Search Results - "anaphylaxis"

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  1. 1

    Differences between multi-triggered and single-triggered food anaphylaxis in children: a real life study by Şule Büyük Yaytokgil, İlknur Külhaş Çelik, Zeynep Şengül Emeksiz, Betül Karaatmaca, Tayfur Giniş, Selma Alim Aydın, Müge Toyran, Emine Dibek Mısırlıoğlu, Ersoy Civelek

    Published 2025-07-01

    Background. Food-induced anaphylaxis (FIA) is a severe form of food allergy, and literature data about multi-triggered FIA is scarce. This study aimed to evaluate the differences between multi-triggered and single-triggered food anaphylaxis in children. Methods. The study included pediatric patie...

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  2. 2

    Tryptase in children in the practice of an allergist by D. Sh. Macharadze

    Published 2023-03-01

    The normal serum tryptase level is 0–11.4 ng/ml. Hypertryptasemia occurs with anaphylaxis, systemic mastocytosis, and cutaneous mastocytosis in children. Recently, mast cell activation syndromes are increasingly being diagnosed. The article discusses the main reasons for the increase in the concentr...

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  3. 3

    A rare case report of catecholamine-induced takotsubo in a patient with anaphylaxis shock due to amoxicillin–clavulanate by Thang Quoc Le, Thanh Huu Nguyen, Anh Duc Vu, Hai Dang Pham

    Published 2025-04-01

    Takotsubo syndrome (TTS), also known as stress cardiomyopathy, is a life-threatening condition characterized by transient left ventricular dysfunction with nonischemic abnormalities. This syndrome in scenarios of anaphylactic shock is quite rare, with only a few cases reported. Early diagnosis and t...

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  4. 4

    CLINICAL CASE OF FOOD ANAPHYLAXIS IN A CHILD: DETECTION OF THE MAIN ALLERGENIC TRIGGERS BY MEANS OF MOLECULAR COMPONENT ANALYSIS by Zh. M. Zlobina, M. A. Mokronosova

    Published 2014-11-01

    Anaphylaxis is an acute potentially life-threatening syndrome; in children, it is usually triggered by food allergy. Virtually any food may serve as a provocative factor for an anaphylactic reaction, which is why timely detection of clinically significant allergens is important for prognosis and pre...

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  5. 5

    Evaluation of the awareness of pediatric residents of anaphylaxis diagnosis through clinical scenarios by Tülay Tuğçe Kutsal Gültekin, M.D., Ayşe Gökçe Kutsal, M.D., Gökhan Yörüsün, M.D., Ahmet Selmanoğlu, M.D., Kaan Çelebier, M.D., Zeynep Şengül Emeksiz, Emine Dibek Mısırlıoğlu

    Published 2025-07-01

    Introduction: Anaphylaxis is an acute onset, life-threatening systemic hypersensitivity reaction requiring urgent medical intervention. Early recognition and appropriate treatment of anaphylaxis are crucial for patient survival. This study aims to assess the awareness of pediatric residents regardin...

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  6. 6

    Anaphylaxis: the main triggers and clinical picture by I. I. Balabolkin, D. Sh. Macharadze, A. Yu. Konischeva

    Published 2021-06-01

    Types of anaphylaxis - severe systemic reaction of hypersensitivity characterized by rapid beginning and life-threatening problems of respiratory tracts and blood circulation – were considered. The most wide-spread triggers of this condition and clinical manifestations of anaphylaxis were presented....

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  7. 7

    Blood Leukocyte Ratios: Equivocal Parameters for Allergic Diseases by Alper Ekinci, Seda Altıner

    Published 2025-03-01

    Objectives: Leukocytes play crucial roles in allergic and immunologic diseases. We compared neutrophil-lymphocyte ratio (NLR), basophil-lymphocyte ratio (BLR), eosinophil-neutrophil ratio (ENR), and eosinophil-lymphocyte ratio (ELR) in 100 drug-induced urticaria-angioedema, 100 drug/venom-triggered...

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  8. 8

    Biomarkers of anaphylaxis by N. V. Esakova, A. A. Lebedenko, A. N. Pampura

    Published 2022-09-01

    Anaphylaxis is a severe, life-threatening, systemic hypersensitivity reaction that develops rapidly and can lead to death. The diagnosis of anaphylaxis continues to be primarily clinical. Therefore, a large number of studies are initiated annually aimed at a deeper study of the mechanisms of the dev...

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  9. 9

    Intensive Care for Anaphylaxis in Children: Current Trends by Yu. V. Bykov, A. N. Obedin, V. V. Fischer, E. V. Volkov, O. V. Zinchenko

    Published 2024-10-01

    Anaphylaxis is an acute allergic reaction with rapid clinical development and risk of death. This article provides an analysis of literary sources devoted to intensive care of anaphylaxis in childhood. It was revealed that the prevalence of anaphylaxis is increasing, in children and adolescents as w...

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  10. 10

    First-in-class intranasal epinephrine spray for anaphylaxis: Dose finding clinical study by Tair Lapidot, PhD, Yuval Tal, MD, PhD, Dalia Megiddo, MD, Galia Temtsin Krayz, PhD, Carolina Abrutzky, BSc, Simcha Blotnick, PhD, Oded Shamriz, MD, Alon Hershko, MD, PhD, Yoseph Caraco, MD

    Published 2025-08-01

    Background: Anaphylaxis is a life-threatening clinical presentation of acute systemic allergic reactions. Timely administration of epinephrine, usually by intramuscular autoinjector, is a robust life-saving treatment. Despite the critical necessity, there are multiple deterrents to patients’ proper...

