Shendrygin, T. S. Salnikova, L. A. Knyazeva, D. G. Krechikova, R. R. Samigullina, I. Z. Gaidukova, D. I. Abdulganieva, I. N. Kushnir, O. N. Anoshenkova, N. A. Lapkina, E. A. Koshkarova, A. M. Lila, E. L. Nasonov

    Published 2020-06-01

    Objective: to analyze the results of tofacitinib (TOFA) therapy in real clinical practice according to the All-Russian Arthritis Registry (OREL). Subjects and methods. The OREL Registry included 347 patients (286 (82%) women and 61 (18%) men) with rheumatoid arthritis (RA) who initiated TOFA therapy...

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  12. 12
    The current standards for laboratory diagnosis of rheumatic diseases and their use in real clinical practice

    The current standards for laboratory diagnosis of rheumatic diseases and their use in real clinical practice by Elena Nikolaevna Aleksandrova, A A Novikov, E L Nasonov

    Published 2013-11-01

    The use of the current standards for laboratory diagnosis of rheumatic diseases (RD) in clinical practice was analyzed on the basis of the data obtained at the Laboratory for the Immunology and Molecular Biology of Rheumatic Diseases, V.A. Nasonova Research Institute of Rheumatology, Russian Academy...

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  13. 13
    EVALUATION BY PRACTICING DOCTORS OF THE MODERN PHARMACOTHERAPY POSSIBILITIES IN PATIENTS WITH ISCHEMIC HEART DISEASE. RESULTS OF DOCTOR INTERVIEW IN MOSCOW AND VORONEZH

    EVALUATION BY PRACTICING DOCTORS OF THE MODERN PHARMACOTHERAPY POSSIBILITIES IN PATIENTS WITH ISCHEMIC HEART DISEASE. RESULTS OF DOCTOR INTERVIEW IN MOSCOW AND VORONEZH by S. Yu. Martsevich, L. Yu. Drozdova, Yu. V. Lukina, N. V. Sinyagina, T. G. Kheliya

    Published 2016-01-01

    Aim. To evaluate opinion of doctors about modern pharmacotherapy possibilities in patients with ischemic heart disease (IHD) and about basic problems of pharmacotherapy implementation.Material and methods. Interviews of doctors from various health care institutions in Moscow and Voronezh were perfor...

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  14. 14
    Evaluation of Drug Therapy and Adherence to It in Patients after Acute Coronary Syndrome in Real Clinical Practice (Results of One Year Observation)

    Evaluation of Drug Therapy and Adherence to It in Patients after Acute Coronary Syndrome in Real Clinical Practice (Results of One Year Observation) by L. A. Khaisheva, S. E. Glova, V. A. Suroedov, A. S. Samakaev, S. V. Shlyk

    Published 2019-01-01

    Aim. To study the prescribed drug therapy, as well as adherence to it in patients with acute coronary syndrome (ACS) in real clinical practice within a year after the index event. Material and methods. The study included 327 patients who were in hospital treatment with ACS: 199 patients (60.9%) with...

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  15. 15
    Features and main problems of treating patients with high and very high cardiovascular risk with statins in real clinical practice (according to the data of the “PRIORITET” research)

    Features and main problems of treating patients with high and very high cardiovascular risk with statins in real clinical practice (according to the data of the “PRIORITET” researc... by S. Yu. Martsevich, Yu. V. Lukina, N. P. Kutishenko, N. A. Dmitrieva, T. A. Gomova, S. I. Drozdetsky, E. A. Kudryashov, O. V. Lerman, N. F. Puchinyan, V. V. Skibitsky

    Published 2018-12-01

    Aim. To determine the features and main problems of statin therapy, as well as assess the possibility of achieving the target level of lipid pattern in patients with high and very high cardiovascular risk (CVR) in real clinical practice.Material and methods. The design of the “PRIORITET” observation...

