Search Results - "personalized treatment"
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APPROACHES TO PERSONALIZED THERAPY
Published 2018-07-01Subjects: “…personalized treatment…”Approaches to personalized therapy based on practical work of physicians are discussed. Personalized treatment considers patient’s interests and position, mechanisms of symptoms, somatic and mental comorbidities, chrono medicine, environment, genetics, and prognosis. Personalized treatment may be mo...
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COMPLEX TREATMENT PRINCIPLES OF THE PATIENTS WITH THE ABNORMAL UTERINE BLEEDINGS IN THE PUBERTAL PERIOD
Published 2018-02-01Subjects: Get full textAim. To increase the effectiveness of the classical approach to the therapy of abnormal uterine bleeding by the phased use of personalized treatment regimens in conjunction with the methods of the physiotherapeutic methods.Materials and methods. The case maps of the girls of the pubertal period prev...
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P5 Model Approach in Alcohol Use Disorders: A Narrative Review of Deaddiction through Ayurveda Perspective
Published 2025-04-01Subjects: Get full textBackground: Ayurveda has long recognized the harmful effects of excessive alcohol consumption, known as Madatyaya. P5 model provides a holistic approach to alcohol abuse treatment. Ayurvedic management of alcohol use disorders (AUD) involves detoxification (Shodhana), modifications in diet and lifes...
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Current insights and trends in atopic dermatitis and microbiota interactions: a systematic review and bibliometric analysis
Published 2025-06-01Subjects: Get full textBackgroundAtopic dermatitis (AD) is a prevalent chronic inflammatory skin condition influenced by immune dysfunction, genetics, and environmental factors, with emerging evidence highlighting the critical role of skin and gut microbiota in its pathogenesis. This article uniquely integrates a systemat...
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What neural networks and how a urologist can utilize in his routine tasks: practical tips
Published 2025-03-01Subjects: Get full textArtificial intelligence (AI) is becoming an integral part of modern medicine, including urology. This article examines key approaches to implementing AI in diagnostics, treatment, and patient management. The focus is on the potential of neural networks, such as convolutional and recurrent networks,...
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Breast cancer. From molecular biology to personified therapy
Published 2016-03-01Subjects: Get full textAdvances in molecular biology had changed approaches to systemic treatment of breast cancer. Clinical decisions on the choice of optimal treatment regimens are performing on the basis of immunohistochemical and molecular genetic classifications. Their increasing uses have contributed changes of para...
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Update on thyroid nodules: Characteristics and clinical management
Published 2025-12-01Subjects: Get full textThyroid nodules (TNs) represent a highly widespread condition, usually destined to a positive outcome. Nevertheless, making a correct diagnosis is crucially important to ensure an appropriate and tailored strategy of follow up or treatment. Several different techniques allow to gradually characteriz...
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Personalized Treatment Response in Progressive MS: Can the Patient's Profile Influence the Outcome?
Published 2025-06-01Subjects: Get full textAbstract Background Evidence from clinical trials providing average effects in populations is often used to forecast individualized patient outcomes similar to the trial patients. Multiple sclerosis (MS), known for notable heterogeneity in outcomes, makes the evaluation of potential heterogeneity of...
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An Artificial Intelligence Pipeline for Hepatocellular Carcinoma: From Data to Treatment Recommendations
Published 2025-07-01Subjects: Get full textXuebing Zhang,1,2 Liuxin Yang,1 Chengxiang Liu,1,2 Xingxing Yuan,1,2 Yali Zhang1,2 1Department of Graduate Studies, Heilongjiang University of Chinese Medicine, Harbin, 150006, People’s Republic of China; 2Department of Gastroenterology, Heilongjiang Academy of Traditional Chinese Medicine, Harbin,...
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Analysis of gene polymorphisms in patients with pulmonary infections based on next-generation sequencing technology and their prognostic predictive value
Published 2025-07-01Subjects: Get full textPulmonary infections are a leading cause of morbidity and mortality worldwide, particularly among vulnerable populations such as children and the older adult. Gene polymorphisms play a critical role in disease susceptibility, progression, and prognosis, yet their specific contributions to pulmonary...
