Search Results - "autoantibodies"

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  1. 1

    AUTOANTIBODIES IN SYSTEMIC SCLEROSIS: SPECTRUM, CLINICAL ASSOCIATIONS, AND PROGNOSTIC VALUE by L. P. Ananyeva, E. N. Aleksandrova

    Published 2016-03-01

    The purpose of the review is to clinically evaluate circulating autoantibodies in systemic sclerosis (SS). The diseasespecific, i.e. disease-associated, antinuclear autoantibodies: to centromeres, to topoisomerase 1; a group of antinuclear antibodies to ribonucleoprotease III, Th/T0, Pm/Scl, as well...

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  2. 2

    Autoimmune Hepatitis in Children: The Current State of the Problem by G. V. Volynets, A. I. Khavkin, T. A. Skvortsova, V. V. Matkash

    Published 2018-11-01

    Aim. To generalize the results of existing research studies carried out to investigate autoimmune hepatitis (AIH) in children, and the contemporary approaches to the diagnosis and therapy of the disease. Key points. According to the results of serological studies, two types of AIH can be distinguish...

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  3. 3

    APPLICATION OF DIFFERENT LABORATORY METHODS FOR ANTINUCLEAR AUTOANTIBODIES INVESTIGATION IN PATIENTS WITH AUTOIMMUNE CONNECTIVE TISSUE DISEASES by I. A. Pashnina, I. M. Krivolapova, I. A. Tuzankina, V. A. Chereshnev

    Published 2012-05-01

    1222 patients with suspicion of different autoimmune connective tissue diseases are investigated. Antinuclear antibodies by indirect immunofluorescence reaction, by methods of ELISA and immunoblotting were determined. Laboratory tests results correlated with each other that testifies to satisfactory...

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  4. 4

    ASSESSMENTS OF AUTOANTIBODY AND CYTOKINE CONTENTS IN TEENAGERS OF INDUSTRIAL CENTERS SCREENING EXAMINATION by L. B. Masnaviyeva, I. V. Kudayeva

    Published 2012-05-01

    270 teenagers without acute inflammation signs at the moment of the examination living in the industrial centers of Eastern Siberia have been examined. The declinations from the reference levels of the relative autoantibody content to native DNA were found to observe in 23.5 %, to β2-glycoprotein I...

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  5. 5

    Features of the functioning of the innate and adaptive immunity system in patients with COVID-19 of the older age group by O. N. Scheglovitova, L. V. Kolobukhina, A. A. Babayants, I. S. Frolova, E. I. Isaeva, I. S. Kruzhkova, A. A. Samkov, N. A. Antipyat, I. N. Tyurin, A. N. Narovliansky, F. I. Ershov

    Published 2023-10-01

    Goal. Characteristics of innate, cellular and adaptive immunity in patients of the older age group with COVID19.Materials and methods. Blood leukocytes were induced by Newcastle disease virus (α-interferon), phytohemagglutinin (γ-interferon), SARS CoV 2: RBD antigens and S-protein; interferon activi...

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  6. 6

    Autoimmune encephalitis in psychiatric institutions: current perspectives by Bost C, Pascual O, Honnorat J

    Published 2016-10-01

    Chloe Bost,1–3 Olivier Pascual,2,3 Jérôme Honnorat1–3 1French Reference Center of Paraneoplastic Neurological Syndrome, Hospices Civils de Lyon, Hôpital Neurologique, Bron, France; 2Synatac Team, NeuroMyoGene Institut, INSERM U1...

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  7. 7

    Effect of low-energy extracorporeal shock wave on vascular regeneration after spinal cord injury and the recovery of motor function [Retraction] by Wang L, Jiang YQ, Jiang Z, Han LZ

    Published 2016-10-01

    Wang L, Jiang Y, Jiang Z, Han L. Effect of low-energy extracorporeal shock wave on vascular regeneration after spinal cord injury and the recovery of motor function. Neuropsychiatr Dis Treat. 2016 Aug 31;12:2189–2198. doi: 10.2147/NDT.S82864.This article was found to have plagiarized t...

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  8. 8

    ADVANCES AND PERSPECTIVES OF CLINICAL ABZYMOLOGY by S. V. Suchkov, Z. S. Alekberova, A. N. Hitrov, Z. S. Shogenov, O. V. Voskresenskaya, N. V. Gnuchev, A. G. Gabibov

    Published 2014-07-01

    Abstract. Natural catalytic autoantibodies (abzymes) posessing proteolytic (protoabzymes) and DNA-hydrolysing (DNA-abzymes) activities are detectable in clinical and experimental autoimmune disorders. Catalytic activity of abzymes is revealed in the patients with different forms of systemic (nonspec...

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  9. 9

    Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics by Yu. V. Yevsyutina, O. A. Storonova, A. S. Trukhmanov, V. T. Ivashkin

    Published 2014-12-01

    The aim of review. To present up-to-date data on etiology, pathogenesis, clinical presentation and diagnostics of cardiac achalasia.Key points. Cardiac achalasia represents primary esophageal motor disease with involvement of myenteric plexus. Basic symptoms of achalasia include dysphagia, regurgita...

