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Obesity = inflammation. Pathogenesis. How does this threaten men?
Published 2020-12-01Subjects: Get full textToday, adipose tissue has ceased to be perceived only as an energetic substance with its intrinsic properties in the form of thermoregulation and mechanical protection, known since the beginning of the twentieth century. Today, adipose tissue is a fullfledged endocrine organ that is distributed thro...
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In regards to lipoxins as lipid mediators for the resolution of inflammation using the example of asthma
Published 2025-03-01Subjects: Get full textAsthma is the most important medical and social problem of our time due to its widespread prevalence, chronic course and heterogeneity, which determines the complexity of treating this disease. Chronic inflammation, characteristic of asthma, is accompanied by the development of an imbalance betwee...
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Integrated Assessment of the Anti-Inflammatory Effect <i>in Vivo</i> of Aqueous Extracts and Gels Based on Black Alder and Gray Alder Leaves
Published 2025-07-01Subjects: “…inflammation…”INTRODUCTION. Flavonoids contained in many plant species inhibit the induction of cytokines and arachidonic acid metabolites, which are tissue mediators of inflammation, thus exhibiting an anti-inflammatory effect. The leaves of black and gray alder contain flavonoids, phenolic carboxylic acids, tan...
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ASSESSMENT OF SYSTEMIC INFLAMMATORY REACTION IN ACUTE MYOCARDIAL INFARCTION: STATUS UPDATE ON THE PROBLEM
Published 2015-09-01Subjects: Get full textAnalysis of the data of national and international researches on evaluation of systemic inflammation in the acute coronary syndrome over the last 10 years was carried out. The problems of application the most studied inflammation markers in patients with acute myocardial infarction in clinical pract...
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Targeted Biologic Therapies in Severe Asthma: Mechanisms, Biomarkers, and Clinical Applications
Published 2025-07-01Subjects: “…airway inflammation…”Asthma represents a heterogeneous disorder characterized by a dynamic balance between pro-inflammatory and anti-inflammatory forces, with allergic sensitization contributing substantially to airway hyperresponsiveness and remodeling. Central to its pathogenesis are cytokines such as IL-4, IL-5, IL-1...
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Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy
Published 2025-07-01Subjects: Get full textIntroductionPreterm hypoxic-ischemic encephalopathy (pHIE) is a complex brain injury that contributes to chronic neural inflammation and neurological disorders. The signs and symptoms of in utero pHIE can often be overlooked, untreated or lumped into more generic conditions such as encephalopathy of...
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The role of inflammatory theory in the pathogenesis of atrial fibrillation
Published 2019-08-01Subjects: Get full textBased on the data available in the literature, it is obvious that inflammation plays a significant role in the initiation, support and progression of AF. However, it is important that AF by itself is a factor provoking the development of inflammation in the atrial myocardium, which leads to the furt...
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Prospective study of inflammatory response in patients submitted to abdominoplasty after bariatric surgery
Published 2021-06-01Subjects: Get full textIntroduction: Obesity is a chronic inflammatory disease associated with changes in inflammatory markers such as interleukins and CRP. This study evaluates the inflammatory response, through variations in interleukins and CRP, in patients undergoing abdominoplasty. Methods: Fourteen patie...
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Association of advanced lung cancer inflammation index with all-cause and cardiovascular mortality in US patients with asthma
Published 2025-06-01Subjects: Get full textBackgroundAsthma poses a significant global health challenge, representing a chronic respiratory disorder marked by airway inflammation. The advanced lung cancer inflammation index (ALI) served as a comprehensive index to assess inflammation. However, few studies have investigated the association be...
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DIAGNOSTIC SIGNIFICANCE OF LOCAL ALTERATIONS OF BRONCHIAL TREE IN THE COMPREHENSIVE SURVEY OF PATIENTS WITH PULMONARY TUBERCULOSIS
Published 2013-02-01Subjects: Get full textThe difficulties in the interpretation of identified during bronchoscopy local bronchi alterations in patients with pulmonary tuberculosis make this problem of current interest. The comprehensive survey of 287 patients revealed the specific origin of local alterations of bronchial tree in 50% of pat...
