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  1. 141

    Pim3 up-regulation by YY1 contributes to diabetes-induced cardiac hypertrophy and heart failure Xiao Jin, Yi Ren, Li Wang, Hao Xie, Lu Huang, Juan Zhang, Zuo-Ying Hu

    出版 2025-02-01

    Objective(s): The close relationship of proto-oncogenes to myocardial hypertrophy has long been recognized, and cardiac hypertrophy leads to heart failure (HF). However, whether proviral insertion of Moloney virus 3 kinase (Pim3), a proto-oncogene, contributes to cardiac hypertrophy in diabetes mell...

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  2. 142

    Structural and functional disconnections in non-acute post-stroke patients Yanan Wu, Chuanshuai Tian, Zhixuan Yu, Zaixing Liu, Han Wu, Jie Ming, Wenjun Hong, Rong Xu

    出版 2025-06-01

    BackgroundStructural alterations and functional reorganizations related to motor dysfunction after stroke remain unclear. This study aims to investigate alterations in structural connectivity (SC) and functional connectivity (FC) in non-acute post-stroke patients, and their associations with motor p...

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  3. 143

    4H–SiC Avalanche Photodiode Linear Array Operating in Geiger Mode Lianghui Li, Dong Zhou, Hai Lu, Wenkai Liu, Xiaofan Mo, Fangfang Ren, Dunjun Chen, Ruiqi Wang, Guanglei Li, Rong Zhang, Youdou Zheng

    出版 2017-01-01

    In this study, a 50-pixel linear array of 4H–SiC ultraviolet avalanche photodiodes operating in Geiger mode is reported for the first time. The 50 pixels within the linear array are all capable of detecting single photons but with a small number of them suffering from extra leakage curren...

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  4. 144

    Strategies for Enhancing Energy-Level Matching in Perovskite Solar Cells: An Energy Flow Perspective Xiaorong Shi, Kui Xu, Yiyue He, Zhaogang Peng, Xiangrui Meng, Fayi Wan, Yu Zhang, Qingxun Guo, Yonghua Chen

    出版 2025-06-01

    Highlights Energy transfer is systematically reviewed as a guiding principle for current materials and optimization strategies in perovskite solar cells. Characteristic mechanisms are identified to classify energy-level optimization strategies into two categories. Performance-enhancement strategies...

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  5. 145

    Occurrences, spatial distributions, and ecological risks of organic ultraviolet absorbents in surface sediments from Taihu Lake, China Wen Gu, Shuai Sun, Yinying Cai, Ziyan Du, Xiaohan Shan, Mengyuan Liang, Min Guo, Linjun Zhou, Yong Zhang

    出版 2025-06-01

    The occurrences and spatial distributions of eight organic ultraviolet absorbents (UVAs) were investigated in surface sediments from Taihu Lake, China. The detection frequencies and concentrations of UVAs in 2016 were significantly higher than those in 2015.2-Ethylhexyl methoxycinnamate and homosala...

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  6. 146
  7. 147

    Surgical Outcomes of Video‐Assisted Thoracic Surgery Combined With Computed Tomography‐Guided Microwave Ablation for Lung Cancer Presenting as Multiple Ground‐Glass Opacities: A 5‐... Bin Huang, Chuanfei Zhan, Pengcheng Yu, Yifan Xu, Muhammad Zunair Bhatti, TianMing Chen, WenDa Yin, Zhifei Ma, Chi Su, Zhongqiu Wang, Dongjie Feng, Tian Shen, Xiaokang Shen, Dongqing Lu, Lin Zheng, Shilin Chen

    出版 2025-07-01

    ABSTRACT Background Multiple ground glass opacities (mGGOs) are frequently observed in patients with early‐stage lung adenocarcinoma. The most appropriate and effective treatment for these mGGOs remains controversial. The purpose of this study was to retrospectively review the usefulness and safety...

