Torthaí cuardaigh - "atopic dermatitis"

Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide, significantly impairing patients’ quality of life. It is characterized by recurrent eczematous lesions, intense pruritus, and disruption of the epidermal barrier. The pathogenesis of AD is multifactorial a...

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The skin surface is colonised by a rich microbiome, and intricate interactions between this microenvironment and microbial communities are critical for maintaining skin homeostasis. Atopic dermatitis (AD), a chronic inflammatory skin disease characterised by skin barrier dysfunction and aberrant imm...

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<b>Background/Objectives</b>: Atopic dermatitis (AD) is a chronic inflammatory skin condition with rising global prevalence. Increasing maternal antibiotic use during pregnancy has raised concerns about its potential link to childhood allergic diseases, including AD. However, existing me...

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Bacterial, allergic, parasitic and fungal skin lesions are much more common among children than among adult patients. The aim of this study was to analyze data on the prevalence and incidence of diseases of skin and subcutaneous tissue with allergic and non-allergic origin among children of Ukraine...

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Health disparities in allergic and immunologic conditions are shaped by unequal exposure to social determinants of health (SDoH), including education, healthcare quality, neighborhood and built environment, social context, and economic stability. This review summarizes recent literature on dispariti...

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Various conclusive evidence on the role of vitamin D in the pathogenesis of atopic dermatitis (AD) has been obtained in recent decades. Many studies have shown that patients with AD have low concentration of 25(OH)D in blood associated with high concentration of allergen specific IgE (according to s...

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Currently, there are only scarce data on dynamics of biologically active substances in the lesions associated with atopic dermatitis. Persistence of microorganisms in atopic dermatitis is high on the skin surface. However, pathophysiological significance of ENA-78/CXCL5 for development of atopic der...

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Atopic dermatitis (AD) is a widely recognized chronic inflammatory skin disease influenced by dietary habits, stress, genetic factors, and environmental factors. This study aimed to explore the impact of stress on AD exacerbation, as well as the associated changes in the gut microbiota. We utilized...

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Type I allergies are triggered by immunoglobulin E (IgE)-mediated hypersensitivity reactions upon allergen exposure. Dogs are diagnosed with allergic dermatitis based on history, clinical signs, and allergen-specific IgE detection. Using the multiple allergen simultaneous test (MAST)–immunoblot assa...

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Chicken egg is among the most important sources of allergens. Sensitization to them is most often manifests as food allergy (FA), and/or atopic dermatitis (AD). Immunogenic substances of a chicken egg are present in both white egg and yolk.The purpose of our work was to compare frequency and intensi...

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Introduction. The increasing prevalence of allergic diseases, the variety of clinical forms, the severity of manifestations and a significant violation of the quality of life of patients determine the importance of the allergy problem and the search for its solutions. The purpose of the review is to...

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Chiharu Watanabe Chiharu Dermatology, Tokyo, JapanCorrespondence: Chiharu Watanabe, Chiharu Dermatology, 2F Barbizon 86, 5-3-13, Hiroo, Shibuya-ku, Tokyo, 150-0012, Japan, Tel +81334471177, Fax +81334471178, Email chiharu-hifukaclinic@iris.ocn.ne.jpPurpose: Skin health is deeply linked with the bala...

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Background. Malformations in epidermal barrier in children with atopic dermatitis (AD) can cause transcutaneous sensitization with further development of allergic diseases that can worsen the AD course and significantly reduces patients’ quality of life.Objective. The aim of the study was to determi...

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The results of previous studies suggest the involvement of herpes viruses in the development of atopic dermatitis and psoriasis, but there is no convincing evidence. Aim of the study was to evaluate the role of active herpesvirus infection in exacerbation of atopic dermatitis and psoriasis. Material...

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Mesenchymal stem cell (MSC) therapy holds promise for treating immune-mediated inflammatory skin diseases (IMIDs), particularly when conventional therapies are ineffective. Encouraged by their immunomodulatory capabilities and potential for disease modification, different clinical trials are investi...

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ABSTRACT Gaining a deeper understanding of the variation in skin microbiota across habitats and layers provides critical insights into the complex host-microbial interactions that drive inflammatory skin diseases. Our study investigated dermal versus epidermal microbiota in lesional and non-lesional...

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Background. The association between the vitamin D provision for children and the atopic dermatitis (AD) development and severity is not clearly determined.Objective. The aim of the study was to compare 25(OH)D serum concentration in children with AD and in healthy peers with association analysis of...

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Immune checkpoint inhibitors (ICIs) have become mainstay therapy in the treatment of certain cancers. However, they are frequently associated with adverse effects in nontumor tissues. Cutaneous immune-related adverse events are the most prevalent toxicities, yet their underlying mechanisms remain po...

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<b>Background:</b> Atopic dermatitis (AD), allergic rhinitis (AR), and chronic rhinosinusitis with nasal polyps (CRSwNP) represent interconnected conditions within the spectrum of type 2 inflammatory diseases. While these conditions share common genetic and epigenetic pathways, the preci...

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Background: Allergic-related skin diseases, including atopic dermatitis (AD), urticaria, and contact dermatitis (CD), are significant global public health challenges. Currently, there is a lack of systematic analysis of allergic-related skin diseases globally. Methods: This study aimed to quantify t...

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