Rezultaty - "University of Ottawa"

Abstract Mild traumatic brain injury (mTBI) is neurological impairment induced by biomechanical forces without structural brain damage, currently without an objective diagnostic tool. Downstream injury stems from oxidative damage leading to the production of neurotoxic aldehydes. A collagen-based 3D...

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Summary: Background: Guidelines recommend that adults with peripheral artery disease (PAD) take antiplatelets, statins, and antihypertensives. However, it is unclear how frequently clinicians do not prescribe these medications (ie, underprescription), how often patients fail to fill/refill their pr...

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IntroductionOvarian cancer is the most lethal gynecological malignancy. Deepening our knowledge of the interactions within the tumor microenvironment (TME) is important for discovering new targeted treatment strategies. Transglutaminase 2 (TG2) is a protein implicated in many biological and pathophy...

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As phase-based sensors, surface plasmon interferometers offer higher sensitivity than resonant or attenuation-based plasmonic sensors. In this paper we realize surface plasmon interferometric sensors based on a multimode nanoslit used as a combiner. The phase difference in the surface plasmon waves,...

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IntroductionCouple relationships are important for health. Relationship distress is associated with increased incident and prognostic cardiovascular risk, while positive support is linked to heart-healthy behaviors and improved outcomes. This paper describes the study rationale, objectives, design,...

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IntroductionOvarian cancer (OVCA) has a five-year survival rate of approximately 45%, with little improvement over recent decades. Although anti-PD-L1 therapies have shown substantial efficacy in other solid tumors, their effectiveness in OVCA has been limited. These treatments target only membranou...

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Introduction: Prior to transcutaneous aortic valve replacement (TAVR), a CT is performed (TAVR-CT). With modification, the CT exam can measure myocardial extracellular volume (ECV). A small increase in ECV occurs in severe aortic stenosis. A large increase in ECV occurs when transthyretin cardiac am...

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Multiple sclerosis (MS) is a progressive inflammatory disease of the central nervous system (CNS) marked by myelin loss, which impairs nerve function. Current therapies fail to halt disease progression or prevent myelin and axonal degeneration. In this study, we explored the impact of miR-145 loss i...

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Vaccine hesitancy, particularly among racialized communities, persists due to misinformation, medical mistrust, and systemic barriers. This study examines racial disparities and key determinants related to perceptions of COVID-19 vaccine effectiveness in Canadian parents from Arab, Asian, Black, Ind...

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Background: This study aimed to develop head circumference (HC) growth charts specific to infants and young children diagnosed with benign enlargement of the subarachnoid spaces. By modeling HC trajectories, we sought to establish normative curves that distinguish benign macrocephaly from pathologic...

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Monitoring the state of the optical network is a key enabler for programmability of network functions, protocols and efficient use of the spectrum. A particular challenge is to provide the SDN-EON controller with a panoramic view of the complete state of the optical spectrum. This paper describes an...

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Cumulative experiences of racism lead to stress and trauma. Racial trauma is associated with compromised functioning across psychological, social, and physical health domains. This is further complicated by any comorbidity with other mental health conditions. Many clinicians are not trained in ident...

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Presents corrections to the above named paper.

IntroductionVentilation-perfusion (V/Q) nuclear scintigraphy remains a vital diagnostic tool for assessing pulmonary embolism (PE) and other lung conditions. Interpretation of these images requires specific expertise which may benefit from recent advances in artificial intelligence (AI) to improve d...

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Background: Prosthetic shoulder infection is the most common reason for revision arthroplasty within 2 years of the index procedure. Due to the preponderance of indolent and slow-growing infection in shoulder arthroplasty, establishing a diagnosis of infection prior to revision shoulder arthroplasty...

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