Αποτελέσματα αναζήτησης - "Nanjing"
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Noninvasive diagnosis of significant liver inflammation in patients with chronic hepatitis B in the indeterminate phase
Έκδοση 2023-12-01Λήψη πλήρους κειμένουThe presence of significant liver inflammation is an important indication for antiviral treatment in patients with chronic hepatitis B (CHB) in the indeterminate phase. We aimed to establish a non-invasive nomogram to predict significant liver inflammation in these patients. A total of 195 CHB patie...
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122
Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome
Έκδοση 2025-07-01Λήψη πλήρους κειμένουAbstract Aberrant activation of the NACHT, LRR, and PYD domain‐containing protein 3 (NLRP3) inflammasome contributes to the pathogenesis of fatal and perplexing pulmonary diseases. Although pharmacological inhibition of the NLRP3 inflammasome brings potent therapeutic effects in clinical trials and...
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123
Efficacy and safety of upadacitinib for patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis
Έκδοση 2025-07-01Λήψη πλήρους κειμένουObjectiveThere is a growing array of options for the treatment of immune-mediated inflammatory diseases (IMIDs). To explore upadacitinib’s efficacy and safety in autoimmune disease treatment, we conducted this study.MethodsPubmed, Web of Science and Embase were searched for randomized controlled tri...
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124
Integrated physiological, metabolomic, and transcriptomic responses of maize (Zea mays) and soybean (Glycine max) to nanoplastic-induced stress
Έκδοση 2025-09-01Λήψη πλήρους κειμένουThe widespread use and degradation of agricultural plastics lead to the accumulation of nanoplastics (NPs) and soil contamination, posing growing risks to agroecosystems. This study investigated the differential physiological and molecular responses of maize (Zea mays) and soybean (Glycine max) to p...
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125
Association between sensitivity to thyroid hormone indices and frailty in the elderly: a cross-sectional study
Έκδοση 2025-07-01Λήψη πλήρους κειμένουObjectiveFrailty is a prevalent geriatric syndrome that affects several systems and lacks accurate evaluation indications. Previous studies on the association between thyroid function and frailty have contradicted. This study introduced the thyroid hormone sensitivity indices to analyze their connec...
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126
Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review
Έκδοση 2025-07-01Λήψη πλήρους κειμένουAbstract Cardiovascular diseases (CVDs), such as ischemic heart disease and stroke—both driven by thrombotic events—are the predominant cause of global mortality. Conventional treatments, including systemic thrombolysis and mechanical thrombectomy, face challenges such as bleeding risks and complica...
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127
Technical and environmental efficiency of hog production in China – A stochastic frontier production function analysis
Έκδοση 2015-06-01Λήψη πλήρους κειμένουThis article analyses the technical and environmental efficiency of hog production in China using data from the China Agricultural Product Cost-Benefit Compilation (NDRC 2005–2013) and the First National Census of Pollution: Manual of Discharge Coefficient of Livestock and Poultry Industry (IEDA and...
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128
Nuclear localization of platelet activating factor receptor accounts for microglial phagocytosis in ischemic stroke
Έκδοση 2025-09-01Λήψη πλήρους κειμένουIschemic stroke (IS) is a leading cause of global morbidity and mortality. A critical strategy for improving the prognosis of IS involves mitigating neuronal loss to enhance neuroplasticity, with microglia playing a vital role in neuronal survival. The platelet activating factor receptor (PTAFR) par...
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129
RETRACTED ARTICLE: The Notch signal mediates macrophage polarization by regulating miR-125a/miR-99b expression
Έκδοση 2019-12-01Λήψη πλήρους κειμένουWe, the Editor, Publisher, and Authors of Artificial Cells, Nanomedicine and Biotechnology, have retracted the following article:Qian Li, Xia He, Qiao Yu, Yuan Wu, Mingyu Du, Jing Chen, Fanyu Peng, Wenjun Zhang, Jie Chen, Yan Wang, Hanbo Chen, Hairong Wang, Dan He & Qiang Wang. (2019). The Notch...
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130
Metagenomic next-generation sequencing-based characterization of the viral spectrum in clinical pulmonary and peripheral blood samples of patients
Έκδοση 2025-07-01Λήψη πλήρους κειμένουBackgroundMetagenomic next-generation sequencing (mNGS) enables comprehensive profiling of viral communities in clinical samples. However, comparative analyses of the virome across anatomical compartments and disease states remain limited. This study aims to characterize the virome in bronchoalveola...
