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  1. 1

    Effects of soy isoflavones on menopausal symptoms in perimenopausal women: a systematic review and meta-analysis by Haodi Luan, Qianqian Liu, Yahui Guo, Hua Fan, Sileng A., Jing Lin

    Published 2025-07-01

    Soy isoflavones are phytoestrogens found mainly in soy and its derivatives. Given their estrogen-like and antioxidant-inhibiting inflammatory effects, they have been hypothesized to be effective in treating menopausal symptoms. We conducted a systematic review in accordance with the PRISMA guideline...

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  2. 2

    Dinosaur track assemblages from mid-Cretaceous of Fujian Province, southeastern China: ichnotaxonomic review and faunal comparison by Lida Xing, Kecheng Niu, Qiyan Chen, Hendrik Klein, Anthony Romilio, Runsheng Chen, Min Lin, Ke Deng, Jianrong Tang

    Published 2025-06-01

    Among the the mid-Cretaceous strata in China, considerable dinosaur record are preserved in the southeastern mountainous and arc-related basins. The Shanghang Basin is one of the sporadic red-stratified basins distributed in western Fujian, SE China, and has previously been discovered as the home of...

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  3. 3

    Integrated platform for structural and functional analysis of terpene synthases of Cannabis sativa by Danielle Wiles, James Roest, Bhuvana Shanbhag, Julian Vivian, Travis Beddoe

    Published 2025-07-01

    Terpenoids are the largest and most diverse family of natural products. Volatile terpenes from Cannabis sativa are crucial in flavours, fragrances, and pharmaceuticals due to their unique odours and biological activities, including antimalarial, antibacterial, and insecticidal properties. Their synt...

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  4. 4

    Using PLUS-InVEST-OPGD model to explore spatiotemporal variation of ecosystem carbon storage and its drivers in Jinsha river basin, China by Lichang Huang, Xue Ding, Jinliang Wang, Shuangyun Peng

    Published 2025-07-01

    Land-Use/Land-Cover Change (LUCC) is a key disturbance factor of the carbon cycle in terrestrial ecosystems, and the study on the coupling mechanism between LUCC and carbon storage is of great scientific value for implementing a regional carbon-neutral strategy. In this study, the Jinsha River Basin...

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  5. 5

    Survival benefit from adjuvant chemoradiotherapy in local advanced gastric cancer without accurate D2 confirmation: a real-world retrospective study (TJ-ARK01) by Xiao-Xiao Luo, Ben Zhao, Li Sun, Yu-Hong Dai, Hong Qiu, Xiang-Lin Yuan

    Published 2025-07-01

    The role of adjuvant chemoradiotherapy (CRT) is controversial following D2 dissection in advanced gastric cancer. Also, the extent of “D2 surgery” varied geographically due to the diversity in surgical techniques of radical lymphadenectomy and pathological accuracy in detecting positive lymph nodes...

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  6. 6

    SARS-CoV-2-specific humoral and cellular immunity assessment in Peruvian vaccinated population: a cross-sectional study by Marlon Yuri Garcia-Paitan, Salyoc Tapia-Rojas, Hector Santiago Alvarez Vega, Javier Enciso-Benavides, Maria J. Pons, Ana Mayanga-Herrera

    Published 2025-07-01

    Background Evaluating both humoral and cellular immunity is essential for optimizing vaccination strategies and preventing post-pandemic SARS-CoV-2 outbreaks. This cross-sectional study assessed cellular immunity by measuring CXCL10 mRNA expression and humoral immunity through SARS-CoV-2-specific Ig...

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  7. 7

    Motor competence development of children in Singapore: a cross-sectional and longitudinal study by Jernice S.Y. Tan, Michael Y.H. Chia

    Published 2025-07-01

    Introduction Understanding the motor competence development of young children requires both cross-sectional and longitudinal analyses. This is crucial for identifying relative age effects and tracking individual developmental trajectories. However, there are limited data in Southeast Asia, particula...