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  16. 16
    Lenvatinib Therapy in Patients with Unresectable Hepatocellular Carcinoma in Real Clinical Practice

    Lenvatinib Therapy in Patients with Unresectable Hepatocellular Carcinoma in Real Clinical Practice by V. V. Petkau, A. V. Sultanbaev, K. V. Menshikov, A. S. Antipin, M. V. Volkonsky, V. M. Filippova, Yu. V. Vasilyeva, A. A. Tarkhanov, M. R. Mukhitova, M. Zh. Murzalina, A. R. Safarova

    Published 2022-12-01

    Aim. To determine lenvatinib treatment outcomes in patients with advanced unresectable hepatocellular carcinoma (uHCC) in real clinical practice.Patients and methods. A multicenter retrospective observational study included 58 patients with a confirmed uHCC diagnosis receiving lenvatinib. At baselin...

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  17. 17
    The Effects of Telmisartan and Its Combinations on Office Blood Pressure: Results of Prospective Observational Study TAINA

    The Effects of Telmisartan and Its Combinations on Office Blood Pressure: Results of Prospective Observational Study TAINA by O. D. Ostroumova, A. I. Kochetkov, F. T. Ageev, G. S. Anikin, E. Kh. Akhmetzyanova, E. I. Bezuglova, A. B. Bekoeva, N. Yu. Borovkova, N. G. Vinogradova, E. V. Gorbunova, A. A. Goryacheva, E. S. Zhugrova, O. A. Kislyak, S. M. Klyashev, V. P. Kuzmin, A. A. Lipchenko, G. V. Matyushin, E. A. Mikhailova, V. A. Nevzorova, A. G. Obrezan, T. A. Petrichko, M. M. Petrova, A. N. Reider, A. N. Repin, V. I. Sadovoy, N. P. Sanina, A. E. Skripchenko, R. I. Stryuk, I. V. Faiyance, L. A. Khaisheva, N. R. Khasanov, R. A. Khokhlov, E. E. Tsareva, A. L. Cherkashina, I. I. Shaposhnik, I. A. Shelestova, R. N. Shepel, E. V. Shikh, D. A. Yakhontov

    Published 2020-05-01

    Aim. To evaluate the effectiveness and safety of telmisartan, used in monotherapy or in combination with hydrochlorothiazide or amlodipine, in real clinical practice in patients with diagnosed arterial hypertension who have not reached the target levels of blood pressure (BP).Material and methods. T...

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  18. 18
    How Does the Presence of Diabetes Affect the Course of Acute Coronary Syndrome in Elderly Patients in Actual Clinical Practice?

    How Does the Presence of Diabetes Affect the Course of Acute Coronary Syndrome in Elderly Patients in Actual Clinical Practice? by M. R. Atabegashvili, E. V. Konstantinova, M. D. Muksinova, A. E. Udovichenko, A. P. Nesterov, M. O. Zheltoukhova, L. S. kyzy Muradova, M. Y. Gilarov

    Published 2019-03-01

    The number of elderly patients with diabetes mellitus (DM) is constantly growing in general population. Accordantly, we have the growth of such patients in the group of acute coronary syndrome (ACS).Aim. To compare clinical characteristics of the elderly patient (>75 years old) with and witho...

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  19. 19
    MANAGEMENT OF PATIENT WITH ARTERIAL FIBRILLATION: WHAT`S NEW?

    MANAGEMENT OF PATIENT WITH ARTERIAL FIBRILLATION: WHAT`S NEW? by D. A. Napalkov, A. A. Sokolova

    Published 2016-12-01

    The literary review consists of two parts. The first takes into consideration the renewed European guidelines of 2016 for atrial fibrillation patients management. The accent is made on the renewed approaches for anticoagulation treatment regardless the gender, on new points in the risks of haemorrha...

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  20. 20
    TREATMENT IN PATIENTS WITH ANKYLOSING SPONDYLITIS IN THE REAL CLINICAL PRACTICE OF A RHEUMATOLOGIST IN RUSSIA

    TREATMENT IN PATIENTS WITH ANKYLOSING SPONDYLITIS IN THE REAL CLINICAL PRACTICE OF A RHEUMATOLOGIST IN RUSSIA by Sh F Erdes, Evgeny Vladimirovich Volnuhin, E A Galushko

    Published 2013-02-01

    Objective: to analyze the treatment of ankylosing spondylitis (AS) in the real practice of a rheumatologist in Russia. Subjects and methods. The cross-sectional study included 330 AS patients who had been actively seeking medical advice from rheumatologists during 4 months in 24 cities and towns of...

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