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  8. 148

    Potential of Urinary Mutation and Methylation Biomarkers in Selecting Candidates for Repeat Transurethral Resection of Bladder Tumor in Non–muscle-invasive Bladder Cancer: A Prospe... Xiao Yang, Lingkai Cai, Yaqun Xin, Xinfeng Chen, Bing Zheng, Jie Han, Lin Yuan, Xuejian Yang, Pengchao Li, Juntao Zhuang, Peikun Liu, Ruixi Yu, Rongjie Bai, Yiyang Liu, Tonghui Ma, Qiang Cao, Qiang Lu

    出版 2025-07-01

    Background and objective: The necessity of repeat transurethral resection of bladder tumor (re-TURBT) in patients with non–muscle-invasive bladder cancer (NMIBC) remains a matter of debate. The role of liquid biopsy in predicting residual tumor status and selecting patients who can be spared re-TURB...

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  9. 149

    Molecular Cloning, Expression Analysis and Localization of Exo70A1 Related to Self Incompatibility in Non-Heading Chinese Cabbage (Brassica campestris ssp. chinensis) Li WANG, Ting-ting GE, Hai-tao PENG, Cheng WANG, Tong-kun LIU, Xi-lin HOU, Ying LI

    出版 2013-12-01

    The exocyst is a conserved protein complex, and required for vesicles tethering, fusion and polarized exocytosis. Exo70A1, the exocyst subunit, is essential for assembly of the exocyst complex. To better understand potential roles of Exo70A1 in non-heading Chinese cabbage (Brassica campestris ssp. c...

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  10. 150

    Revealing the heterogeneity of treatment resistance in less‐defined subtype diffuse large B cell lymphoma patients by integrating programmed cell death patterns and liquid biopsy Wei Hua, Jie Liu, Yue Li, Hua Yin, Hao‐Rui Shen, Jia‐Zhu Wu, Yi‐Lin Kong, Bi‐Hui Pan, Jun‐Heng Liang, Li Wang, Jian‐Yong Li, Rui Gao, Jin‐Hua Liang, Wei Xu

    出版 2025-01-01

    Abstract Precision medicine in less‐defined subtype diffuse large B‐cell lymphoma (DLBCL) remains a challenge due to the heterogeneous nature of the disease. Programmed cell death (PCD) pathways are crucial in the advancement of lymphoma and serve as significant prognostic markers for individuals af...

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  11. 151

    Experimental Study of the Resonant Response of Monolayer Colloidal Crystal Waveguide by Symmetric Probing Wenxiu Wang, Wenjian Zhang, Hui Hao, Zhanwu Xie, Liya Liu, Wei Xia, Haitao Yan

    出版 2024-01-01

    The extra-interfacial manifestations induced by the waveguide resonance properties of monolayer colloidal crystals (MCCs) have been well discovered by symmetrically probing their reflectance spectra. To clearly analyze the origin of the resonance peaks in the spectra obtained by reflection probing,...

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  12. 152

    Exploration of Embodied Teaching Mode in Medical Philosophy Curriculum Hong LIU, Zhaoheng YUN, Jianwen SHAO, Yuanyuan YAO, Yiyi WU, Yixin WU, Yuyu GUO

    出版 2025-03-01

    The conjugation of embodied teaching and disembodied teaching to enhance instructional quality is an innovative reform measure in medical philosophy education. The teaching objectives of medical philosophy curriculum should shift from being "mind-centered" to "body-centered", the...

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  13. 153

    Gene‐Smoking Interaction in Insulin Sensitivity and β‐Cell Function Among Normal Glucose Tolerance Individuals Pan Gu, Shuai Zheng, Sijie Zhang, Jie Yuan, Hao Hong, Jinglan Dai, Jingyi Zhao, Kuanfeng Xu, Tao Yang, Qi Fu, Sipeng Shen, Hao Dai

    出版 2025-07-01

    ABSTRACT Objective To identify genetic loci that exhibit potential interactions with smoking status on insulin sensitivity and islet β‐cell function within normal glucose tolerance (NGT) populations. Methods All participants underwent an OGTT to confirm NGT status, followed by assessments of insulin...

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    “...Analyses were performed in NGT participants from Nanjing (N = 4808) and Jurong (N = 508) for discovery and validation, respectively. ...”
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  14. 154

    Genome-Wide Comparative Analysis of Invertases in the <i>Salicaceae</i> with the Identification of Genes Involved in Catkin Fiber Initiation and Development Hui Wang, Qianhua Tang, Jinyan Mao, Chang Jia, Zilu Qin, Yiqun Chen, Qingqing Liang, Xiaogang Dai, Yingnan Chen, Tongming Yin, Huaitong Wu

    出版 2025-06-01

    Invertase (INV) irreversibly converts sucrose to glucose and fructose during processes such as differentiation and organ development in plants, especially during the development of trichomes. Systematic identification and analysis of INVs in Salicaceae remain limited. Here, <i>INV</i> ge...

