Search Results - "inflammation"

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  1. 1

    Obesity = inflammation. Pathogenesis. How does this threaten men? by Z. Sh. Pavlova, I. I. Golodnikov

    Published 2020-12-01

    Today, adipose tissue has ceased to be perceived only as an energetic substance with its intrinsic properties in the form of thermoregulation and mechanical protection, known since the beginning of the twentieth century. Today, adipose tissue is a fullfledged endocrine organ that is distributed thro...

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  2. 2

    In regards to lipoxins as lipid mediators for the resolution of inflammation using the example of asthma by O. Yu. Kytikova, T. P. Novgorodtseva, I. S. Kovalenko

    Published 2025-03-01

    Asthma is the most important medical and social problem of our time due to its widespread prevalence, chronic course and heterogeneity, which determines the complexity of  treating this disease. Chronic inflammation, characteristic of  asthma, is accompanied by the development of an imbalance betwee...

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  3. 3

    Integrated Assessment of the Anti-Inflammatory Effect <i>in Vivo</i> of Aqueous Extracts and Gels Based on Black Alder and Gray Alder Leaves by O. V. Mushkina, N. S. Gurina

    Published 2025-07-01

    INTRODUCTION. Flavonoids contained in many plant species inhibit the induction of cytokines and arachidonic acid metabolites, which are tissue mediators of inflammation, thus exhibiting an anti-inflammatory effect. The leaves of black and gray alder contain flavonoids, phenolic carboxylic acids, tan...

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  4. 4

    ASSESSMENT OF SYSTEMIC INFLAMMATORY REACTION IN ACUTE MYOCARDIAL INFARCTION: STATUS UPDATE ON THE PROBLEM by M. A Kachkovsky, E. Yu. Ragozinа

    Published 2015-09-01

    Analysis of the data of national and international researches on evaluation of systemic inflammation in the acute coronary syndrome over the last 10 years was carried out. The problems of application the most studied inflammation markers in patients with acute myocardial infarction in clinical pract...

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  5. 5

    Targeted Biologic Therapies in Severe Asthma: Mechanisms, Biomarkers, and Clinical Applications by Renata Maria Văruț, Dop Dalia, Kristina Radivojevic, Diana Maria Trasca, George-Alin Stoica, Niculescu Stefan Adrian, Niculescu Elena Carmen, Cristina Elena Singer

    Published 2025-07-01

    Asthma represents a heterogeneous disorder characterized by a dynamic balance between pro-inflammatory and anti-inflammatory forces, with allergic sensitization contributing substantially to airway hyperresponsiveness and remodeling. Central to its pathogenesis are cytokines such as IL-4, IL-5, IL-1...

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    Subjects: “…airway inflammation…”
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  6. 6

    Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy by Tyler C. Hillman, Tyler C. Hillman, Braeden Jacobson, Kiara Piaggio Hurtado De Medoza, Marlene Lopez, Nicholas Iwakoshi, Christopher G. Wilson, Christopher G. Wilson, Christopher G. Wilson

    Published 2025-07-01

    IntroductionPreterm hypoxic-ischemic encephalopathy (pHIE) is a complex brain injury that contributes to chronic neural inflammation and neurological disorders. The signs and symptoms of in utero pHIE can often be overlooked, untreated or lumped into more generic conditions such as encephalopathy of...

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  7. 7

    The role of inflammatory theory in the pathogenesis of atrial fibrillation by K. V. Davtyan, A. A. Kalemberg, E. N. Tsareva, O. V. Blagova, M. S. Harlap

    Published 2019-08-01

    Based on the data available in the literature, it is obvious that inflammation plays a significant role in the initiation, support and progression of AF. However, it is important that AF by itself is a factor provoking the development of inflammation in the atrial myocardium, which leads to the furt...

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  8. 8

    Prospective study of inflammatory response in patients submitted to abdominoplasty after bariatric surgery by Nádia de Rosso Giuliani, Miguel Modolin, Wilson Cintra, Rodrigo Itocazo Rocha, Rolf Gemperli

    Published 2021-06-01

    Introduction: Obesity is a chronic inflammatory disease associated with changes in inflammatory markers such as interleukins and CRP. This study evaluates the inflammatory response, through variations in interleukins and CRP, in patients undergoing abdominoplasty. Methods: Fourteen patie...

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  9. 9

    Association of advanced lung cancer inflammation index with all-cause and cardiovascular mortality in US patients with asthma by Jiatao Li, Huanhuan Liu, Bin Xu

    Published 2025-06-01

    BackgroundAsthma poses a significant global health challenge, representing a chronic respiratory disorder marked by airway inflammation. The advanced lung cancer inflammation index (ALI) served as a comprehensive index to assess inflammation. However, few studies have investigated the association be...

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  10. 10

    DIAGNOSTIC SIGNIFICANCE OF LOCAL ALTERATIONS OF BRONCHIAL TREE IN THE COMPREHENSIVE SURVEY OF PATIENTS WITH PULMONARY TUBERCULOSIS by O. A. Serov, T. A. Kolpakova, V. A. Krasnov

    Published 2013-02-01

    The difficulties in the interpretation of identified during bronchoscopy local bronchi alterations in patients with pulmonary tuberculosis make this problem of current interest. The comprehensive survey of 287 patients revealed the specific origin of local alterations of bronchial tree in 50% of pat...