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  8. 8

    Insights into the metagenomic and metabolomic compositions of the bacterial communities in Thai traditional fermented foods as well as the relationships between food nutrition and... by Pongrawee Nimnoi, Neelawan Pongsilp

    Published 2025-06-01

    Five Thai traditional fermented foods, including khao-mak (sweet fermented sticky rice), pak-kard-dong (sour salt-fermented mustard greens), nor-mai-dong (sour salt-fermented bamboo sprouts), moo-som (sour salt-fermented pork), and pla-som (sour salt-fermented fish), were analyzed for their food nut...

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  9. 9

    Effects of irrigation and nitrogen management on phyllosphere microbial communities of silage maize by Liuxing Xu, Changjing Chen, Chenggang He, Ahmed M. Abd El Tawab, Qinhua Liu, Hua Jiang

    Published 2025-07-01

    Silage maize (Zea mays) is a significant source of animal roughage in many countries. Few studies have revealed the specific impacts of agronomic measures on harmful or beneficial microbial species (based on plant health or utilization) in silage maize. The aim of the present study was to investigat...

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  10. 10

    Antibacterial potential and chromatographic profiling of bioactive compounds from endophytic Streptomyces sp. strain MIRK71 isolated from Mirabilis jalapa (L.) by Lalrokimi, Purbajyoti Deka, William Carrie, Lallawmsangi, Christine Vanlalbiakdiki Sailo, Lalrosangpuii, Felicia Lalremruati, Awmpuizeli Fanai, Yasangam Umbon, Esther Lalnunmawii, Zothanpuia

    Published 2025-07-01

    Multidrug-resistant bacteria pose an alarming global health threat. The persistent rise in antibiotic-resistant infections continues to challenge healthcare systems worldwide. This study aims to evaluate the antimicrobial potential of 18 endophytic actinobacteria isolated from Mirabilis jalapa (L.)...

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  11. 11

    A Jack of All Trades—Tawaki/Fiordland penguins are able to utilise diverse marine habitats during winter migration by Thomas Mattern, Klemens Pütz, Pablo Garcia Borboroglu, Ursula Ellenberg, David M. Houston, Bernhard Lüthi, Philip J. Seddon

    Published 2025-07-01

    Migration and non-breeding movements are common across animal groups and are often driven by seasonal changes in habitat conditions. This behaviour is prevalent in crested penguins (Eudyptes sp.), which have evolved in and still primarily inhabit the subantarctic regions of the Southern Hemisphere....

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  12. 12

    Eukaryotic gut community of the bat Myotis arescens in anthropized landscapes in Chile by Lia Ramírez-Fernández, Mónica Saldarriaga-Córdoba, Andrea X. Silva, Constanza Napolitano, Annia Rodríguez-San Pedro

    Published 2025-06-01

    Background Human-driven environmental changes can disrupt wildlife habitats, forcing animals to adapt to fragmented or degraded ecosystems. In some cases, this leads to increased proximity between wildlife and human populations, heightening the risk of pathogen spillover. Bats, as key ecological pla...

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  13. 13

    Utilizing loop-mediated isothermal amplification (LAMP) for detecting hemoglobin Constant Spring and hemoglobin Pakse mutations amidst the high prevalence and genetic heterogeneity... by Kasama Wongprachum, Nichakan Thitipoomdecha, Phakkamon Ananratanakit, Wattanakit Prakobkul, Unchasa Angkuranak, Nitchagan Sawangkul, Prapaporn Panichchob, Rossarin Karnpean, Wittaya Jomoui

    Published 2025-07-01

    Thalassemia is a genetic disorder with significant prevalence in Southeast Asia, particularly in Thailand, where hemoglobin (Hb) Constant Spring (Hb CS) and hemoglobin Pakse (Hb PS) mutations are common. These mutations, resulting from stop codon alterations in the α2-globin gene, can lead to severe...

