Kết quả tìm kiếm - "atopic dermatitis"

Atopic dermatitis (AD) is a genetically determined chronic inflammatory skin disease characterized by itching, relapsing course, age-related features of the lesion morphology and localization. The etiological factors contributing to the development of AD are: allergic reactions, inflammatory reactio...

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BackgroundAtopic dermatitis (AD) is a chronic skin condition marked by persistent itching and dryness. The role of cuproptosis, a novel form of programmed cell death, in AD is not yet understood.MethodsThe GSE107361 dataset was obtained from the Gene Expression Omnibus (GEO) database. Cuproptosis-re...

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BackgroundAtopic dermatitis (AD) is a prevalent chronic inflammatory skin condition influenced by immune dysfunction, genetics, and environmental factors, with emerging evidence highlighting the critical role of skin and gut microbiota in its pathogenesis. This article uniquely integrates a systemat...

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To study CD1a+ Langerhans cells and their extensions in epidermis and values of IL-4, IL-10, IL-17 and IFN-g in cell-free skin exudate there have been examined 40 patients of atopic dermatitis depending on phase pathological process. There have been found an increase in both CD1a+ dendritic extensio...

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Alopecia areata is a common inflammatory immune-mediated disorder in which autoimmune response is triggered against hair follicles, thus leading to non-scarring hair loss on the scalp, face and other parts of the skin. Despite numerous studies concerning this issue, today there is no consensus on th...

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Atopic dermatitis (AD) is a chronic recurrent inflammatory disease accompanied by severe itching. One of the leading mechanisms underlying the development of AD is an imbalance of the Th1/Th2 cells immune response, which leads to an increased production of inflammatory mediators, including IL-1 fami...

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Hidradenitis suppurativa (HS) and atopic dermatitis (AD) are both inflammatory dermatoses that can significantly impact patient quality of life, however, limited research exists regarding their association. The purpose of this comprehensive review is to compare the inflammatory pathogenesis of HS an...

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BackgroundAtopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by severe itching. Reducing mediators of skin inflammation and itching is crucial for the treatment of AD. Cannabis sativa L. contains many types of cannabinoids and flavonoids, which exhibit antioxidant and anti-inf...

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Background: Identification of predictive biomarkers is crucial for formulating preventive interventions and halting the progression of atopic march. Although controversial, the use of accessible markers to predict or detect early onset of atopic diseases is highly desirable. Therefore, this study ai...

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Background. Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases in children. It manifests during the first year of life in majority of cases. Early AD manifestation is a risk factor for the development of other atopic spectrum diseases in the future. Nowadays, the abi...

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Toll-like receptors (TLRs) are the most studied among all Pattern Recognition Receptors, the main function of which is to initiate innate immune response by recognizing pathogen-associated molecular patterns of various microorganisms on the skin surface. TLR-mediated recognition plays an important r...

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Atopic dermatitis is a common chronic dermatosis of multifactorial nature with prevalence of genetic component and complex pathogenesis. In the pathogenesis of atopic dermatitis, an important role is played by hereditary determinism, leading to a violation of the state of the skin barrier, defects o...

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Background. Atopic dermatitis (AD) is an allergodermathosis that is widespread in children and adult populations. Sensibilization to food allergens prevails in children of early age, and to airborne allergens in older age. Impairments of skin barrier lead to increase in Staphylococcus aureus coloniz...

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Background. Excessive colonization of the skin by various bacteria and fungi can be noted in patients with atopic dermatitis (AD), and the prevalence of secondary infection complications 30–48%. Several studies have shown that Staphylococcus aureus colonization is 60–100% in patients with AD compare...

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Atopic dermatitis — is a chronic disease, with immune mechanisms leading to high level of immunoglobulin Е and abnormal skin reactivity. The current review is presenting the experimental and clinical study results regarding to Т-regulatory cells participation in atopic dermatitis immune response....

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Metalloproteinases (MMP) play a significant role in the mechanisms of maintaining chronic inflammation and tissue remodeling. The study of concentration changes in these enzymes in the blood serum of children with allergopathology is of great practical and scientific interest.Objective: to study the...

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The goal of this study was to detect the risk of developing different atopic dermatitis (AD) phenotypes in children (isolated or combined with other comorbid atopic diseases (AtD)) depending on serum concentrations of cutaneous T-cell attracting chemokine (CTACK)/CCL27. The main group comprised 37...

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We report a case of dupilumab-induced alopecia areata and psoriasis successfully treated with a JAK inhibitor. A 33-year-old woman presented with recurrent erythema and itching for over 10 years. Dermatological examination showed dry skin on the trunk and limbs, with widespread erythemas and papules...

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Background. Currently, in the treatment of atopic dermatitis universally recognized phototherapy narrowband ultraviolet B (narrow-wave UVB therapy) with a maximum emission at a wavelength of 311 nm, the effectiveness of which has been confirmed by numerous studies. Phototherapy occupies the second l...

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Chronic spontaneous urticaria and atopic dermatitis (AD) are chronic skin disorders characterized by itch. Although mast cells play an integral role in the pathogenesis of chronic spontaneous urticaria, their role in AD is unclear, having a contributory role in a disease largely driven by T helper 2...

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