Search Results - "chromosome"

For the first time in the present resort chromosome set and some problems of Canis aureus ecology is described taking into account the structure of hail high altitude zone of mountain ecosystem.

Bimodal karyotypes, initially defined by Avdulov, are characterized by one large and one small set of chromosomes, reflecting a particular type of karyotype asymmetry. Despite later discussions by Stebbins, the absence of a quantitative criterion has led to subjective classifications. This study rev...

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Insects play an indispensable role in ecosystems, and studies on their chromosome evolution are crucial for understanding mechanisms of speciation, trait evolution and environmental adaptation. This paper systematically summarized the research progress in the field of insect chromosome evolution, fo...

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Williams syndrome (WS), also known as Williams-Beuren syndrome, is an autosomal dominant disorder. Although the exact incidence is unknown, it is estimated to occur in approximately 1 in 20,000 live births. The syndrome has been identified in all ethnic groups worldwide and affects both sexes equall...

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Objective of the study was to review the anamnesis, pheno - and genotype in patients with rare chromosome disorders such as 9p deletion syndrome. Genetic methods of investigation (clinical and genealogical, cytogenetic, FISH- method), paraclinical and instrumental methods of examination were used. K...

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Application of microdissected DNA libraries and DNA probes in numerous and various modern molecular cytogenetic studies showed them as an efficient and reliable tool in the analysis of chromosome reorganization during karyotypic evolution and in the diagnosis of human chromosome pathology. An import...

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The incidence and mortality of malignant neoplasms of non-reproductive organs both carcinomas and sarcomas in men is one and a half times higher than in women. This is based on genetic differences, which are superimposed by patterns of epigenetic regulation of the expression of sex chromosome genes...

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Basic chromosome numbers are compared among species of four gymnosperm divisions, three Anthophyta families, and three Mammalia subclasses, with different life cycle types. Gymnosperm and angiosperm species characterized by alternation of haploid and diploid phases, sporic meiotic reduction, hermaph...

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One of the most productive strategies for finding the functions of proteins is to study the consequences of loss of protein function. For this purpose, cells or organisms with a knockout of the gene encoding the protein of interest are obtained. However, many proteins perform important functions and...

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Kinship analyses unlock the power of genetic data to unravel biological relationships and identify individuals. While most cases involve paternity/maternity problems using autosomal markers, more challenges arise when more complex kinship cases are investigated or when the information given by auto...

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Atrial fibrillation (AF) is the commonest type of arrhythmia seen in everyday clinical practice, which leads to a significant increase in both morbidity and mortality. Its incidence increases with age and tends to turn into an epidemic. The cause of AF in 10-20% of cases remains unknown. Several mut...

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We report a case of a girl with a chromosomal disorder that has never been described in the literature: inversion of chromosome 4 with an unbalanced translocation between the short arm of chromosome 4 and long arm of chromosome 18. Clinical manifestations of this syndrome included severe growth reta...

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The cytogenetic relationships in the species of Cucurbitaceae are becoming immensely important to answer questions pertaining to genome evolution. Here, a simplified and updated data resource on cytogenetics of Cucurbitaceae is presented on the basis of foundational parameters (basic, zygotic and ga...

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Cytogenetic changes in bone marrow cells and their influence on clinical course of the disease were analyzed in 106 patients with acute non-lymphoblastic leukemia (ANLL). According to rearrangements of chromosomes the patients were divided into three groups. The first group consisted of patients wit...

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Microsatellites or short tandem repeats (STRs) are the most used markers in population and forensic genetics due to their high polymorphism that is consequence of high germinal mutation rates. Mutation modeling has been a topic of intense research as its proper estimation is crucial for a wide rang...

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Cytological study in four species of Colocasia (Araceae) of Assam showed a variation of chromosome numbers. Basic chromosome number of the species was reported as n= 14. Dominance of metacentric chromosomes in all the four species and symmetric karyotypes indicate the primitive evolutionary status...

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The formation of interphase chromosomes is a multi-level process in which DNA is compacted several thousandfold by association with histones and non-histone proteins. The first step of compaction includes the formation of nucleosomes – the basic repeating units of chromatin. Further packaging occurs...

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Aim. Detection of chromosomal aberrations in patients during spontaneous abortion. Methods and results. Cytogenetic study of chorionic samples of the abortions on first trimester of pregnancy. According to the study, the karyotype anomalies were the cause of cardiac embryonic development in 59% o...

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Two cases of epilepsy in patients with a rare hereditary pathology associated with a chromosomal mutation caused deletion of chromosome 14 are presented. In the first case, this pathology was manifested in the child by generalized tonic-clonic seizures, delayed psycho-verbal development, and facial...

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