Search Results - "alterity"

The modernist literary experiment is widely credited with opening up different conceptual mechanisms whereby the other might be welcomed into the world without the risk of being appropriated by the same. In this line of thought, modernist literature can be reimagined as presenting an ethical project...

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The denotative and theoretical indeterminacy make the sense of touch an ambiguous concept to work with. While materiality and relationality, traditionally assigned in philosophical discourses and acknowledged through scientific research, are considered as the inherent dimensions of touch, the paper...

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The question is whether we can even speak about alterity in our current world, whether the meeting of the other is possible at all, and if it is, whether it should be discussed in an ontical-ontological, an ethical (Lévinas), or a social (Baudrillard) framework. In the ecstasy of communication (Bau...

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The Role of Alterity and of the Digital Media in Outlining of the Postmodern Individual’s Identity. The postmodern individual forms his identity, his self-image and self-perception not only through self-reflection or through reference to his own convictions, his own system of values and principles....

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Following text deals with the problems of relationships between the French society and “the other”. The emphasis is put on the context and discourses of political elites during the 19th and 20th century that influenced the creations and the transformations of structured representations not only of “...

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An investigation was made into the clinical features of cardiac-vascular system of 200 patients with antiphospholipid syndrome (APS): 61 patients had PAPS (primary APS), 139 patients had SAPS (secondary APS), associated with systemic lupus erythematosus (SLE) (115 cases) or Sharp syndrome (24 cases)...

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Background and Aims: Congenital plasminogen deficiency type 1 (PLGD1) is an ultrarare disease characterized by the development of fibrin-rich pseudomembranes on mucosal surfaces of several organs and systems, mainly involving the conjunctiva. In affected females, ligneous lesions may occur on the v...

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Das Alter wird in Gerontologie und Sozialwissenschaften, aber auch in der Kulturindustrie und Werbewirtschaft entdeckt. Auch die Religionspädagogik muss sich damit beschäftigen. Denn dort liegen große Herausforderungen gerade für ein auf Bildung und Mündigkeit abzielendes religiöses Lernen. Der Tex...

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Background and Aims: Pre-eclampsia (PE) is the leading cause of adverse cardiovascular (CV) outcomes during and after pregnancy. Thromboxane (TX)-dependent platelet activation plays a key role in PE pathogenesis. Urinary 11-dehydro-TXB2, a major TX metabolite (TXM), is reduced by at least 75% by lo...

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Background and Aim: Platelets play a key role in hemostasis and immune response during infection. In sepsis, platelets interact with endothelial cells and leukocytes, contributing to inflammation and microvascular thrombosis. Thrombocytopenia is a known marker of poor prognosis, whereas platelet dy...

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Background and Aims: Reticulated platelets (RePLTs) are bigger and more reactive than mature platelets (PLTs), with an increased content of ribonucleic acid (RNA) and directly released by megakaryocytes. In liver cirrhosis the increased platelet turnover implies the release of these “emergency plat...

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Background: Central nervous system (CNS) involvement is well-documented in acute immune-mediated thrombotic thrombocytopenic purpura (iTTP). Glial fibrillary acidic protein (GFAP), a marker of astrocytic injury, and neurofilament light chain (NfL), an indicator of axonal degeneration, are emerging...

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Background and Aims: Heparin-Induced Thrombocytopenia (HIT) is a clinical syndrome that may cause thrombotic complications in patients receiving heparin therapy. The 4T score assesses pre-test probability: if intermediate or high, an immunological test is required to detect anti-heparin/PF4 antibod...

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Background and Aims: Recognizing patients with inherited platelet disorders (IPD) still represents a challenge, and a multidisciplinary approach is routinely required. We have established a method for phenotyping platelets on the peripheral blood smear using immunofluorescence- and light microscopy...

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Background: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a life-threatening microangiopathy often characterized by acute neurological involvement during the acute phase followed by neurological complications during remission, due to microvascular damage. Cerebral small vessel disea...

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Background and Aims: The bicuspid aortic valve (BAV) is the most common congenital cardiopathy affecting 0.5 to 2.0% of the general population. This condition can cause secondary complications such as valvular aortic stenosis, calcification, aortic insufficiency and thoracic aortic aneurysm. Beyond...

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Background and Aims: Glanzmann thrombasthenia (GT) is an autosomal recessive platelet disorder with reduced αIIbβ3 expression or function and normal platelet count, caused by a reduced expression or dysfunction of integrins αIIb or β3 encoded by the genes ITGA2B and ITGB3 respectively. Dominant gai...

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Background and Aims: Variability in platelet cyclooxygenase-1 (COX-1) turnover affects individual responses to aspirin (ASA). Due to ASA’s short half-life, increased platelet (PLT) production can limit its antiplatelet effect over 24 hours. We previously showed that poor ASA responders have enhance...

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Background: KRAS mutant malignant cells can lead to overexpression of tissue factor (TF), a main contributor to cancer associated thrombosis (CAT). The relationship between KRAS mutations and the risk of recurrent venous thromboembolism (VTE) in gastrointestinal cancer patients with established CAT...

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