Søgeresultater - "Lung function"
-
81
CLINICAL AND FUNCTIONAL FEATURES AND CHARACTERISTICS OF THE CONTROL OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN OVERWEIGHT
Udgivet 2015-08-01“...The presence of obesity leads to a deterioration of the lung function parameters and associated with significantly reduces of asthma control and quality of life of patients with chronic obstructive pulmonary disease. ...”The problem of overweight prevalence is becoming increasingly important not only in countries with high living standards, but also in developing countries, especially among the urban population. The social significance of obesity is determined by the risk of chronic non-communicable diseases in youn...
Få fuldtekst
Article -
82
Impact of Low Hand Grip Strength on Quality of Life, Utilization of Healthcare, and Mental Health in Individuals with Airflow Limitation
Udgivet 2025-07-01“...These issues were more pronounced in people with reduced lung function and low physical activity. Our findings underscore the importance of muscle strength for better quality of life, particularly in those with impaired lung function and sedentary lifestyles, suggesting that regular physical activity including muscle-strengthening exercises may improve quality of life.Keywords: chronic obstructive pulmonary disease, lung diseases, obstructive, sarcopenia, muscle strength...”Sang Hyuk Kim,1,2,* Sungmin Zo,3,* Sung A Kong,4 Ju hee Cho,5 Jong Geol Do,6 Sun Hye Shin,7 Hye Yun Park7 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Dongguk University Gyeongju Hospital, Dongguk University College of Medicine, Gyeongju...
Få fuldtekst
Article -
83
The origin of dyspnea and its role in the reduction of exercise endurance in patients with rheumatoid arthritis
Udgivet 2010-12-01“...No correlation was found between lung function parameters and blood gas composition. Pulmonary MSCT in RA patients with dyspnea more frequently revealed signs of bronchiolitis and lesion of the lung as its interstitial fibrotic type. ...”Objective. To study the prevalence and origin of dyspnea in patients with rheumatoid arthritis (RA) and to specify its impact on exercise endurance (EE) and quality-of-life (QL) indices. Subjects and methods. One hundred and four patients with RA and 100 patients without RA and chronic respiratory d...
Få fuldtekst
Article -
84
Role of home-based pulmonary rehabilitation programs for disease progression and quality of life in patients with stable bronchiectasis: a single-center RCT
Udgivet 2025-07-01“...The effects of the program on quality of life, lung function indicators, and the frequency of acute exacerbations were assessed.ResultsPreliminary findings indicate that the home-based pulmonary rehabilitation program significantly improved quality of life scores, enhanced lung function, and reduced the frequency of acute exacerbations (p < 0.05).ConclusionThe home-based pulmonary rehabilitation program is an effective intervention for patients with stable bronchiectasis, contributing to improved clinical outcomes and quality of life....”ObjectiveThis study aims to evaluate the effectiveness of a home-based pulmonary rehabilitation program for patients with stable bronchiectasis in improving their quality of life and reducing acute exacerbations.MethodsA randomized controlled trial design was employed, with patients randomly assigne...
Få fuldtekst
Article -
85
Effect of rituximab on heart involvement in systemic sclerosis
Udgivet 2019-01-01“...At the same time, a significant increase in left ventricular ejection fraction (EF) and a reduction in the severity of dyspnea was achieved, which correlated with improved lung function (a significant rise in forced vital capacity). ...”As of now, there has been a great body of data on the use of rituximab (RTM) in systemic sclerosis (SS), mainly on its positive effect on skin fibrosis and lung injury. However, information is still scarce about the effect of RTM on other organs and systems, namely the heart affected by SS.Objective...
Få fuldtekst
Article -
86
A Study of CO Emission Sources and Their Impacts on the Respiratory Systems of Patients in Al-Muthanna Governorate
Udgivet 2025-06-01“...Health assessments included blood (WBC, Lym, Neu, Eos), lung function (FVC, FEV, PEF), and immunological markers (IgE). ...”This study examines carbon monoxide (CO) emissions and their health effects on individuals with respiratory conditions such as asthma, COPD, and bronchitis. CO sources include biomass burning, industrial processes, and vehicle exhaust, with CO's high hemoglobin affinity impairing oxygen trans...