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Increased inflammation burden index increasing the risk of poor prognosis in patients with chronic kidney disease in NHANES study
Published 2025-12-01Subjects: “…Inflammation burden index…”Objective Several studies illustrated high level of inflammation is an important factor affecting the poor prognosis of patients with chronic kidney disease. Inflammatory burden index (IBI) is a composite maker by incorporating a variety of inflammatory markers to facilitate more in-depth assessment...
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Predictive value of pan-immune-inflammation value in the prognosis of adults with status epilepticus: a retrospective study
Published 2025-07-01Subjects: Get full textObjectiveTo investigate the predictive capacity of the pan-immune-inflammation value (PIV) for functional outcomes in patients with status epilepticus (SE).MethodsIn this study, we investigated and confirmed the prognostic significance of PIV in adult patients with SE. Clinical information and labor...
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Inflammation markers in atherosclerosis development
Published 2009-06-01Subjects: Get full textAim. To study different inflammation markers at various stages of atherosclerosis progression.Material and methods. In 174 21-70-year-old people, brachial artery ultrasound (Aloka 5000) was performed to visualize atherosclerotic plaques and assess intima-media thickness (IMT). Immuno-enzyme analysis...
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TREATMENT OF EXPERIMENTAL PERIODONTITIS BY TERPENE-CONTAINING MEDICATION
Published 2014-11-01Subjects: Get full textTherapeutic effect of terpenoidisobornylacetate-containing preparation Antiran on the inflammatory process in paradontium in 56 white outbread rats was researched. Animals of control group wasn't provide the treatment, animals of treatment group had antibiotic dialysis from 1st till 3rd day, ul...
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Clinical estimation of efficiency of application of terpene-containing preparation in complex treatment of chronic generalized parodontitis
Published 2017-09-01Subjects: Get full textThe article presents the comparative analysis of application of terpene-containing medicine Antiran (1:3 solution) and 0.06% chlorhexidine bigluconate solution in a complex therapy of patients with chronic generalized parodontitis. According to the curative effect, these drugs are comparable with an...
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Pregnancy urinary phenol biomarker concentrations in relation to serum levels of inflammatory cytokines: Results from the EARTH study
Published 2025-08-01Subjects: Get full textBackground: Evidence on the association between maternal phenol exposure and inflammation during pregnancy is limited and inconsistent. Objective: To evaluate associations between urinary phenol biomarkers and serum inflammatory cytokines across pregnancy, and to examine whether associations vary by...
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FEATURES OF CYTOKINE-MEDIATED REGULATION OF FOCAL AND SYSTEMIC INFLAMMATION IN COPD
Published 2014-07-01Subjects: Get full textChronic obstructive pulmonary disease (COPD) is associated with pulmonary and systemic inflammation. The latter is likely to contribute significantly to the pathobiology of numerous extrapulmonary effects of the disease, i.e., systemic effects of COPD. The main causes of systemic inflammation in COP...
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Effect of Sevoflurane on Activation of Human Neutrophiles in Ex Vivo Models
Published 2022-02-01Subjects: “…inflammation, neutrophils, sevoflurane…”The objective is to study the effect of different concentrations of sevoflurane on activation of human neutrophils in an ex vivo model.Subjects and Methods. The cell culture of venous blood neutrophils of 5 healthy men was used in this study. Neutrophil activation by lipopolysaccharide (LPS) and che...
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Neurogenic inflammation: biochemical markers, genetic control and diseases
Published 2020-07-01Subjects: “…neurogenic inflammation…”Neurogenic inflammation is a pathological process based on bidirectional interactions between cells of the nervous and immune systems as well as on a wide range of biologically active substances.Aim. Basing on scientific publications and information provided in databases, to analyze markers of neuro...
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HDL apoprotein immunization induces T cell-mediated venulitis and inflammation in aorta
Published 2023-06-01Subjects: “…vascular inflammation…”The hypothesis that atherosclerotic processes are mostly caused by immune (autoimmune) mechanisms has recently been gaining attraction. At the same time, the autoimmune hypothesis of atherogenesis has not become generally accepted and requires additional evidence. Previously, we were able to induce...
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