Torthaí cuardaigh - "Lung function"
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161
Asthma and COPD Overlap Syndrome (ACOS): A Systematic Review and Meta Analysis.
Foilsithe / Cruthaithe 2015-01-01“…We found no significant difference between ACOS and COPD in terms of gender, smoking status, lung function and 6mWD. However, in comparison to subject with only COPD, ACOS subjects were significantly younger, had higher BMI, healthcare utilization, and lower HRQoL.…”<h4>Background</h4>The combination of asthma and chronic obstructive pulmonary disease (COPD), or ACOS is a recently defined syndrome. The epidemiology of the condition is poorly described and previous research has suggested ACOS is associated with worse outcomes than either condition al...
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162
Predictive Biomarkers and Novel Treatments for the Progressive Fibrosing Phenotype in Interstitial Lung Disease Associated with Connective Tissue Disease
Foilsithe / Cruthaithe 2025-06-01“…Therapeutic agents such as nintedanib and pirfenidone show efficacy in slowing lung function decline. Biologics including rituximab and tocilizumab offer additional options, particularly in immunologically active diseases. …”Progressive fibrosing interstitial lung disease (PF-ILD) is a significant complication of connective tissue diseases (CTDs), particularly in systemic sclerosis (SSc), rheumatoid arthritis (RA), and idiopathic inflammatory myopathies (IIM). Despite clinical similarities with idiopathic pulmonary fibr...
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163
Effects of inspiratory muscle training on respiratory function, diaphragmatic thickness, balance control, exercise capacity and quality of life in people after stroke: A randomized...
Foilsithe / Cruthaithe 2025-01-01“…<h4>Discussion</h4>Results of this study will primarily inform the effect of IMT on lung function, balance control, exercise capacity and QOL in addition to physical rehabilitation, further the interplay between the change in diaphragm thickness, balance and QOL will be analysed in detail.…”<h4>Background</h4>Stroke is associated with diaphragmatic weakness and impaired respiratory function as well as balance impairment. The role of inspiratory muscle training (IMT) on improvement of respiratory muscle strength in people after stroke has been reported. However, the training...
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164
Moxonidine in combined therapy of essential arterial hypertension patients with chronic obstructive pulmonary disease
Foilsithe / Cruthaithe 2006-08-01“…It provides effective BP control, as well as improves heart rate variability and BP improvement, without affecting lung function, or blood levels of uric acid and glucose.…”Aim. To study moxonidine and calcium antagonist (amlodipine) effectiveness in essential arterial hypertension (EAH) treatment among patients with chronic obstructive pulmonary disease (COPD), and therapy effects on concomitant dyslipidemia. Material and methods. In total, 30 patients with EAH and St...
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165
Evaluation of radiographic pulmonary artery diameter and echocardiographic pulmonary artery pressure in COPD patients in South-West Nigeria
Foilsithe / Cruthaithe 2025-07-01“…A mean right descending pulmonary artery diameter (RDPAD) on chest radiographs (CXR), mean pulmonary arterial pressure (mPAP) on echocardiograms, and lung function on Spirometry were evaluated. Student t-test, Chi-square, and ANOVA were used to test these two groups‘ differences to determine PH. …”Background and Objective: Cardiac comorbidity is an important prognostic factor in chronic lung diseases. The presence of pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) is associated with higher morbidity and mortality, with an increased risk of exacerbations, compared w...
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166
Pneumonia and bacteremia due to Pseudomonas aeruginosa in a primary ciliary dyskinesia patient with DNAH5 variants: A case report
Foilsithe / Cruthaithe 2025-01-01“…Genetic variants of DNAH5 exhibit variable impacts on lung function and contribute to dysfunction of respiratory cilia. …”Ciliary motility disorders can be inherited or acquired. DNAH5, located on chromosome 5p15.2 and encoding a protein of 4624 amino acids, is one of the most frequently implicated genes in congenital conditions known as primary ciliary dyskinesia (PCD). Genetic variants of DNAH5 exhibit variable impac...
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167
Efficiency of Use of the «Lung Opening» Maneuver Under Artificial Ventilation in Patients With Acute Respiratory Distress Syndrome
Foilsithe / Cruthaithe 2006-08-01“…It has been found that there is a more effective recovery of lung function, less AV timing, and a shorter length of stay in a intensive care unit in patients with acute respiratory distress syndrome in whom the «lung opening» maneuver is regularly (4—6 times daily) used under AV than in those undergoing a traditional support in accordance with the principles of safe AV. …”The paper provides the results of use of the «lung opening» maneuver under artificial ventilation (AV) in adult patients with acute respiratory distress syndrome of various genesis. It shows it possible to improve gas exchange by this method in severe acute respiratory failure of the parynchematous...