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131
pH-Responsive multifunctional drug-loaded covalent organic framework hydrogel dressing for enhanced bacteria-infected wound healing
Έκδοση 2025-09-01Λήψη πλήρους κειμένουPathogen-induced delayed wound healing remains a formidable public health challenge. Traditional smart antibiotic delivery systems that spontaneously generate electrical signals to enhance antibacterial efficacy typically require metal electrodes connected to an external power source, thereby limiti...
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132
Bioinformatics analysis of type II toxin–antitoxin systems and regulatory functional assessment of HigBA and SS-ATA in Streptococcus suis
Έκδοση 2025-05-01Λήψη πλήρους κειμένουToxin–antitoxin (TA) systems, which are prevalent in bacteria and archaea, play diverse roles in bacterial physiology and have been proposed to be significant in stress adaptation. Despite the extensive characterization of numerous TA systems in various bacteria, the investigation of these systems w...
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133
The deep detoxification of tetrabromobisphenol a in a hybrid reactor system: Iron-based trimetallic and aerobic activated sludge methods
Έκδοση 2025-06-01Λήψη πλήρους κειμένουTetrabromobisphenol A (TBBPA) is prevalent in various environmental media and biological matrices, posing considerable ecological and health risks due to its endocrine-disrupting, immunotoxic, neurotoxic, and carcinogenic properties. In this study, we developed an advanced mineralization process for...
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134
DNA methylation in esophageal cancer: technological advances and early detection clinical applications
Έκδοση 2025-07-01Λήψη πλήρους κειμένουEsophageal cancer (EC) is a malignant tumor with high mortality rates, where early screening and diagnosis are critical for improving patient outcomes. DNA methylation, a key epigenetic modification, has emerged as a significant biomarker for early detection of EC. The advancement in DNA methylation...
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135
Association of bioelectrical impedance phase angle and nutritional status in patients undergoing pancreaticoduodenectomy
Έκδοση 2025-07-01Λήψη πλήρους κειμένουBackgroundVarious tools for nutritional assessment are used in individuals undergoing pancreaticoduodenectomy (PD), causing varying prevalence rates of malnutrition. This may explain the causal link between nutrition status and clinical outcomes. Phase angle (PhA), a derived metric obtained from bio...
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136
Environmental aminomethylphosphonic acid (AMPA) exposure increased the risk of spontaneous abortion through lactate-induced JunB lactylation in trophoblast
Έκδοση 2025-09-01Λήψη πλήρους κειμένουThe etiology of spontaneous abortion (SA) is complex, and the underlying mechanisms remain largely elusive. Environmental toxins have been implicated in the increased occurrence of SA. However, the association between aminomethylphosphonic acid (AMPA) exposure and SA has not yet been established. We...
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137
Design and Analysis of Asymmetric Capsule-Shaped Metallic Cavities for Unidirectional Waveguide Coupling
Έκδοση 2020-01-01Λήψη πλήρους κειμένουWe propose and numerically investigate a novel asymmetric capsule-shaped metallic cavity (ACMC) structure for unidirectional waveguide coupling. By introducing cylindrical facets at cavity ends with different radius, asymmetric resonant mode is confined inside the cavity so that the evanescent energ...
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138
MiR-138: A promising therapeutic target for cancer
Έκδοση 2017-04-01Λήψη πλήρους κειμένουMicroRNAs are small noncoding RNAs which regulate gene expressions at post-transcriptional level by binding to the 3′-untranslated region of target messenger RNAs. Growing evidences highlight their pivotal roles in various biological processes of human cancers. Among them, miR-138, generating from t...
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139
A Self-Amplified Near-Infrared Bipolar Phototransistor With a PbSe Nanoband Array Heterostructure for Pharmaceutical Solute Detection
Έκδοση 2024-01-01Λήψη πλήρους κειμένουThis paper introduces a new device concept and outlines the fabrication process of a bipolar junction transistor based on an IGZO/NiO/PbSe nanoband array heterostructure. We performed comprehensive electrical property testing and characterization analysis on the device to thoro...
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140
The comparative analysis and identification of secondary metabolites between Tibet wild and cultivated pomegranates (Punica granatum L.) in China
Έκδοση 2022-03-01Λήψη πλήρους κειμένουSecondary metabolites are closely related to the nutritional quality and health functions of plants. We investigated the secondary metabolites of both wild (n=23) and cultivated (n=27) pomegranate plants (Punica granatum L.) growing in China. The total flavonoid (TF) and tannin (TT) contents from th...
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