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361
Big team science reveals promises and limitations of machine learning efforts to model physiological markers of affective experience
Έκδοση 2025-06-01Λήψη πλήρους κειμένουResearchers are increasingly using machine learning to study physiological markers of emotion. We evaluated the promises and limitations of this approach via a big team science competition. Twelve teams competed to predict self-reported affective experiences using a multi-modal set of peripheral ner...
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362
Orbital Modulation of Gamma Rays up to 100 TeV from LS 5039
Έκδοση 2025-01-01Λήψη πλήρους κειμένουGamma-ray binaries are luminous in gamma rays, composed of a compact object orbiting a massive companion star. The interaction between these two objects can drive relativistic outflows, either jets or winds, in which particles can be accelerated to energies reaching hundreds of teraelectronvolts (Te...
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363
PKS J0805-0111: A Second Owens Valley Radio Observatory Blazar Showing Highly Significant Sinusoidal Radio Variability—The Tip of the Iceberg
Έκδοση 2025-01-01Λήψη πλήρους κειμένουOwens Valley Radio Observatory observations of the supermassive black hole binary (SMBHB) candidate PKS 2131−021 revealed, for the first time, six likely characteristics of the phenomenology exhibited by SMBHBs in blazars, of which the most unexpected and critical is sinusoidal flux density variatio...
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364
Novel composite health assessment risk model for older allogeneic transplant recipients: BMT-CTN 1704
Έκδοση 2025-07-01Λήψη πλήρους κειμένουAbstract: Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for older adults with hematologic malignancies. Concerns on nonrelapse mortality (NRM) in older adults limit allo-HCT utilization. We executed a prospective, observational study BMT-CTN 1704 (Blood and Marrow...
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365
A Catalog of Galactic Supernova Remnants and Supernova Remnant Candidates from the EMU/POSSUM Radio Sky Surveys. I.
Έκδοση 2025-01-01Λήψη πλήρους κειμένουWe use data from the Evolutionary Map of the Universe (EMU) and Polarization Sky Survey of the Universe’s Magnetism (POSSUM) radio southern sky surveys, conducted with the Australian Square Kilometre Array Pathfinder (ASKAP) to compile a catalog of Galactic supernova remnants (SNRs) and candidate SN...
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366
Безопасность и эффективность авалглюкозидазы альфа по сравнению с алглюкозидазой альфа у пациентов с болезнью Помпе с поздним началом: рандомизированное многоцентровое исследование...
Έκδοση 2024-01-01Λήψη πλήρους κειμένουВведение. Болезнь Помпе – редкое прогрессирующее нервно-мышечное заболевание, вызванное дефицитом кислой альфа-глюкозидазы и накоплением гликогена в лизосомах.Цель исследования – оценить безопасность и эффективность авалглюкозидазы альфа, препарата рекомбинантного человеческого энзима кислой альфа-г...
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367
A Two-week IXPE Monitoring Campaign on Mrk 421
Έκδοση 2025-01-01Λήψη πλήρους κειμένουX-ray polarization is a unique new probe of the particle acceleration in astrophysical jets made possible through the Imaging X-ray Polarimetry Explorer. Here we report on the first dense X-ray polarization monitoring campaign on the blazar Mrk 421. Our observations were accompanied by an even dense...
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368
Timescales of Polycyclic Aromatic Hydrocarbon and Dust Continuum Emission from Gas Clouds Compared to Molecular Gas Cloud Lifetimes in PHANGS-JWST Galaxies
Έκδοση 2025-01-01Λήψη πλήρους κειμένουRecent JWST mid-infrared (mid-IR) images, tracing polycyclic aromatic hydrocarbons (PAHs) and dust continuum emission, provide detailed views of the interstellar medium (ISM) in nearby galaxies. Leveraging PHANGS-JWST Cycle 1 and PHANGS-MUSE data, we measure the PAH and dust continuum emission lifet...
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369
Relationships between Polycyclic Aromatic Hydrocarbons, Small Dust Grains, H2, and H i in Local Group Dwarf Galaxies NGC 6822 and WLM Using JWST, ALMA, and the VLA
Έκδοση 2025-01-01Λήψη πλήρους κειμένουWe present 0.6–3.2 pc resolution mid-infrared (MIR) JWST images at 7.7 μ m (F770W) and 21 μ m (F2100W) covering the main star-forming regions of two of the closest star-forming low-metallicity dwarf galaxies, NGC 6822 and Wolf–Lundmark–Melotte (WLM). The images of NGC 6822 reveal filaments, edge-bri...
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370
Cropland repurposing as a tool for water sustainability and just land transition in California: review and best practices
Έκδοση 2025-06-01Λήψη πλήρους κειμένουThere is not enough water in California to support current water uses and preserve healthy environments. California aquifers have been chronically depleted over decades, causing household water insecurity, degrading groundwater-dependent ecosystems, affecting small and medium farmers, and inducing s...
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371
EP250108a/SN 2025kg: A Jet-driven Stellar Explosion Interacting with Circumstellar Material
Έκδοση 2025-01-01Λήψη πλήρους κειμένουWe present optical, radio, and X-ray observations of EP250108a/SN 2025kg, a broad-line Type Ic supernova (SN Ic-BL) accompanying an Einstein Probe (EP) fast X-ray transient at z = 0.176. EP250108a/SN 2025kg possesses a double-peaked optical light curve, and its spectrum transitions from a blue under...
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372
Factors associated with and kinetics of anti–IFN-α autoantibodies in RAG1/2 deficiency
Έκδοση 2025-08-01Λήψη πλήρους κειμένουBackground: Autoantibodies against IFN-α (anti–IFN-α) have been reported in recombinase activating gene (RAG) deficiency, attributed to impaired central and peripheral T-cell/B-cell tolerance. However, the clinical features, especially viral infections, associated with these autoantibodies at baseli...
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373
Grand Challenges at the Interface of Engineering and Medicine
Έκδοση 2024-01-01Λήψη πλήρους κειμένουOver the past two decades Biomedical Engineering has emerged as a major discipline that bridges societal needs of human health care with the development of novel technologies. Every medical institution is now equipped at varying degrees of sophistication with the ability to monitor human health in b...
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374
First M87 Event Horizon Telescope Results. II. Array and Instrumentation
Έκδοση 2019-01-01Λήψη πλήρους κειμένουThe Event Horizon Telescope (EHT) is a very long baseline interferometry (VLBI) array that comprises millimeter- and submillimeter-wavelength telescopes separated by distances comparable to the diameter of the Earth. At a nominal operating wavelength of ∼1.3 mm, EHT angular resolution ( λ / D ) is ∼...
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375
First M87 Event Horizon Telescope Results. I. The Shadow of the Supermassive Black Hole
Έκδοση 2019-01-01Λήψη πλήρους κειμένουWhen surrounded by a transparent emission region, black holes are expected to reveal a dark shadow caused by gravitational light bending and photon capture at the event horizon. To image and study this phenomenon, we have assembled the Event Horizon Telescope, a global very long baseline interferome...
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