Search Results - "inflammatory bowel disease"

<b>Background/Objectives:</b> Inflammatory bowel disease (IBD) includes Crohn’s disease (CD) and ulcerative colitis (UC). The availability of an increasing number of new molecules approved for IBD treatment has increased our ability and aspirations to change the trajectory of the disease...

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Inflammatory bowel disease (IBD) is a chronic disease that often has fluctuating and painful symptoms. IBD patients must cope with a lifelong illness with relapses, remissions, and varied treatments that can affect their overall quality of life. Patients living in a rural setting are faced with furt...

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Last decade heightened interest to innate immunity in different areas of medicine is observed. In article the known data for today about a role of factors of innate immunity (toll-receptors) in pathological process is reflected, the basic cascade of the reactions started by means of TLR is displayed...

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Objectives Epidemiological studies have shown an inverse association between Helicobacter pylori infection and ulcerative colitis (UC). In this study, we investigated the protective effects of H. pylori infection on the severity of UC. Methods This single-center study included 316 patients with newl...

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ABSTRACT Background and Aim A high‐fiber, low‐animal‐protein, and low‐saturated‐fat diet may modulate gut dysbiosis and benefit inflammatory bowel disease (IBD). This study investigated the effects of this diet on clinical relapses, fecal calprotectin, and gut microbiota in patients with clinically...

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Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic, immune-mediated inflammatory disorder of the gastrointestinal tract. Immunosuppressive therapy administration increases the risk of hepatitis B virus (HBV) and hepatitis C virus (HCV) reactiv...

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Cytomegalovirus (CMV) colitis, a complication in patients with inflammatory bowel disease (IBD), particularly ulcerative colitis (UC), is a significant diagnostic and therapeutic challenge due to its overlap with IBD flares. CMV reactivation in IBD is driven by chronic inflammation, compromised immu...

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<b>Background/Objectives</b>: Patients with inflammatory bowel disease (IBD) are at an increased risk of various cancers; such as colorectal cancer; skin cancer; bile duct cancer; or lymphoma; with IBD itself not being the sole cause. Inappropriate or ineffective IBD therapy with a conti...

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[Introduction] Anti-tumour necrosis factor (TNF) therapy has greatly improved treatment outcomes in patients with inflammatory bowel disease (IBD), but long-term use is associated with cutaneous reactions, susceptibility to infections and frequent injections or hospital visits. Several non-controlle...

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Introduction/Objective Inflammatory bowel disease (IBD) is often diagnosed during sexually active years, and factors like disease severity, treatment, and surgery may impact sexual function. This study aims to assess sexual quality of life in IBD patients. Methods Patients with IBD and cont...

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Inflammatory bowel disease (IBD) is a chronic disease that is influenced by a variety of factors, including genetics, environment and gut microbiota. In recent years, with the gradual deepening of IBD understanding, it has been discovered that changes in the gut microenvironment may play indispensab...

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Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by the relapsing inflammation of the colonic mucosa. Corticosteroids have long been a cornerstone in the management of moderate to severe UC, particularly during acute flares. This review aims to provide a focused overview...

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Mechanisms of recognition and effector responses of immune system upon initiation and maintenance of immune-mediated inflammation and tissue damage in inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis (UC), have been actively studied over recent time. Existing evidence su...

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Autophagy, a highly conserved cellular degradation pathway promotes cell survival via lysosomal degradation of aberrant cellular proteins and recycling of the nutrients. A variety of human diseases are now linked to defective autophagy and there is ever-growing interest in the application of autopha...

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Background. The first scientific description of inflammatory bowel disease refers to the pathologoanatomic work of Samuel Wilkes. This sectional research is related to a real detective story, which had a great public response in Victorian England. The story focuses on the death of Isabella Banks, wh...

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<b>Introduction:</b> In the general population, right I-sided dysplasia presents a higher risk for colorectal cancer (CRC) and metachronous dysplasia compared to left (L)-sided dysplasia. Given that patients with inflammatory bowel disease (IBD) are at higher risk for dysplasia than the...

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ABSTRACT Aims To provide an understanding of the sexual and reproductive health issues for women who live with inflammatory bowel disease. Design Whittemore and Knaffle's integrative review. Methods Databases searched in this integrative review included: CINAHL Plus, Google Scholar, SCOPUS and...

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Fen-Ying Lu, Xia Huang, Ke Zhang, Xin Yin, Yang Lv, Yue-Chen Du, Qian Zhou, Jing-Yu Min, Cui-E Cheng Department of Gastroenterology, Affiliated Changshu Hospital of Nantong University (Changshu No. 2 People’s Hospital), Changshu, People’s Republic of ChinaCorrespondence: Cui-E Cheng, Email Cuie_chen...

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Nowadays, an urgent problem of pediatric gastroenterology is the study of inflammatory bowel diseases with very early onset (VEO-IBD), which have unique genetic, clinical, immunological, morphological, and laboratory sings. Early VEO-IBD is usually considered as monogenic disease, especially in comb...

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