Search Results - "itraconazole"

Introduction: Recently, there has been a change in the spectrum of dermatophytosis, shifting from Trichophyton rubrum, which was previously the most common species, to the more drug-resistant and chronic Trichophyton mentagrophytes. Although there have been several recent studies on dermatophytosis,...

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Phaeohyphomycosis is the term used to describe infections due to dematiaceous fungi which can cause cutaneous, pulmonary, and sinus infection, especially in immunocompromised patients. A 32-year-old deceased donor renal transplant recipient presented 8 months posttransplant with subcutaneous nodule...

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BackgroundAutophagy induced by itraconazole and ritonavir was found involved in the pathogenesis of C. albicans. This study was designed to explore the possible molecular mechanism of itraconazole and ritonavir in the treatment of Candida albicans infection through autophagy pathway.MethodsThe overl...

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Trichophyton indotineae is an emerging difficult to diagnose dermatophyte species associated with terbinafine resistance, which was initially described in South-Asian and Middle-Eastern countries. We report four cases of sexually transmitted dermatophytosis caused by T. indotineae in two female sex-...

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This retrospective, single-center study analyzed the clinical profile and outcomes of dematiaceous fungal infections in kidney transplant recipients over a 12-year period (2010–2022). Out of 1,041 transplant recipients, 69 developed major fungal infections, with dematiaceous fungi accounting for 8.6...

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In the current scenario, treatment of Post kala-azar dermal leishmaniasis (PKDL) is intravenous liposomal amphotericin B or oral miltefosine. Over the years, there has been a gradual decline in the efficacy of miltefosine and a rise in permanent loss of vision. Moreover, in non-endemic states of Ind...

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The classic histoplasmosis caused by Histoplasma capsulatum var. capsulatum is a systemic fungal infection primarily affecting immunocompromised patients. Although rare in India, sporadic cases have been reported from various parts of the country. The authors present a case of nodular pulmonary hist...

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<i>Trichophyton indotineae</i> is emerging globally from its origin in India, presenting with a terbinafine resistance and causing significant clinical burden. We report herein the first four confirmed cases of <i>T. indotineae</i> dermatophytoses in Malaysia, which were diag...

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El Itraconazol, un nuevo antimicótico para uso oral, fue usado en la terapia de 35 pacientes con esporotricosis cutánea y/o linfangítica, comprobadas por cultivo. En un período comprendido entre los 60 y los 150 días de terapia, desaparecieron el 91.5% de las lesiones y los cultivos se negativizaro...

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Studies of probable significance of different immunological mediators for the development of chronic allergic inflammation in patients with allergic bronchopulmonary aspergillosis (ABPA) are necessary in order to specify potential targets for therapeutic intervention and timely diagnosis of the dise...

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BackgroundEndometrial cancer (EC) is a common gynecologic malignancy with limited treatment options. This study aimed to evaluate the potential of itraconazole (ITZ), a widely used antifungal drug, as an anti-tumor agent and an adjuvant to immunotherapy for EC.MethodsThe effects of ITZ on Ishikawa c...

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Se presenta la historia de un paciente con un eumicetoma causado por Fusarium oxysporum, localizado en el pie derecho y con compromiso óseo. El paciente presentó la tríada clásica de la enfermedad: tumefacción, fistulización y presencia de gránulos. El diagnóstico se realizó mediante examen microsc...

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La onicomicosis constituye un problema terapéutico por la variación en su etiología, la dificultad en lograr niveles altos de las drogas en la lámina ungueal y la poca penetración de los tratamientos tópicos. Cono­ciendo la capacidad del itraconazol (ITZ) de permane­cer en la uña, después de suspen...

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Jijun He,&amp;ast; Jingjing Yang,&amp;ast; Zhen Liang, Zhen Zhang, Guojuan Pu, Fudan Dong, Ping Lu, Huiyun Xia, Junjie Zhang Henan Eye Hospital, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Zhengzhou, People’s Republic of China&amp;ast;These authors contrib...

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Un nuevo derivado triazólico, el itraconazol (ITZ), fue administrado a 20 pacientes con cromoblastomicosis activa debida a K pedrosoi; el fármaco se suministró en dosis de 100 - 200 mg/ día durante 19 meses en promedio. Se observó que la respuesta clínica fue macada en 11 pacientes (55%) y parcial...

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Introducción: La cromoblastomicosis (CMB) es una enfermedad fúngica granulomatosa crónica causada por la inoculación transcutánea de hongos. Sus lesiones polimórficas pueden confundirse con diversas dermatosis, tanto infecciosas como no infecciosas. Este caso se destaca por la dificultad diagnóstic...

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