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168
The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease
Foilsithe / Cruthaithe 2025-07-01“…Correlation analysis was carried out between CT score and pulmonary function index, and the lung function parameters of patients at three grades were compared between groups and pairwise among the means. …”Objective: To assess whether there is a correlation between CT scan severity score and pulmonary function in Interstitial Lung Disease, and provide a more reliable basis for clinical diagnosis and treatment. Materials and Methods: Sixty patients with clinical diagnosis of Interstitial Lung Disease (...
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169
Autologous hematopoietic stem cell transplantation in the treatment of systemic sclerosis. Part 1. Clinical aspects
Foilsithe / Cruthaithe 2020-11-01“…Auto-HSCT produces better results that can provide a more favorable long-term prognosis of SSc; it can prevent worsening of organ damages and improve skin scores and lung function. Patients with early diffuse SSc, a rapidly progressive course, and poor prognostic factors in the first 4–5 years of the disease before the development of functional insufficiency of the vital organs can be considered most promising for auto-HSCT.…”Diffuse cutaneous systemic sclerosis (SSc) characterized by an acute, rapidly progressive course and severe damage to the internal organs has an unfavorable prognosis, while the treatment of this often fatal type of the disease has not been sufficiently developed. This paper reviews an update on an...
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170
The effects of benralizumab on lung volume changes during exercise in experimental setting in severe asthmatics: a pilot study
Foilsithe / Cruthaithe 2025-07-01“…Assessments of asthma control and quality of life, lung function evaluation and 6-min walk test (6MWT) were carried out on the day of the first drug administration (T0) and after a period of 6 months (T1).ResultsTwelve severe asthmatics were recruited. …”IntroductionThe most severe forms of asthma are characterised by the occurrence of dyspnoea on exertion, impacting on daily activities and quality of life. It has been demonstrated that dynamic hyperinflation (DH) during exercise represents a mechanism of physical activity limitation in severe asthm...
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171
Comparison of respiratory muscle activities and cardiovascular function during different breathing types in healthy adults: Costal breathing, flow incentive spirometry, and volume...
Foilsithe / Cruthaithe 2025-01-01“…<h4>Background</h4>Various breathing exercises are used to enhance lung function. However, many patients have reported experiencing breathlessness and an increased work of breathing during their use, but evidence supporting this is limited. …”<h4>Background</h4>Various breathing exercises are used to enhance lung function. However, many patients have reported experiencing breathlessness and an increased work of breathing during their use, but evidence supporting this is limited. This study aimed to compare respiratory muscle...
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172
Insufficiency of Medical Care for Patients with Acute Respiratory Failure
Foilsithe / Cruthaithe 2017-09-01“…The basic defects in conducting mechanical ventilation were associated with improper lung function evaluation, microbiological tests of sputum and radiology. …”The purpose of the research: to analyze insufficiency of medical care for patients with acute respiratory failure in the ICU.Materials and methods. It was a retrospective study of 160 patients' medical records (age from 15 to 84 years) with acute respiratory failure (ARF) hospitalized in the IC...
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173
CYTOKINE PROFILE FEATURES IN THE PATIENTS WITH NONALLERGIC BRONCHIAL ASTHMA WITH CO-EXISTING TYPE 2 DIABETES MELLITUS
Foilsithe / Cruthaithe 2017-07-01“…Hence, the patients with coexistence of non-allergic bronchial asthma and DT2 were characterized by a specific cytokine profile of pro- and anti-inflammatory cytokines, which may correlate with increased glycation and deterioration of lung function.…”Thirty-five patients with non-allergic bronchial asthma (NABA), 22 patients with NABA and diabetes mellitus type 2 (DT2), 23 subjects with DT2, and 31 healthy controls were enrolled into the study. ELISA assays for IL-4, IL-10, IL-6, IFNγ were performed by means of a standardized protocol using immu...