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Efficacy of Dupilumab in a Young Woman with Refractory Cutaneous Lichen Planus: A Case-Based Review
Published 2025-07-01Subjects: Get full text<i>Background:</i> Cutaneous lichen planus (CLP) is a chronic inflammatory T cell-mediated disease driven by a mixed Th1 and Th2 lymphocyte population, for which many of the currently available treatments have poor efficacy. <i>Aim:</i> The aim of this study was to indicate t...
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Artificial intelligence in human immunodeficiency virus mutation prediction and drug design: Advancing personalized treatment and prevention
Published 2025-12-01Subjects: Get full textDespite significant advancements in highly active antiretroviral therapy (HAART), Human Immunodeficiency Virus (HIV) remains a global health challenge due to its high mutation rate, drug resistance, and the complexity of treatment optimization. Artificial intelligence (AI) has emerged as a transform...
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Tianjin Medical University General Hospital
Published 2025-01-01Subjects: Get full textWith over 70 years of development, the Department of Obstetrics and Gynecology at Tianjin Medical University General Hospital has evolved into a comprehensive center for clinical care, research, and education, showcasing significant influence and technical strength in the field of obstetrics and gyn...
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A practical guide for nephrologist peer reviewers: evaluating artificial intelligence and machine learning research in nephrology
Published 2025-12-01Subjects: Get full textArtificial intelligence (AI) and machine learning (ML) are transforming nephrology by enhancing diagnosis, risk prediction, and treatment optimization for conditions such as acute kidney injury (AKI) and chronic kidney disease (CKD). AI-driven models utilize diverse datasets—including electronic hea...
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Integrative analysis of lactylation related genes in prostate cancer: unveiling heterogeneity through single-cell RNA-seq, bulk RNA-seq and machine learning
Published 2025-08-01Subjects: Get full textIntroductionLactylation, a post-translational modification characterized by the attachment of lactate to protein lysine residues on proteins, plays a pivotal role in cancer progression and immune evasion. However, its implications in immunity regulation and prostate cancer prognosis remains poorly u...
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mRNA-Based Biomarker Identification for Targeted Therapy Development in Pancreatic Cancer
Published 2025-03-01Subjects: Get full textPancreatic cancer is one of the highly malignant cancers that have poor prognosis and limited treatment options. The development of targeted therapies is important for improving patient outcomes. In this study, we analyzed the datasets from the GEO database to identify potential mRNA biomarkers for...
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Immunotherapy in Glioblastoma: An Overview of Current Status
Published 2025-07-01Subjects: Get full textZouina Sarfraz,1 Arun Maharaj,1 Vyshak Alva Venur,2 Justin D Lathia,3 Yazmin Odia,1 Manmeet S Ahluwalia1,4 1Miami Cancer Institute, Baptist Health South Florida, Miami, FL, USA; 2Seattle Cancer Care Alliance, Fred Hutchinson Cancer Center, University of Washington, Seattle, WA, USA; 3Cleveland Clini...
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Personalized Approach as a Basis for the Future Diagnosis of Tuberculosis (Literature Review)
Published 2019-07-01Subjects: Get full textThe global spread of tuberculosis remains one of actual problems of public health despite of introduction of public health safety programs. Early, rapid and accurate identification of M. tuberculosis and determination of drug susceptibility are essential for treatment and management of this disease....
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Integrating artificial intelligence in healthcare: applications, challenges, and future directions
Published 2025-12-01Subjects: Get full textArtificial intelligence (AI) has demonstrated remarkable potential in transforming medical diagnostics across various healthcare domains. This paper explores AI applications in cancer detection, dental medicine, brain tumor database management, and personalized treatment planning. AI technologies su...
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Detection of Cisplatin Resistance in Bladder Cancer Using Machine Learning
Published 2025-01-01Subjects: Get full textBladder Cancer (BC) is the ninth most common cancer worldwide, with cisplatin-based chemotherapy being a standard treatment. However, the emergence of cisplatin resistance poses significant challenges, contributing to high recurrence rates. This study investigates the mechanisms of cisplatin resista...
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