Search Results - "comorbidities"

Objective: to study the rate and pattern of comorbidities in two groups of patients with rheumatoid arthritis (RA) in different follow-up years.Subjects and methods. The pattern of comorbidity was investigated in RA patients treated at the Rheumatology Unit, Saratov Regional Clinical Hospital, in di...

Full description

This article provides an overview of the existing literature on the pharmacogenetic determinants of exposure and toxicity of antiretroviral drugs, as well as on genetic markers associated with the rate of disease progression. In addition, this article looks at current clinical opportunities as well...

Full description

ABSTRACT Objective Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder. However, no causal link has been established i...

Full description

Generalized secondary peritonitis is a life-threatening intra-abdominal infection requiring urgent surgical intervention. Despite advances in surgical and antimicrobial therapy, morbidity and mortality remain high. Identifying key prognostic factors is crucial for improving patient outcomes. This re...

Full description

Routine pediatric vaccinations have resulted in dramatic declines in the incidence and complications of several vaccine-preventable diseases (VPDs) over the past fifty years. At the same time, the prolongation of life expectancy and the large number of adults living with chronic medical conditions c...

Full description

Objective: to evaluate the efficacy and safety of glycosaminoglycan-peptide complex (GPC, Rumalon) used in patients with knee osteoarthritis (OA) and comorbidities (hypertension and/or type 2 diabetes mellitus (T2DM).Patients and methods: A 10-month multicenter (13 centers from 10 subjects of the Ru...

Full description

Background. With the increased use of combination antiretroviral therapy, the mortality of people living with HIV has decreased significantly, which has led to an increase of comorbidity and secondary HIV-related pathology in both adults and also in children and adolescents living with HIV infection...

Full description

Introduction: The association of chondrodermatitis nodularis (CN) with diseases of vascular injury, tobacco smoking, and diabetes mellitus has been separately reported in patients with an early onset of lesions.  Objectives: We aimed to expand and deepen previous studies and to investigate 8 como...

Full description

Introduction: Migraines are a prevalent neurovascular disorder that affects more than a billion people worldwide. Even though both women and men are affected by this neurological disorder, migraines are primarily recognized as a women’s health disruption factor. Pregnancy leads to significant hormon...

Full description

Background. The problem of comorbidity in ischemic heart disease (IHD) has always been given increased attention, due to the high social significance of cardiovascular diseases. However, often the problem solution involved studying cardiac pathology along with concomitant diseases, such as diabetes...

Full description

Abstract Stroke, a leading cause of mortality and morbidity worldwide, is a complex cerebrovascular disease. Stroke risk factors are diverse, encompassing age, sex, and ethnicity. Comorbid conditions, including hypertension, hyperglycemia, hyperlipidemia, and atrial fibrillation, exacerbate stroke o...

Full description

The literature review presents the current idea about the mechanisms of chronic pain. Experimental and clinical studies of the mechanism of chronic pain in osteoarthrosis (OA), which show that dysfunction of pain systems themselves (the so-called dysfunctional pain) along with the nociceptive mechan...

Full description

A study which included 97 children who had COVID-19 during the period from September 2021 to January 2022 was conducted. This article discusses the symptoms occurring after COVID-19 infection. The analysis of the results showed that the largest proportion among sick children was in patients with red...

Full description

ABSTRACT Background Due to its rarity, there are very limited data available on the cause of death (COD) and its association with comorbidities in Japanese chronic lymphocytic leukemia (CLL) patients. Methods To investigate the prevalence of comorbidities and their impact on cause‐specific mortality...

Full description

Objective: To evaluate the complications, outcomes, and development of chronic diseases in patients following COVID-19-related acute respiratory distress syndrome (ARDS) with diffuse alveolar damage of varying severity in patients with and without initial comorbidities. Methods: A retrospective a...

Full description

Background Psoriasis is frequently associated with non-communicable disease (NCD) comorbidities, prompting interest in how these concurrent conditions may influence psoriasis treatment outcomes.Objectives To assess NCD prevalence and their influence on psoriasis treatment outcomes.Methods From 2022...

Full description

The objective of the study was to describe patients with HIV infection, who were diagnosed in 2016 in St Petersburg AIDS Center, including provided antiretroviral therapy (ART).A retrospective review of 521 patients’ case histories was performed. The case history selection was done by random samplin...

Full description

BackgroundNarcolepsy is a rare neurological cause of chronic sleepiness. This study aimed to better understand global narcolepsy through bibliometric analysis.MethodsArticles and reviews on narcolepsy were sourced from the Web of Science Core Collection. A bibliometric analysis was performed using M...

Full description