खोज परिणाम - "atopic dermatitis"

The article describes the main characteristics of local glucocorticosteroids (GCS) which are the «gold standard» for external therapy of atopic dermatitis allowing to achieve control over  the disease quickly and effectively. Methylprednisolone aceponate 0.1%  — non-fluorinated local GCS, the drug w...

पूर्ण विवरण

ObjectiveThe dissemination of Molluscum contagiosum (MC), a prevalent pediatric cutaneous viral infection, is enhanced upon atopic dermatitis (AD) or compromised epidermal barrier function. However, the potential influence of AD on the course of MC remains controversial. This study aimed to evaluate...

पूर्ण विवरण

Atopic dermatitis (AD) is a chronic inflammatory skin disease. Its crucial component of pathogenesis is malfunction of the epidermal barrier. Filaggrin protein and associated mutations in the filaggrin gene play one of the key roles in this problem. Nowadays new topical products (emollients) has bee...

पूर्ण विवरण

Atopic dermatitis (AD) is a chronic inflammatory skin disease with high risk of skin and systemic infections. Preventive AD therapy is based on skin barrier improvement and anti-inflammatory treatment, whereas, severe skin and systemic infections require systemic therapy. This review describes patho...

पूर्ण विवरण

Background The decision to initiate advanced systemics in patients with atopic dermatitis (AD) is complex.Objectives To explore disease burden and clinical characteristics of patients with moderate-to-severe AD and identify characteristics associated with initiating new systemics.Methods Data from p...

पूर्ण विवरण

Atopic dermatitis (AD) is the disease with chronic inflammation, epidermal barrier dysfunction and microbial dysbiosis. AD is widespread, including pediatric population. The article discusses the disease’s pathogenesis: skin barrier deficiency, immunological causes of chronic inflammation, character...

पूर्ण विवरण

BackgroundChildren with atopic dermatitis (AD) have a higher likelihood of developing asthma, the so-called atopic march. Previous studies have suggested that probiotics can modulate development of the immune system and atopic disorders. However, the exact mechanisms and whether the route of adminis...

पूर्ण विवरण

Atopic dermatitis is a chronic allergic inflammation of skin. Topical corticosteroids, calcineurin inhibitors, skin emollients, antimicrobial preparations (in complicated cases), allergen and irritant elimination are used for topical treatment of atopic dermatitis. State of the art strategy for atop...

पूर्ण विवरण

The problem of the peculiarities of the course of allergic diseases during pregnancy, as well as rational and safe approaches to their treatment, is in the focus of close attention of specialists. The article presents the clinical and pathogenetic characteristics of atopic dermatitis in pregnant wom...

पूर्ण विवरण

Recently, the relationship between autoimmune diseases and atopy is one of the important areas of scientific studies. There is evidence of a relationship between atopy and psoriasis (PS). Thus, the study of sIgE concentration to 44 causally significant allergens was performed using PROTIA™ Allergy-Q...

पूर्ण विवरण

Healthy newborn skin care is challenging task. The basic principles of care should be taught to both medical staff and parents. This care is more crucial in children with atopic dermatitis who have abnormal skin acidity due to multifactorial exposure. Significant pH reduction leads to aggravation of...

पूर्ण विवरण

(1) Background: The IL-36 cytokines have been identified as key contributors to pustular psoriasis, and their inhibitor is already in clinical use. However, few studies have explored them in atopic dermatitis. (2) Methods: The role of IL-36α was investigated in various atopic dermatitis models using...

पूर्ण विवरण

Purpose of the study Head, neck (HN), and face involvement in atopic dermatitis (AD) poses a major psychological burden and can be challenging to effectively treat. New appearance of HN dermatitis has been reported with biologics used to treat AD. Lebrikizumab (LEBRI), a monoclonal targeting IL-13,...

पूर्ण विवरण

Bronchial asthma (BA) and allergic diseases such as allergic rhinitis (AR) and atopic dermatitis (AtD) are the most common chronic diseases, the prevalence of which is growing among the child population with the urbanization and industrialization of society. These diseases place a heavy burden on pa...

पूर्ण विवरण

<b>Background:</b> This study pioneers the exploration of the role of cuproptosis (a novel form of regulated cell death) in the pathogenesis of atopic dermatitis (AD). <b>Methods:</b> We integrated two datasets (GSE157194 and GSE193309) from the GEO database and employed weig...

पूर्ण विवरण

IntroductionPrevious meta-analyses of multiple studies have suggested that probiotics supplementation plays a role in reducing the risk of atopic dermatitis (AD). However, the conclusions of these studies remain controversial.MethodsWe conducted an umbrella review of meta-analyses to comprehensively...

पूर्ण विवरण

The article describes the results of therapy with autologous activated. T-lymphocytes in patients with atopic dermatitis. Has been shown high clinical efficacy and safety of this therapy in the treatment of patients with both allergic and nonallergic form of the disease. In the allergic form observe...

पूर्ण विवरण

<b>Background/Objectives</b>: Allergens can trigger severe immune responses in hypersensitive individuals, with mast cells releasing inflammatory mediators via IgE-FcɛRI signaling. Spleen tyrosine kinase (Syk) is a key regulator in this pathway, making it a promising therapeutic target....

पूर्ण विवरण

Epigenetic age acceleration has previously been observed in inflammatory skin disease; however, less is known regarding recently described age-related gene expression patterns (“transcriptional clocks”). We investigated the role of transcriptional clocks in patients with hidradenitis suppurativa (n...

पूर्ण विवरण

Background. Alopecia areata is an autoimmune disease characterized by hair loss that develops with the involvement of CD8+ T-cells of the immune system and cytokines produced by T-helper 2 cells (Th2). Efficacy of alopecia areata management is limited. The one potentially effective variant for treat...

पूर्ण विवरण