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  11. 11

    A clinical case of anaphylactic shock development after anesthesia induction by K. N. Khrapov, A. A. Khryapa, I. V. Vartanova, S. S. Sedov, Yu. S. Okhapina, E. G. Gavrilova

    Published 2021-05-01

    The article describes a clinical case when a patient who was supposed to have a planned surgery on the spine developed anaphylactic shock. After 10 minutes of anesthesia introduction, the patient developed severe hypotension (resistant to the administration of adrenomimetics) and tachycardia; a decr...

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  12. 12

    Pediatric anaphylaxis in the emergency department: Performances of dynamic tryptase measurement by Constance Gonzalez, MD, Meng Sun, MSc, Aurélie Morand, MD, PhD, Philippe Minodier, MD, Marc Leone, MD, PhD, Jean-Christophe Dubus, MD, PhD, Joana Vitte, MD, PhD, Moïse Michel, PharmD, PhD

    Published 2025-08-01

    Background: Dynamic measurement of serum acute (sAT) and baseline (sBT) tryptase confirms mast cell degranulation during systemic hypersensitivity reactions, provided timing and interpretation are appropriate. The current consensus formula requires sAT greater than a personalized cutoff value [sAT &...

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  13. 13

    Case report of vaccine-induced anaphylactic reaction reclassified after vaccine challenge by Maria Aman, MBBS, Chirine A. Abou Turk, MD, John C. Carlson, MD, PhD

    Published 2025-08-01

    At age 4 months, an infant had skin changes and cessation of breathing responsive to epinephrine after vaccine administration. The atypical breathing recurred during vaccine challenge but was consistent with breath-holding spell rather than anaphylaxis. Vaccine challenges can be performed in appropr...

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  14. 14

    Features of the clinical course and treatment of anaphylaxis in children in the Ryazan region according to survey data by E. V. Stezhkina, N. A. Belykh, A. I. Agapova, D. I. Suleymanova, A. N. Belyaeva

    Published 2024-01-01

    Anaphylaxis is a life-threatening systemic hypersensitivity reaction with the rapid development of critical changes in hemodynamics and /or disorders of the respiratory system, which can lead to death. Despite the trend towards the spread of anaphylaxis among children, there are difficulties in moni...

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  15. 15

    Sensitization to food allergies in the context of atopic comorbidity by P. Yu. Isaev, O. I. Urazova, V. V. Klimov, M. I. Musina, D. S. Zagreshenko, A. A. Denisov, Ya. V. Kukharev, A. N. Shkatova, A. V. Klimov

    Published 2025-07-01

    The lecture considers a place of food allergy in the profile of allergic and, in particular, atopic diseases and its features, distinguishing this pathology from all other allergies. Three classes of food allergens are characterized, and sensitization to them involving cells and regulatory molecules...

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  16. 16

    EVALUATION OF ANAPHYLAXIS KNOWLEDGE LEVELS IN 4TH AND 5TH YEAR STUDENTS OF FACULTY OF DENTISTRY by Salih Düzgün, Mehmet Doğan, Emre Bulbul

    Published 2025-07-01

    Objective: Anaphylaxis is a rapidly developing and life-threatening phenomenon. Rare cases of anaphylaxis may occur during dental practice and may cause loss of life in patients. This study aimed to evaluate the level of anaphylaxis knowledge in 4th and 5th-year dental students.Methods: This descrip...

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  17. 17

    Modern Recommendations for Treating Anaphylactic Shock in Children by R. F. Tepaev, L. R. Selimzyanova, L. S. Namazova-Baranova, E. A. Vishnyova

    Published 2015-11-01

    Anaphylaxis is an immediate hypersensitivity reaction. It is characterized by the rapid development of life-threatening conditions caused by circulatory and respiratory disorders, in some cases with lesions of the skin and mucous membranes, and is associated with serious complications, including dea...

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  18. 18

    Cholinergic urticaria in pediatricians’ practice by R. F. Khakimova, O. V. Skorokhodkina, A. R. Klucharova

    Published 2023-03-01

    Chronic urticaria (CholU) is a relevant problem in pediatrics due to its high frequency among other physical forms of chronic urticarial especially in adolescence. We present current data of pathogenesis, diagnostic criterias and principles of therapy of CholU using up-to-date clinical guidelines. A...

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  19. 19

    <i>Salvia miltiorrhiza</i> Root Extract as a Potential Therapeutic Agent for IgE/Ag-Induced Allergic Reactions and Atopic Dermatitis via the Syk/MAPK Pathway by Min-ah Kim, Jin-Ho Lee, Keunjung Woo, Eunwoo Jeong, Tack-Joong Kim

    Published 2025-06-01

    <b>Background/Objectives</b>: Allergens can trigger severe immune responses in hypersensitive individuals, with mast cells releasing inflammatory mediators via IgE-FcɛRI signaling. Spleen tyrosine kinase (Syk) is a key regulator in this pathway, making it a promising therapeutic target....

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  20. 20

    Food anaphylaxis in children by T. S. Lepeshkova, E. K. Beltyukov, S. A. Tsarkova

    Published 2023-03-01

    Food anaphylaxis is a severe life-threatening reaction  to food.  In recent years, there has been an increase  in the number  of such reactions.  The ability to recognize  the symptoms of food  anaphylaxis surrounding a sick person by people is the key to a saved  life.  This article on the basis of...

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