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  11. 11

    Increased inflammation burden index increasing the risk of poor prognosis in patients with chronic kidney disease in NHANES study by Xinhao Chen, Dongming Ye, Weijie Zhou, Ziyi Huang, Wanwen Zou, Rongjun Zeng, Wenyong Chen

    Published 2025-12-01

    Objective Several studies illustrated high level of inflammation is an important factor affecting the poor prognosis of patients with chronic kidney disease. Inflammatory burden index (IBI) is a composite maker by incorporating a variety of inflammatory markers to facilitate more in-depth assessment...

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    Subjects: “…Inflammation burden index…”
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  12. 12

    Predictive value of pan-immune-inflammation value in the prognosis of adults with status epilepticus: a retrospective study by Jie Fu, Yifei Chu, Chenxin Zhao, Lilei Peng

    Published 2025-07-01

    ObjectiveTo investigate the predictive capacity of the pan-immune-inflammation value (PIV) for functional outcomes in patients with status epilepticus (SE).MethodsIn this study, we investigated and confirmed the prognostic significance of PIV in adult patients with SE. Clinical information and labor...

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  13. 13

    Inflammation markers in atherosclerosis development by A. P. Shavrin, Ya. B. Khovaeva, V. A. Chereshnev, B. V. Golovskoy

    Published 2009-06-01

    Aim. To study different inflammation markers at various stages of atherosclerosis progression.Material and methods. In 174 21-70-year-old people, brachial artery ultrasound (Aloka 5000) was performed to visualize atherosclerotic plaques and assess intima-media thickness (IMT). Immuno-enzyme analysis...

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  14. 14

    TREATMENT OF EXPERIMENTAL PERIODONTITIS BY TERPENE-CONTAINING MEDICATION by M. V. Dudar, L. S. Vasilyeva, V. D. Molokov

    Published 2014-11-01

    Therapeutic effect of terpenoidisobornylacetate-containing preparation Antiran on the inflammatory process in paradontium in 56 white outbread rats was researched. Animals of control group wasn't provide the treatment, animals of treatment group had antibiotic dialysis from 1st till 3rd day, ul...

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  15. 15

    Clinical estimation of efficiency of application of terpene-containing preparation in complex treatment of chronic generalized parodontitis by M. V. Dudar, V. D. Molokov, O. I. Tirskaya, T. K. Shkavro, L. R. Kolesnikova

    Published 2017-09-01

    The article presents the comparative analysis of application of terpene-containing medicine Antiran (1:3 solution) and 0.06% chlorhexidine bigluconate solution in a complex therapy of patients with chronic generalized parodontitis. According to the curative effect, these drugs are comparable with an...

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  16. 16

    Pregnancy urinary phenol biomarker concentrations in relation to serum levels of inflammatory cytokines: Results from the EARTH study by Xinxiu Liang, Sarah Grill, Xilin Shen, Paige L. Williams, Tamarra James-Todd, Jennifer B. Ford, Kathryn M. Rexrode, Antonia M. Calafat, Jorge E. Chavarro, Russ Hauser, Lidia Mínguez-Alarcón

    Published 2025-08-01

    Background: Evidence on the association between maternal phenol exposure and inflammation during pregnancy is limited and inconsistent. Objective: To evaluate associations between urinary phenol biomarkers and serum inflammatory cytokines across pregnancy, and to examine whether associations vary by...

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  17. 17

    FEATURES OF CYTOKINE-MEDIATED REGULATION OF FOCAL AND SYSTEMIC INFLAMMATION IN COPD by E. A. Surkova, N. A. Kuzubova, T. P. Ses’, Areg A. Totolian

    Published 2014-07-01

    Chronic obstructive pulmonary disease (COPD) is associated with pulmonary and systemic inflammation. The latter is likely to contribute significantly to the pathobiology of numerous extrapulmonary effects of the disease, i.e., systemic effects of COPD. The main causes of systemic inflammation in COP...

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  18. 18

    Effect of Sevoflurane on Activation of Human Neutrophiles in Ex Vivo Models by D. O. Starostin, A. N. Kuzovlev, O. A. Grebenchikov, V. T. Dolgikh

    Published 2022-02-01

    The objective is to study the effect of different concentrations of sevoflurane on activation of human neutrophils in an ex vivo model.Subjects and Methods. The cell culture of venous blood neutrophils of 5 healthy men was used in this study. Neutrophil activation by lipopolysaccharide (LPS) and che...

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    Subjects: “…inflammation, neutrophils, sevoflurane…”
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  19. 19

    Neurogenic inflammation: biochemical markers, genetic control and diseases by A. N. Kucher

    Published 2020-07-01

    Neurogenic inflammation is a pathological process based on bidirectional interactions between cells of the nervous and immune systems as well as on a wide range of biologically active substances.Aim. Basing on scientific publications and information provided in databases, to analyze markers of neuro...

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    Subjects: “…neurogenic inflammation…”
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  20. 20

    HDL apoprotein immunization induces T cell-mediated venulitis and inflammation in aorta by А. Yu. Sidorov, K. V. Fomina, L. V. Beduleva

    Published 2023-06-01

    The hypothesis that atherosclerotic processes are mostly caused by immune (autoimmune) mechanisms has recently been gaining attraction. At the same time, the autoimmune hypothesis of atherogenesis has not become generally accepted and requires additional evidence. Previously, we were able to induce...

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    Subjects: “…vascular inflammation…”
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