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  14. 14

    Non-agriculturalization of cultivated land in densely populated areas at the watershed scale: a case study of the Minjiang River Basin, China by Xi Zhao, Zhongwen Hu, Yinghui Zhang, Jingzhe Wang, Tiezhu Shi, Yanguo Liu, Jie Zhang, Guofeng Wu

    Published 2025-07-01

    Zero hunger is a top priority in the Sustainable Development Goals, however, millions of people worldwide still face hunger. Over the years, China has experienced rapid population growth, industrialization and urbanization, leading to significant agricultural land loss, which threats the nation’s fo...

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  15. 15

    Vocal constraints on song amplitude in star finches Bathilda ruficauda by Hana Goto, Masayo Soma, Ayumi Mizuno, Henrik Brumm

    Published 2025-07-01

    Given the two main functions of birdsong, mate attraction and territory defence, song amplitude is crucial for communication because it determines the communication range and it can also carry information. To understand the evolution of signals, it is helpful to consider the constraints on signal pr...

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  16. 16

    Research on the application of biomaterial-based responsive hydrogels in the tumor microenvironment by Wanrong Yue, Xiaoyu Zhu, Ming Wu, Wenyue Qiang, Yixin Yang, Ziyun Zhang, Youwei Wang, Yuanyin Teng, Mi Zhou

    Published 2025-07-01

    The tumor microenvironment (TME) is a critical factor influencing the initiation, growth, and spread of solid tumors. Recent advancements highlight biomaterial-based responsive hydrogels as promising smart materials within the TME owing to their high biocompatibility, biodegradability, and sensitivi...

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  17. 17

    A predictive framework for identifying source populations of non-native marine macroalgae: Chondria tumulosa in the Pacific Ocean by James T. Fumo, Patrick K. Nichols, Taylor Ely, Peter B. Marko, Amy L. Moran, Brian S. Powell, Taylor M. Williams, Randall K. Kosaki, Celia M. Smith, Keolohilani H. Lopes Jr., Jennifer E. Smith, Heather L. Spalding, Stacy A. Krueger-Hadfield, Karla J. McDermid, Brian B. Hauk, James Morioka, Kevin O’Brien, Barbara Kennedy, Frederik Leliaert, Mutue T. Fujii, Wendy A. Nelson, Stefano G. A. Draisma, Alison R. Sherwood

    Published 2025-06-01

    The cryptogenic marine red alga Chondria tumulosa was first observed in 2016 in subtidal habitats at Manawai (Pearl and Hermes Atoll) in the Papahānaumokuākea Marine National Monument (PMNM), Hawai‘i. Without molecular or morphological matches to any known species, it was described in 2020 and decla...

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  18. 18

    Associations between meteorological factors and pregnancy complications during different pregnancy trimesters: a multicenter retrospective study in eastern China by Tao Chen, Jie Cai, Da He, Hui Zhu, Xiang Chen, Yuqiong Li, Wen Ye, Bingqi Li, Qinyan Xu, Lindan Ji, Jin Xu

    Published 2025-06-01

    Background Previous studies have demonstrated the effects of ambient temperature on the risk of pregnancy complications. However, the associations between multiple meteorological factors and pregnancy complications have rarely been studied. Methods We carried out a retrospective study on the impacts...

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  19. 19

    The quality and reliability of YouTube video content about gingival recession on different time periods by Beyza Bozoklu, Nülüfer Demir, Merve Akbaş, Hatice Sena Öner, Duygu Yaman

    Published 2025-07-01

    Background Gingival recession is a mucogingival problem that can cause esthetic concerns and sensitivity. While some patients remain unaware of it, others seek solutions through various means. The COVID-19 pandemic has increased the role of social media in accessing health information. The frequent...

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  20. 20

    CircVAMP3 promotes acute lung injury progression by regulating the miR-580-3p/STING/IFN-β axis in macrophages by Zheng Zhou, Shuyang Chen, Yajun Wang, Shujing Chen, Jinjun Jiang

    Published 2025-06-01

    Circular RNA (circRNA) is a prominent group of non-coding RNA (ncRNA) that regulates gene expression at the post-transcriptional level in various diseases including acute respiratory distress syndrome (ARDS). In our study, circVAMP3 was a novel circRNA significantly increased in macrophages in an ac...

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