Search Results - "pyrazole"

In this paper, some chalcone derivatives (C1, C2) were synthesized based on the reaction of equal amount of substituted acetophenone and substituted banzaldehyde in basic medium. Oxazine and thiazine derivatives were prepared from the reaction of chalcones (C1-C2) with urea and thiourea respectively...

Full description

A novel magnetic nanocatalyst based on nickel ferrite coated with chitosan and ethylenediamine-functionalized β-cyclodextrin and decorated with cobalt nanoparticles (NiFe2O4@Cs-CDEDA@Co) was developed for the efficient green synthesis of heterocycles. This bifunctional catalyst provided Lewis acidic...

Full description

In this study, chalcones were synthesis by condensing 2-acetylpyridine with aromatic aldehyde derivatives in dilute ethanolic potassium hydroxide solution at room temperature according to Claisen-Schmidt condensation. After that, new heterocyclic derivatives such as Oxazine, Thiazine and Pyrazol wer...

Full description

In this work pyrazolin derivatives were prepared from the diazonium chloride salt of 4-aminobenzoic acid. Azo compounds were prepared from the reaction of an ethanolic solution of sodium acetate and calculated amount of active methylene compound namely, acetyl acetone to obtain the corresponding hy...

Full description

Synthesis of 1-(β-naphthyl)-3-ferrocenyl pyrazole-4-carbaldehyde was carried out from acetylferrocene and naphthalen-2-ylhydrazine followed by intramolecular cyclization under Vilsmeier-Haack conditions. The reaction of reductive amination of aldehydes obtained with primary and secondary amines incl...

Full description

Ionic liquids (ILs), also known as designer solvents, have emerged as highly significant in various areas of chemistry due to their unique properties, including low volatility, high thermal stability, and excellent solubility for a wide range of substances. These characteristics make ILs exceptional...

Full description

In this work 2-hydrazino pyrimidine (1) was prepared from 2-mercapto pyrimidine with hydrazine hydrate. Treatment of (1) with active methylene compounds gave 2-(3,5-dimethyl -1 H – Pyrazole-1-yl) pyrimidine , whereas the reaction of (1) with carboxylic anhydride namely maleic anhydride or 1,2,3,6...

Full description

In the context of palladium-catalyzed C–H bond arylation, it has been well-established that pyrazoles, with both C4 and C5 available positions, typically result in the formation of mixtures of C4-, C5-arylated, and also C4, C5-diarylated products. In this study, the reactivity of ethyl 1-methylpyraz...

Full description

High hydrostatic pressure (HHP) was found to be an efficient activation method in several catalyst- and solvent-free reactions and has found application for the syntheses of heterocycles and the preparation of active pharmaceutical ingredients (APIs) via acylation and acid- and solvent-free esterifi...

Full description

Objectives. The paper is devoted to the crystal structure characterization of 5-methyl-2-phenyl4H-pyrazol-3-one (compound I) and 2-(4-chlorophenyl)-5-methyl-4H-pyrazol-3-one (compound II).Methods. Single-crystal X-ray diffraction studies and theoretical calculations: Density functional theory and qu...

Full description

We investigated one-pot, three-component, and stepwise reactions of malononitrile and salicylic aldehydes (salicylic, 5-bromsalicylic) with N,N-nucleophiles, such as hydrazine hydrate, nitrobenzhydrazides, and o-phenylenediamine, under various conditions. This work reports on the synthesis of novel...

Full description

Preparation and Identification of some new Pyrazolopyrin derivatives and their Polymerizations study