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174
Сentral heamodynamic сondition and morphological characteristics of lungs at patients with lung cancer depending on components of the infusion-transfusion therapy
Foilsithe / Cruthaithe 2015-12-01“…The aim of this study is to determine the central hemodynamics parameters depending on the condition of ventilate lung function in thoracic oncology patients during the postoperative period and to determine the morphological features of the lungs that developed under the influence of intraoperative administration of refortan and perftoran. …”Background. Despite the large number of studies devoted to the study of the functional state of the cardiovascular and respiratory systems after operations on the lungs, there are still many issues regarding the mechanisms of hemodynamic disorders in the postoperative period. It stipulates considera...
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175
ALVEOLAR RECRUITMENT MANEUVER FOR ROBOT-ASSISTED LAPAROSCOPIC SURGERY IN TRENDELENBURG POSITIONING
Foilsithe / Cruthaithe 2025-07-01“…This study aims to evaluate the effect of the alveolar recruitment maneuver on intraoperative lung function in patients undergoing robot-assisted surgery in the Trendelenburg position. …”Purpose. This study aims to evaluate the effect of the alveolar recruitment maneuver on intraoperative lung function in patients undergoing robot-assisted surgery in the Trendelenburg position. Materials and methods. A prospective, single-center randomized study was conducted at University Hospital...
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176
Evaluating the Significance of Inspiratory Volumes and Capacity in Chronic Obstructive Pulmonary Disease
Foilsithe / Cruthaithe 2025-07-01“…Spirometry was performed to correlate lung function with serum SPD levels. We developed a regression model to assess the relative contribution of each variable to the inspiratory functions. …”Background: Smoking-induced Chronic obstructive pulmonary disease (COPD) is a chronic lung condition causing airflow obstruction and inflammation, leading to symptoms like breathlessness and fatigue. While expiratory issues are well-studied, the impact of inspiratory function on symptoms is less un...
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177
Loss of appetite in patients with chronic obstructive pulmonary disease - a mixed methods study
Foilsithe / Cruthaithe 2025-12-01“…Among the interviewed patients, the following factors influenced their appetite: Lack of daily routine, insufficient knowledge on nutrition, lack of social contact, bodily limitations, inadequate help and support, limited physical activity and lack of acceptance of life situation.Conclusion Patients with loss of appetite are characterized by a low BMI, impaired lung function, more symptoms and live alone. Improvement in social contact and support, nutritional support, and acceptance of their current life situation will help address these challenges.…”Background Loss of appetite in patients with COPD can lead to malnutrition, which is associated with an increased risk of morbidity and mortality.Aims To identify factors associated with loss of appetite among COPD patients and explore their’ experiences regarding appetite and eating.Methods A quest...
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178
CARDIO-RESPIRATORY SYSTEM IN LATE REHABILITATION PERIOD AFTER CORONARY ARTERY BYPASS GRAFT SURGERY
Foilsithe / Cruthaithe 2012-06-01“…Cardiovascular status was assessed using echocardiography (EchoCG) and Holter electrocardiography (ECG) monitoring. Lung function (LF) measurement was used for the assessment of respiratory status. …”Aim. To identify specific features of cardio-respiratory status in the late rehabilitation period after coronary artery bypass graft surgery (CABG). Material and methods. The study included 25 men (mean age 55,7±6,1 years), who underwent CABG more than 3 years ago. Functional class (FC) of angina an...
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179
Targeted Biologic Therapies in Severe Asthma: Mechanisms, Biomarkers, and Clinical Applications
Foilsithe / Cruthaithe 2025-07-01“…Monoclonal antibodies targeting IgE (omalizumab) and IL-5 (mepolizumab, benralizumab, reslizumab, depemokimab) have demonstrated the ability to reduce exacerbation frequency and improve lung function, with newer agents such as depemokimab offering extended dosing intervals. …”Asthma represents a heterogeneous disorder characterized by a dynamic balance between pro-inflammatory and anti-inflammatory forces, with allergic sensitization contributing substantially to airway hyperresponsiveness and remodeling. Central to its pathogenesis are cytokines such as IL-4, IL-5, IL-1...
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180
COUPLED PLASMAFILTRATION AND ADSORPTION IN SEPTIC COMPLICATIONS IN RENAL TRANSPLANT RECIPIENTS
Foilsithe / Cruthaithe 2014-05-01“…In patients of both groups we observed improvement of hemodynamics and lung function. In doing so by the fifth day after the second procedure in patients of the main group the results were significantly better. …”In the article first experience with the usage of coupled plasmafiltration and adsorption in the treatment of sepsis in patients after kidney transplantation has been presented. Aim: to make a comparative assessment of the impact of hemofiltration and coupled plasmafiltration and adsorption (CPFA) o...
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