Hakutulokset - "Tohoku University"

<b>Background</b>: An acute angle-closure attack (AAC) is an ocular emergency that results from a rapid increase in intraocular pressure (IOP). Sustained IOP elevation induces severe degeneration of retinal ganglion cells (RGCs) without treatment. Overactivated microglia, key participant...

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Despite the advances in surface-display systems for directed evolution, variants with high affinity are not always enriched due to undesirable biases that increase target-unrelated variants during biopanning. Here, our goal was to design a library containing improved variants from the information of...

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Cadherins are key cell adhesion molecules that engage in extracellular homophilic binding. CDH15/M‐cadherin is localized to the apical surface of muscle satellite cells (SCs), which play a critical role in tissue regeneration after injury. Although CDH15 is considered a marker of SCs, there is no an...

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Optimizing powder bed quality is crucial for enhancing the quality of objects manufactured through the powder bed fusion additive manufacturing (PBF-AM) process. In this study, we propose an optimal particle size distribution (PSD) to improve powder bed density and homogeneity during the recoating p...

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A novel configuration of mutually injection-locked directly modulated lasers (DMLs) for generating in-phase quadrature (IQ) optical signals is proposed and numerically investigated by using rate equations. Two DMLs coupled with a high-Q ring resonator (Q &#x003D; 2.2 &#x00D7; 10<sup>5&...

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This study aimed to monitor the operating state of an induction motor, a type of electromagnetic motor, using a highly sensitive magnetic sensor, which could be applied for anomaly detection in the future. Monitoring the health of electromagnetic motors is very important to minimize losses due to fa...

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We developed a photothermal deflection spectroscopy (PTDS) system for the noninvasive analysis of biological tissue. This system detects heat induced by irradiation with pulse-modulated mid-infrared light as the deflection of a probe laser. The probe light is incident on the sensing element horizont...

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We propose and demonstrate a measurement technique of the intrinsic modulation responses of semiconductor lasers with high sensitivity in a wide modulation frequency range. The technique is based on the two-tone optical modulation and lock-in detection of an optical spectrum having modulation sideba...

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ABSTRACT Hypopituitarism has been reported in patients receiving continuous infusions of prostaglandin I2 (PGI2) analogues for pulmonary hypertension (PH). However, these patients' clinical characteristics, treatment, and prognoses remain unclear. This retrospective multicentre study included 2...

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Introduction and aims: Differentiating restorative materials from enamel during dental examinations is challenging because of their similar appearances. Even with ultrasound microscopy, the acoustic properties of restorative materials remain unassessed. This study investigated the potential of ultra...

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Accurate characterization and evaluation of hazardous rockmass sources prove essential for rockfall risk mitigation. Structural properties of rock masses play a decisive role in evaluating these risks. This study presents an integrated approach that combines Terrestrial Laser Scanning (TLS) and Unma...

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A strategy is proposed to enhance the stability and reusability of the ReOx‐Pd/CeO2 catalyst for the consecutive deoxydehydration and hydrogenation (DODH + HG) of biomass‐derived vicinal diols. A remarkable result involving a simultaneous enhancement of activity, stability, and regeneration ability...

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This study examines the tensile behavior of lean duplex stainless steel SUS821L1, a low-nickel alloy with potential for structural applications. Quasi-static and dynamic tensile tests are conducted over a temperature range of 233–293 K. Dynamic tests use a vertical split-Hopkinson tensile bar (SHTB)...

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Recent observations indicate that stripped-envelope core-collapse supernovae are often surrounded by dense circumstellar material (CSM). Motivated by this, we develop an analytic model to systematically study the dynamics of long gamma-ray burst (LGRB) jet propagation in various CSM environments. We...

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This paper deals with two thermoelastic problems of an infinite slab with or without a cylindrical hole. The thermal stress distribution which arises in a slab if a circular region of the plane boundary (Case A), or a cylindrical boundary (Case B) undergoes a sudden temperature change, is analysed...

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We apply a machine learning (ML) approach to predict the properties of glass optical diffusers fabricated by ablation-assisted nanosecond laser machining. This ‘indirect’ laser machining utilizes the interaction between the glass substrate and ablated fragments which are produced by nanosecond laser...

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Abstract: von Willebrand disease (VWD) is a common inherited bleeding disorder. The aim of this study was to determine the predicted disease states associated with various pathogenic von Willebrand factor (VWF) variants and their phenotypes using the largest Japanese whole-genome database. Of the 58...

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Recent high- z quasar observations strongly indicate that super-Eddington accretion is a crucial phase to describe the presence of supermassive black holes (SMBHs) with M _BH  ≳ 10 ^9 M _⊙ at z  ≳ 7. Motivated by theoretical predictions that the super-Eddington phase efficiently produces outflows an...

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Summary: Fluorescence-labeled tiny DNA origami blocks (FTOBs) enable observation of kinesin motility and their cooperation with minimal blinking and photobleaching. Here, we present a protocol for assembling FTOBs to observe kinesin cooperation. We describe steps for linking FTOBs and kinesins via a...

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Abstract While slow slip events (SSEs) are recognized as a ubiquitous phenomenon in subduction zones, accurately tracking the spatiotemporal distribution of shallow SSEs remains challenging. Here, we investigate the potential occurrence of shallow SSEs in the southern Ryukyu forearc at the western b...

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