Search Results - "myocardial remodelling"

This study investigated the effects of hemodialysis, age, and gender on the development of various myocardial remodelling types. In total, 399 patients were examined: 184 on planned hemodialysis, 117 with pre-dialysis chronic kidney failure (CKF), and 98 with renal disease, but no CKF. All participa...

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Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporte...

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Ageing is an inevitable process which affects quality of life and reduces life expectancy. Age-related cardiac changes reduce compensatory reserves of the heart and accelerate the disease development. Such changes in cardiac structure and function, observed in the absence of cardiovascular disease (...

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The relation between renal diseases and cardiovascular morbidity is known since Richard Bright times, who was the first researcher on morphology of the left ventricle hypertrophy (LVH) in renal diseases. Since these times, an abundant research was done on LVH as one of the leading risk factors for h...

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In recent years, the mechanical support of blood circulation has proved to be a vital therapy for a terminal heart failure, and is considered as a "bridge" to transplantation or is used on a permanent basis in a patient who can not be included in the waiting list for a donor organ. Recent...

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Aim. To assess the specifics of myocardium remodeling in sportsmen-weightlifters according to presence of arterial hypertension (AH).Material and methods. Totally 80 sportsmen-weightlifters were included at the age of 21,0 (18,5-25,0) years. Group of AH consisted of 42 (52,5%) men, and the group wit...

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Aim. To study the effect of combined antihypertensive therapy on the basic parameters of the left ventricle (LV) myocardium structure and function in women with arterial hypertension (HT), metabolic syndrome (MS) and hypothyroidism. Material and methods. Women (n=196) with HT grade 2–3 and MS were i...

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Here the role of cardiomyocyte apoptosis in mechanisms of ischemic myocardial remodeling was investigated. The samples of left ventricle were obtained on 50 patients with the diagnosed atherosclerotic disease of coronary arteries and heart failure. Obtained data allow to approve about the maximal im...

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Aim. To study the age-related changes in structure of myocardium of the left ventricle and their relation with telomere length. With the age even in absence of cardiovascular diseases (CVD) and risk factors (CRF) there is a changing of the left ventricle (LV) myocardium structure. Probable mechanism...

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Increased LV myocardial mass (LVM) and alteration of its geometric model further cardiovascular risk and deteriorate prognosis in chronic renal failure (CRF).The aim of the study was to observe the fine mechanism of early myocardial remodeling on various stages of CRF. The study included 106 patient...

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Aim. To study the influence of nitric oxide (NO) on the types of remodeling of the left ventricle myocardium (LV) and hemodynamics parameters in patients with arterial hypertension (AH), inhabitants of the higher altitudes areas.Material and methods. In high altitudes of Elbrus areas we studied 170...

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Objective: to study the association between echocardiographic (EchoCG) parameters in type 2 diabetes mellitus (DM) patients and myocardial contractility and coronary angiographic status as evidenced by ventriculography and coronarography.Material and methods. One hundred and thirty-eight patients wi...

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Aim. To study the relationships between clinical and functional features of chronic obstructive pulmonary disease (COPD) and status of cardiovascular system with focus on identifying factors associated with the atrial fibrillation (AF) in patients with COPD.Material and methods. Patients (n=94) with...

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Aim. To study the relationships between clinical and functional features of chronic obstructive pulmonary disease (COPD) and status of cardiovascular system with focus on identifying factors associated with the atrial fibrillation (AF) in patients with COPD.Material and methods. Patients (n=94) with...

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Aim. To study structural changes in the myocardium of Wistar rats after a single administration of epinephrine.Material and methods. Structural changes in male Wistar rat’s left (LV) and right (RV) ventricle myocardium after a single injection of epinephrine were studied.Results. The density of extr...

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Aim. To study the myocardial remodeling features in patients with stable angina depending on disease severity and experienced myocardial infarction (MI).Material and methods. 148 male patients with stable angina were examined and randomized into 3 groups (G1-G3). 52 patients of G1 had angina of I-II...

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Background. The P-wave signal-averaged electrocardiogram (SAECG) abnormalities is noninvasive marker of atrial conduction delay and predictor of paroxysmal atrial fibrillation (AF). Aldosterone antagonists used as upstream AF therapy may be effective in prevention of AF episodes, but their impact on...

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Aim. To study the effect of ACE inhibitors (ACEI) in heart recipients on the prognosis and myocardial remodeling.Materials and methods. Three hundred and eighty-six patients who received orthotopic heart transplantation (HT) were consequently enrolled to the study from February 2009 to November 2016...

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Aim. To study the relationship between epicardial/visceral obesity and cardiac remodeling characteristics in patients with acquired mitral valve (MV) disease and indications for surgical treatment of the defect.Material and methods. The study included 49 patients hospitalized for surgery of non-infe...

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Introduction. Arterial hypertension is the most prevalent cardiovascular disease that leads to target organ damage, including the myocardium. Myocardial remodeling and fibrosis cause electrical and structural changes. Prolonged arterial hypertension with structural changes can lead to rhythm disturb...

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