Ngā hua rapu - "atopic dermatitis"

Background. According to the currently existing hypothesis, epicutaneous sensitization is one of the leading mechanisms in the development of food allergy.The aim of this review was to analyze immune mechanisms in epicutaneous sensitization and the role of skin barrier impairment.We performed a lite...

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BackgroundInterleukins IL-4, Il-5, IL-10, IL-13 and IL-33 play an important role in atopic dermatitis patients. The aim of our study is to address several knowledge gaps in the understanding of interleukin dynamics in atopic dermatitis patients and the effects of dupilumab treatment.MethodWe conduct...

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Kjell Erik Julius Håkansson,1,2 Inge Raadal Skov,3 Steven Arild Wuyts Andersen,4,5 Zarqa Ali,6 Anders Løkke,7,8 Rikke Ibsen,9 Ole Hilberg,7,8 Howraman Meteran,1 Claus R Johnsen,10 Vibeke Backer,4,5 Charlotte Suppli Ulrik1,5 1Department of Respiratory Medicine, Copenhagen University Hospital - Hvidov...

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The aim of this investigation is the comparative study of changes in the surface phenotype of lymphocyte in patients with different forms of atopic diseases and latent sensitization.Materials and methods. The study was conducted on peripheral blood lymphocytes from 22 latent sensitization patients,...

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Background. Atopic dermatitis is a common chronic inflammatory skin disease affecting 2.6 % of the global population (204.05 million people), of which 102.78 million are children. Atopic dermatitis has a complex multifactorial nature. According to current understanding, the development of the diseas...

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Galectin-9 (Gal-9) is a multifunctional immunomodulatory molecule involved in cell growth, differentiation, adhesion, communication, and death. Galectin-9 mediates its physiological functions through interactions with multiple membrane receptors, including T-cell immunoglobulin mucin-domain containi...

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The article is dedicated to the issues of external therapy of atopic dermatitis in children. Atopic dermatitis is a chronic allergic inflammatory skin disease; in most cases, it is the first manifestation of atopic march. Timely and adequate pathogenetic external therapy of this disease using topica...

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Background. Psoriasis is classified as a systemic immune-mediated inflammatory skin disease, with a frequency of 2-3%. Taking vitamins for psoriasis accelerates the healing processes, normalizes metabolism, relieves the symptoms of the disease, improves the condition of the skin, hair and nails.Obje...

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Aim: Whether house dust mite (HDM) sublingual immunotherapy (SLIT) is effective for the skin symptoms of adult atopic dermatitis (AD) is unclear.Methods: HDM SLIT was added to conventional AD treatment for 10 HDM-sensitized AD patients with rhinitis for 2 years.Results: Seven out of ten enrolled pat...

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This study demonstrates that naturally derived vitamins, estimated from whole foods in the diets of young Chinese adults from Singapore and Malaysia, are associated with atopic dermatitis (AD). Higher intake of vitamins E, K1, C, B2, and D was associated with lower odds of AD. The protective effect...

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The article is devoted to the relevant problem of pediatrics - treatment of acute respiratory infections in children. It examines the feasibility of a comprehensive treatment of colds in children with mandatory use of non-sedating antihistamines that increase the effectiveness of conventional treatm...

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Atopic dermatitis (AD) is a common chronic skin disease affecting both children and adults. Currently lacking a clinical cure, AD presents significant physical and emotional challenges for patients and their families, substantially impacting their quality of life. This underscores significant unmet...

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BackgroundOncostatin M (OSM) is a cytokine that mediates inflammatory processes and is overexpressed in skin lesions of atopic dermatitis (AD). By amplifying neural responses to chemicals such as histamine, OSM increases sensitivity to pruritus. However, the morphological effects of OSM on periphera...

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Background: Allergic diseases and influenza share similar genetic backgrounds and pathophysiological mechanisms. Observational studies have established a correlation between these 2 conditions; however, the precise direction of the causal relationship remains unclear. This Mendelian randomization (M...

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Recent decades see a steady increase in the number of patients suffering from food allergies worldwide. Children have a variety of clinical symptoms of food allergy. Some patients have local allergic reaction in the oral cavity, other — atopic dermatitis or gastrointestinal allergy, and sometimes th...

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The article is devoted to the relevant problem of pediatrics - treatment of acute respiratory infections in children. It examines the feasibility of a comprehensive treatment of colds in children with mandatory use of non-sedating antihistamines that increase the effectiveness of conventional treatm...

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<b>Background/Objectives:</b> The treatment of atopic dermatitis frequently involves using a topical corticosteroid and a moisturizer. While the sequential application of these products is a common dermatological practice, their influence on drug penetration remains poorly understood. Th...

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Atopic dermatitis (AtD) is multifactorial inflammatory skin disease, one of the aspects of its pathogenesis is epidermal barrier dysfunction. Early development of AtD is associated with filaggrin dysfunction. Filaggrin is a protein involved in aggregation of keratin filaments in the upper layers of...

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Functional activity of gdТ-cells in atopic dermatitis (AD) in dependence on the disease stage and concomitant pathology character was studied. We investigated 86 patients: 54 women and 32 men aged 17—50 years. AD patients revealed significant insufficiency of the cell immunity, the most marked of th...

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Atopic dermatitis (AD) is a heterogeneous disease characterized by unpredictable flares, potentially leading to impaired mental health. Adult patients with a dermatologist-verified AD diagnosis received after their 18th birthday were grouped according to patient-reported flare activity between 2018...

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