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  10. 10

    DNA-abzymes in autoimmune diseases in clinic and experiment by T E Naumova, O M Durova, A G Gabibov, Z S Alelcberova, S V Suchkov

    Published 2003-02-01

    DNA-abzymes enzymes in autoimmune diseases in clinic and experiment T.E. Naumova, O.M. Durova, A.G. Gabibov, Z.S. Alekberova, S. V. Suchkov DNA-hydrolyzing autoantibodies (AAB) or DNA-abzymes can be found in autoimmune diseases in clinic and experiment. Technology of serum express screening for pres...

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  11. 11

    NEUROIMMUNOPATHOGENIC MECHANISMS OF EPILEPSY by Yо. N. Madjidova, G. S. Rakhimbaeva, R. B. Azizova

    Published 2016-05-01

    Abstract: the characteristics of some immunological Features were studied in 52 patients with epilepsy. The group of control included 10 healthy subjects of the comparable age.There were studied such immunological aspects in this group of patients as level of neurotropic autoantibodies to NF-200, GP...

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  12. 12

    ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER by A. I. Autenshlus, A. V. Sosnina, E. S. Mikhailiva, A. P. Lykov, Yu. V. Tumanov, E. D. Danilanko, V. S. Samukov, I. A. Kostanyan, D. V. Morozov, M. M. Cherenkova, L. .A. Thvan, N. A. Varaksin

    Published 2014-07-01

    Antibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of IgG4-antibodies to human leukemia differentiation factor (HLDF), as compared with healthy individuals, whereas, in patients with colorectal ca...

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  14. 14

    Content of autoantibodies in teenagers with chronic pathology of upper respiratory tract who live in an industrial center by L. B. Masnavieva, I. V. Tikhonova, I. V. Kudaeva

    Published 2013-04-01

    Conditions of environment can become causes of developments of different pathologic processes in people, living in ecologically unfavorable regions. The aim. of the work was to study contents of autoantibodies in blood serum of teenagers with chronic pathology of respiratory tract living in areas co...

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  15. 15

    AUTOIMMUNE ASPECTS OF COLLAGEN HOMEOSTASIS DISORDER IN UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA by A. V. Yagoda, N. N. Gladkikh

    Published 2014-07-01

    Abstract. The levels of autoantibodies to collagen type I, II, III, IV and V were studied in blood plasma of 130 patients (18-32 years old) with undifferentiated connective tissue dysplasia, using immunoenzyme analysis. A correlation was revealed between the levels of autoantibodies to various colla...

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  16. 16

    Interstitial lung diseases and autoimmunity by E. L. Nasonov, L. P. Ananyeva, A. S. Belevsky

    Published 2025-05-01

    Lung disease is one of the most common manifestations of systemic autoimmune rheumatic diseases (SARDs), involving all parts of the respiratory system in the pathological process. Interstitial lung diseases (ILD) are of great importance and often lead to the development of progressive pulmonary fibr...

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  17. 17

    EVALUATION OF IMMUNOLOGICAL SHIFTS IN ADULTS AFTER IMMUNIZATION AGAINST INFLUENZA WITH A SUBUNIT-BASED, ABSORBED MONOVALENT VACCINE STRAIN A/CALIFORNIA/7/2009/(H1N1... by M. P. Kostinov, O. A. Terkacheva, S. N. Girova, N. E. Jastrebova, A. P. Cherdantsev

    Published 2014-07-01

    Abstract.    Seventy    healthy    volunteers  were    immunized    with    influenza    subunit    vaccine    strain    A/California/7/2009  /  (H1N1),  in  order  to  test  possible  changes  in  auto-reactivity.  It  was  shown  that  the  vaccine  is  safe  and  immunogenic.  In  addition,  it ...

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  18. 18

    CHARACTERISTICS OF AUTOIMMUNE INFLAMMATION IN THE PATIENTS WITH LUNG TUBERCULOSIS by A. A. Starshinova, A. М. Malkova, Yu. S. Zinchenko, N. Yu. Basantsova, M. V. Pavlova, E. N. Belyaeva, S. V. Lapin, A. V. Masing, E. A. Surkova, P. K. Yablonsky

    Published 2019-12-01

    Tuberculosis is a granulomatous disease caused by Mycobacterium tuberculosis, being characterized by the development of caseous granulomas in various organs, mainly in lungs. M. tuberculosis is known to be a trigger for autoimmune inflammation, due to the possible mimicry of bacterial proteins as au...

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  19. 19

    TNF, SOLUBLE RECEPTORS AND AUTOANTIBODIES TO TNF OF PATIENTS WITH RHEUMATOID ARTHRITIS AND HEALTHY DONORS by E. A. Golikova, J. A. Lopatnikova, N. S. Shkaruba, A. E. Sizikov, S. V. Sennikov

    Published 2012-05-01

    The content of autoantibodies to TNF in the sera of patients with rheumatoid arthritis (RA) in conjunction with the definition of soluble receptors and TNF was investigated. A significant increase in the content of TNF and I and II types soluble receptors to TNF in sera of RA patients in the acute s...

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  20. 20

    DETECTION OF MODIFIED LIPOPROTEINS IN ATHEROSCLEROTIC LESIONS OF HUMAN AORTA by P. V. Pigarevsky, O. Yu. Archipova, A. D. Denisenko

    Published 2014-07-01

    Abstract. Specific autoantibodies against acetylated, maleylated and malonic dialdehyde-(MDA)-modified lipoproteins are detectable in human plasma. Immunization of rabbits with autologous, correspondingly modified low-density lipoproteins (LDLs) did induce autoantibodies against acetylated, maleylat...

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