Search Results - "exacerbations"

Background and Objective: Eosinophils are an integral part of lung defence against microbes. It is also responsible for untoward hyper immune responses responsible for lung diseases including Chronic Obstructive Pulmonary Disease (COPD). To compare COPD patients with high and low Absolute Eosinophil...

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In the structure of infant morbidity acute and chronic inflammatory diseases of the oropharynx take a leading position. Finding the most effective approaches to the treatment and prevention of diseases in this group so far has not lost its relevance. Drugs containing lysates of bacteria are currentl...

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Summary: Background: Health inequalities are deeply entrenched in society, and finding ways to reduce these, therefore, represents a major health policy challenge. Focusing on the two highest weighted Index of Multiple Deprivation domains, namely income and employment, we sought to synthesise the e...

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Charlotte Hyldgaard,1,2 Thomas Ringbæk,3 Frank Dyekjær Andersen,1 Ejvind Frausing Hansen,4 Michael Skov Jensen,1 Morten Fenger-Grøn,1 Christian Trolle,1,2 Charlotte Suppli Ulrik4,5 1Medical Diagnostic Center, University Clinic for Innovative Patient Pathways, Regional Hospital Central Jutland, Silke...

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We investigated the effectiveness of Copaxone in patients with relapsing-remitting multiple sclerosis for 3 and 5 years. Significant improvement found the decrease of the frequency of clinical exacerbations and delay the accumulation of physical disability during treatment period.

Introduction: Traffic-Related Air Pollution (TRAP) is currently among the priority environmental issues because of the strong correlation it shares with the occurrence of unwanted respiratory effects, particularly in children. Air pollution exposure to pollutants such as Nitrogen dioxide (NO₂) and...

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Frida Vilstrup,1 Pradeesh Sivapalan,1,2 Josefin Eklöf,1 Alexander Jordan,1 Tor Biering-Sørensen,3,4 Søren Sperling,5 Jens-Ulrik Stæhr Jensen1,2 1Department of Medicine, Section of Respiratory Medicine, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, 2900, Denmark; 2Department of Cl...

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Asthma represents a heterogeneous disorder characterized by a dynamic balance between pro-inflammatory and anti-inflammatory forces, with allergic sensitization contributing substantially to airway hyperresponsiveness and remodeling. Central to its pathogenesis are cytokines such as IL-4, IL-5, IL-1...

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Severe asthma exacerbations have high morbidity and mortality. The management can be challenging, and the optimal strategy for patients admitted to the intensive care unit (ICU) with life-threatening and near-fatal asthma has not been fully defined. An interesting area of research is represented by...

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Background: Smoking-induced Chronic obstructive pulmonary disease (COPD) is a chronic lung condition causing airflow obstruction and inflammation, leading to symptoms like breathlessness and fatigue. While expiratory issues are well-studied, the impact of inspiratory function on symptoms is less un...

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Claus F Vogelmeier,1 Felix W Friedrich,2 Patrick Timpel,3 Nils Kossack,3 Joanna Diesing,3 Marc Pignot,4 Melanie Abram,2 Michael Gediga,2 Marija Halbach2 1Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-Universität Marburg, German...

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Background: Smoking-induced Chronic obstructive pulmonary disease (COPD) is a chronic lung condition causing airflow obstruction and inflammation, leading to symptoms like breathlessness and fatigue. While expiratory issues are well-studied, the impact of inspiratory function on symptoms is less un...

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Background. Etanercept is a biological drug most commonly used in patients with juvenile idiopathic arthritis (JIA). The results of its use are showed in local studies.Objective. Our aim was to evaluate the efficacy and safety of the use of etanercept in children with non-systemic JIA, to determine...

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Background: Asthma exacerbations are episodes of symptom worsening requiring increased therapy, which affect patients across all asthma severities. Potential genetic associations with asthma exacerbations in an understudied population were investigated. Objective: We sought to perform a genome-wide...

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Background Chronic obstructive pulmonary disease exacerbations (acute exacerbation of chronic obstructive pulmonary disease) are characterised by increased sputum volume, purulence and breathlessness. Patients are encouraged to recognise and treat acute exacerbation of chronic obstructive pulmonary...

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Objective: Chronic obstructive pulmonary disease is currently the third leading cause of death worldwide. The current study was designed to see if fibrinogen, interleukin-6 or surfactant protein-D could be used as biomarkers to predict frequency of exacerbations within the frequent exacerbator phen...

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Objective: Chronic obstructive pulmonary disease is currently the third leading cause of death worldwide. The current study was designed to see if fibrinogen, interleukin-6 or surfactant protein-D could be used as biomarkers to predict frequency of exacerbations within the frequent exacerbator phen...

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Introduction: The relationship between asthma and obesity is complex and multifactorial. Obesity is a risk factor for asthma and is associated with more severe disease, poor response to treatment, and more frequent exacerbations. Bariatric surgery is the most effective way to lose weight. Several...

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Samy Suissa,1– 3 Sophie Dell’Aniello,1 Michael Andrew Webster-Clark,1,2 Pierre Ernst1– 3 1Centre for Clinical Epidemiology, Lady Davis Institute-Jewish General Hospital, Montreal, QC, Canada; 2Department of Medicine, McGill University, Montreal, QC, Canada; 3Department of Epidemiology, Biostatistics...

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Wei Wei An, Le Ting Zheng, Fei Dong, Xiao Ning Zhong Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning City, People’s Republic of ChinaCorrespondence: Xiao Ning Zhong, Department of Respiratory and Critical Care Medicine, The F...

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