Få fuldtekst
Article -
87
Lung volumes, gas transfer and oscillometry after preterm birth: systematic review and meta-analysis
Udgivet 2025-05-01“...Differences in lung function were analysed using random-effects meta-analysis to compute the standardised mean difference (SMD). ...”Background Small airway and lung parenchymal abnormalities frequently occur following preterm birth but are commonly missed by spirometry. Static lung volumes, diffusing capacity of the lung for carbon monoxide (DLCO) and oscillometry provide a more precise characterisation of these conditions. We h...
Få fuldtekst
Article -
88
Airway complications after lung transplantation: Perioperative risk factors and clinical outcomes
Udgivet 2025-08-01“...Demographics, pretransplant medications, post-transplant intensive care unit variables, and lung function were compared between recipients who did vs did not develop airway complications. ...”Background: Airway complications after lung transplantation are common and contribute to worse outcomes. There are limited data documenting perioperative risk factors that could be mitigated to reduce risk. Our objectives were to (1) assess the impact of pretransplant disease–modifying medications a...
Få fuldtekst
Article -
89
Medical Rehabilitation of Children With Idiopathic Scoliosis: Monotherapy or Combined Therapy. A Systematic Literature Review
Udgivet 2025-06-01“...Due to the high risk of bias, lung function changes were not assessed. Conclusions. ...”Background. Idiopathic scoliosis is among the most common spinal disorders diagnosed in 1–3% of children and adolescents. Treatment choice is related to disease severity, with a Cobb angle of 20–40°, a corrective brace or physiotherapy can stop its progression. However, insufficient research has s...
Få fuldtekst
Article -
90
Efficacy and safety analysis of montelukast sodium added on azithromycin in the treatment of Mycoplasma pneumoniae pneumonia in children
Udgivet 2025-06-01“...Both groups were treated for 7 days, and lung function, lung compliance, chest CT signal, inflammatory immune status, and side effects were compared before and after treatment.ResultAfter a month of treatment, positive end expiratory pressure (PEEP) levels were lower in the research group compared to the control group’s kids, whereas forced vital capacity (FVC), tidal volume (TV), peak expiratory flow rate (PEF), pulmonary ventilation per minute (MVV), and pulmonary dynamic compliance (Cdyn) levels were greater (p < 0.05). ...”ObjectiveTo evaluate the safety and effectiveness of using montelukast sodium added on azithromycin for the treatment of pediatric Mycoplasma pneumoniae pneumonia (MPP).MethodsRetrospective analysis showed that 122 children with MPP were divided into a control group (61 cases received azithromycin t...
Få fuldtekst
Article -
91
A Case of “Microinvasive Carcinoma of the Bronchus”
Udgivet 2019-01-01“...Fortunately, timely surgical intervention allowed preservation of lung function and the patient is now under close surveillance....”Deciding on a treatment approach for early stage lung cancer (0-1) is sometimes difficult because of uncertainties regarding the depth of tumour invasion and its margins. Even with advanced technology, such as endobronchial ultrasound and autofluorescence bronchoscopy, it is often difficult to be pr...
Få fuldtekst
Article -
92
COMPLEX ESTIMATION OF BRONCHOPULMONARY SYSTEM IN PATIENTS WITH HODGKINS LYMPHOMA
Udgivet 2012-02-01“...Before the treatment an obstructive lung function pattern connected with tumor substrate has been revealed in 38% of cases. ...”One of the important problems with patients with Hodgkin's lymphoma is lung injury, caused both by a tumor effect and the influence of chemoradiotherapy. Before the treatment an obstructive lung function pattern connected with tumor substrate has been revealed in 38% of cases. After chemoradiot...
Få fuldtekst
Article -
93
Breaking new ground in pulmonary fibrosis: Targeting Pathways and Therapeutic Innovations
Udgivet 2025-04-01“...Pulmonary fibrosis (PF), particularly idiopathic pulmonary fibrosis (IPF), is a progressive interstitial lung disease characterized by excessive deposition of extracellular matrix components, leading to irreversible scarring and decline in lung function. Despite advances in understanding its pathogenesis, effective treatments remain limited. ...”Pulmonary fibrosis (PF), particularly idiopathic pulmonary fibrosis (IPF), is a progressive interstitial lung disease characterized by excessive deposition of extracellular matrix components, leading to irreversible scarring and decline in lung function. Despite advances in understanding its pathoge...