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  15. 155

    AhR deficiency exacerbates inflammation in diabetic wounds via impaired mitophagy and cGAS-STING-NLRP3 activation: Therapeutic potential of hydrogels loaded with FICZ Yingying Wang, Tianyi Ni, Qian Zhang, Zibo Xu, Zhechen Zhu, Jiaheng Xie, Min Yi, Liying Tu, Zexiong Cheng, Yiwen Gao, Haowen Xu, Wei Yan, Jingping Shi

    出版 2025-10-01

    Delayed healing of diabetic foot ulcers (DFUs) is driven by chronic inflammation and mitochondrial dysfunction. We identify the aryl hydrocarbon receptor (AhR) as a key regulator of immune and mitochondrial homeostasis in diabetic wounds. AhR expression was elevated in macrophages from human and mur...

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  16. 156

    Storage stability and safe storage life assessments of gradiently denitrated spherical gun propellants Gang Wang, Hao Chen, Shi-ying Li, Qi Yang, Yu-dong Shi, Ya-jun Ding, Zhong-liang Xiao

    出版 2025-06-01

    As a new type of gun propellant, Gradiently denitrated spherical gun propellants (GDSP) demonstrate excellent progressive combustion performance and clean combustion performance. However, its unknown storage performance hinders its application, necessitating thorough research. In this study, three t...

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  17. 157

    Hybrid Cyan Nitride&#x002F;Red Phosphors White Light-Emitting Diodes With Micro-Hole Structures Tao Tao, Ting Zhi, Xu Cen, Bin Liu, Qi Wang, Zili Xie, Peng Chen, Dunjun Chen, Yugang Zhou, Youdou Zheng, Rong Zhang

    出版 2018-01-01

    Hybrid white light emitting diodes (LEDs) have been developed utilizing micro-LEDs radiatively pumping down-conversion phosphor materials. The cyan InGaN&#x002F;GaN multiple quantum wells LEDs with 95 &#x03BC;m in square are fabricated into 4 &#x00D7; 4 pixels as one unit in 4 in wafer b...

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  18. 158

    Broad-Spectrum Virus Elimination by Nasal Mucosa-Colonized Wild-Type Bacillus subtilis Yuchen Li, Chengjie Yang, Rongfeng Tang, Chengcheng Wang, Yunfeng Li, Wenwen Chao, Ahui Cui, Chun Liang, Ying Duan, Hui Zeng, Qian Yang

    出版 2025-01-01

    Outbreaks and the widespread prevalence of porcine respiratory infectious diseases have led to substantial economic losses worldwide. In this study, epidemiological surveillance revealed lower viral detection in association with an increased abundance of Bacillaceae in pigs with outdoor access; thus...

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  19. 159

    Intestinal microbiota changes in early life of very preterm infants with bronchopulmonary dysplasia: a nested case–control study Tao Ning, Tao Ning, Xiaoxue Shan, Xiaowen Zhuang, Bingjie Li, Yuhan Zhang, Tianyu Chen, Song Peng, Han Lu, Qiong Xue, Huaiyu Yan, Yimei Ren, Shudong Cui, Xiaoqing Chen

    出版 2025-07-01

    Background and aimBronchopulmonary dysplasia (BPD) is one of the most important complications of very preterm infants. This study was to investigate changes in the intestinal microbiota of very preterm infants with BPD.MethodsWe enrolled 50 very preterm infants at the gestational age of 24+0–31+6 we...

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  20. 160

    Characterize the Speed of a Photon-Number-Resolving Superconducting Nanowire Detector Xu Tao, Hao Hao, Xiang Li, Shi Chen, Libo Wang, Xuecou Tu, Xiaoqing Jia, Labao Zhang, Qingyuan Zhao, Lin Kang, Peiheng Wu

    出版 2020-01-01

    Superconducting series nanowire single-photon detectors (SNDs) have been used for resolving photon numbers. But it can also exhibit a higher counting rate than a single superconducting nanowire single-photon detector (SNSPD), because the serial architecture allows multiple detectors working in paral...

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