Search Results - "Microbiota"

Introduction. The microbiota dynamics of the core biotopes during pregnancy are hardly studied, although changes in these compartments have an important role in both the functioning of the female organism and foetal development.Objective. To study the dynamics and interactions of changes in bladder,...

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Bronchial asthma (BA) remains one of the most common chronic respiratory diseases in childhood. BA develops with a combination of genetic predisposition and environmental factors. Epidemiological data on the development of BA emphasize the role of early-life microbiota in the formation of immune res...

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ABSTRACT This study aims to examine the specific relationships between gut, oral, and vaginal microbiota and the frozen embryo transfer (FET) process. Patients undergoing fertility treatment who met the inclusion criteria were included in this study. After sampling at three time points, participants...

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The upper gastrointestinal (uGI) microbiota has been implicated in infectious, metabolic, and immunological conditions, yet remains poorly characterized due to invasive sampling and low microbial biomass. We developed and validated a contamination-controlled 16S rRNA gene and transcript-based protoc...

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Alopecia areata (AA) is a complex autoimmune disorder with multifactorial pathogenesis. Recent research highlights the gut microbiota as a possible key player in AA pathogenesis through the gut–skin axis: gut dysbiosis may disrupt intestinal barrier integrity and immune tolerance by affecting T regu...

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The female genital microbiota plays a critical role in reproductive health and has recently emerged as a key factor influencing the outcomes of Assisted Reproductive Techniques (ARTs). Beyond traditional concerns about vaginal dysbiosis and infections such as bacterial vaginosis or mycoses, recent e...

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BackgroundAnimal farming may affect the structure and diversity of gut microbiota of farm workers, but it needs more studies to provide solid evidence. ObjectiveTo analyze the diversity characteristics of gut microbiota in dairy farm workers, dairy cows, and the control population (non-animal contac...

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Objective: to study the microbiota of the vagina, myomatous nodes, their bed in patients with fibroids. Materials and methods: a comprehensive examination of 83 patients aged 26 to 50 years with diagnosed interstitial, interstitial-subserous uterine myoma was carried out. By age, all women are divid...

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Autoimmune diseases are characterized by dysregulation of immune responses and damage to healthy body tissues. Their complete cure remains elusive, and existing therapies are often accompanied by side effects. Recent studies have shown a signifi cant role of disturbances in the composition of the mi...

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This paper is aimed at investigating the microbiota of the esophagus and stomach in patients with gastroesophageal reflux disease (GERD) and healthy volunteers.Materials and methods.  The study included 15 patients suffering from GERD and 6 healthy volunteers. All subjects underwent sampling of esop...

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Owing to advancements in next-generation sequencing and non-culture-based microbial research techniques, we have recognized that many bacterial taxa other than Helicobacter pylori (H. pylori) are present in the human stomach. Gastric microbial composition depends on gastric diseases, including gastr...

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Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by amyloid-beta (Aβ) plaques, tau hyperphosphorylation, and chronic neuroinflammation. While neuroinflammation—mediated by microglial and astrocyte activation—has long been considered a secondary response to Aβ pathol...

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The gut microbiome is a variable system that not only adapts to signals and information coming from humans, but also affects its host due to a complex system of interactions of living microorganisms, phages, viruses, plasmids, mobile genetic elements, molecules synthesized by microorganisms, includi...

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Researchers are increasingly focusing on understanding the microbiota’s influence on disease susceptibility and overall health. The vast number of microorganisms in our gastrointestinal tract and their extensive surface area underscore their undeniable impact on well-being. Viewing the gut microbiom...

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Endometriosis (EMS) is a long-term inflammatory disease. It represents one of the most prevalent gynecological conditions, impacting an estimated 5% of reproductive women. Therefore, endometriosis contributes to substantial worldwide health challenges and healthcare costs. In EMS disease, endometria...

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Abstract Recent evidence suggests a more important role of the gut microbiota in neurodegenerative diseases (NDDs) given its relationship through the microbiota‐gut‐brain as an active communication system aiding in maintaining homeostasis between the brain and the gut. This review focuses on how mod...

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Abstract Background The composition of the intestinal flora and the resulting metabolites affect patients' sleep after surgery. Methods We intended to elucidate the mechanisms by which disordered intestinal flora modulate the pathophysiology of postoperative sleep disturbances in hosts. In this...

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Abstract Extensive evidence demonstrates that a healthy and well-balanced gut microbiota profoundly influences host nutrient absorption, immunity, and metabolism. Unlike mammals, early microbiota colonization in commercial poultry largely depends on the environment as chicks hatch in incubators unde...

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The gut microbiota and its metabolites play important roles in the pathogenesis of various diseases. The diversity of the gut microbiota is closely related to the development and function of the human immune system. Dysbiosis, characterized by alterations in the species, quantity, and distribution o...

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