Få fuldtekst
Article -
94
Mental Health Changes in Adolescents and Adults With Cystic Fibrosis After Initiation of Elexacaftor/Tezacaftor/Ivacaftor TherapyTake-Home Points
Udgivet 2025-09-01“...Subgroups were defined by age, sex, lung function at baseline, earlier use of any other modulator, and use of psychotropic medications. ...”Background: Starting elexacaftor/tezacaftor/ivacaftor (ETI) is considered a positive life event for people with cystic fibrosis (pwCF). Nevertheless, some individuals report a decline in mental health after commencing ETI. Research Question: How do various mental health indicators of pwCF ≥ 12 years...
Få fuldtekst
Article -
95
Effect of Pharmacological Treatment on Exercise-Induced Bronchoconstriction and Allergic Inflammatory Response in Endurance Athletes
Udgivet 2025-08-01“...At baseline, the O2 peak, lung function, allergic symptoms, IgE, IgA, FeNO levels, and AIR were not significancly different between groups (p>0.05). ...”# Background Endurance athletes (EA) with lung disease and allergic inflammation have worse performance. # Purpose To examine whether pharmacological treatment can reduce airway disorders such as exercise-induced bronchoconstriction (EIB) and allergic inflammatory response (AIR) in EA. # Study Des...
Få fuldtekst
Article -
96
A Systematic Review and Meta-Analysis on the Safety and Efficacy of Rosuvastatin as an Adjunctive Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Udgivet 2025-06-01“...Additionally, it significantly reduced levels of hs-CRP, TNF-α, IL-6, IL-8, NE, and Gal-3.Conclusion: Despite the limited number of studies and potential bias, evidence suggests that rosuvastatin improves lung function and reduces inflammation in AECOPD, underscoring its potential value and emphasizing the need for further high-quality research.Keywords: rosuvastatin, acute exacerbations of chronic obstructive pulmonary disease, meta-analysis, randomised controlled trials...”Wei Wei An, Le Ting Zheng, Fei Dong, Xiao Ning Zhong Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning City, People’s Republic of ChinaCorrespondence: Xiao Ning Zhong, Department of Respiratory and Critical Care Medicine, The F...
Få fuldtekst
Article -
97
Circulating Antimicrobial Peptides as Biomarkers of Inflammation and Airway Dysfunction After Marathon Running
Udgivet 2025-07-01“...Notably, S100A8 levels correlated negatively with lung function parameters, including forced expiratory volume and mid-expiratory flows. ...”Marathon running exerts physical stress and may lead to transient immune dysregulation, increasing susceptibility to airway inflammation and exercise-induced bronchoconstriction (EIB). This study investigated systemic levels of antimicrobial peptides in athletes and their association with EIB. Serum...
Få fuldtekst
Article -
98
SMOKING STATUS AND EFFECTIVENESS OF ANTIHYPERTENSIVE VASODILATING
Udgivet 2013-02-01“...At baseline and after 8 weeks of the treatment, the dynamics of office blood pressure (BP) levels, parameters of 24-hour BP monitoring, and lung function were compared across the subgroups.Results. ...”Aim. To compare antihypertensive effectiveness of carvedilol, nebivolol, and amlodipine in smokers and non-smokers with arterial hypertension (AH).Material and methods. The study included 130 patients with Stage 1–2 AH, aged 30–55 years, who were randomised into three treatment groups: carvedilol (n...
Få fuldtekst
Article -
99
Effectiveness of mechanical vibration-assisted sputum clearance in pediatric pneumonia: a randomized controlled trial with development of an intelligent parameter optimization mode...
Udgivet 2025-06-01“...The proportion of patients showing clinical improvement (defined as “markedly improved” or “improved”) was assessed, along with symptom resolution times, lung function, blood gas parameters, and inflammatory markers, which were measured at baseline and treatment completion. ...”BackgroundSputum retention in pediatric pneumonia hinders recovery. This study evaluated the therapeutic benefits of incorporating mechanical vibration-assisted sputum clearance (MVSC) as an adjunct to standard pharmacological treatment and developed a nomogram to optimize treatment parameters.Metho...
Få fuldtekst
Article -
100
20 years of the Montreal Cystic Fibrosis Related Diabetes Screening Cohort: key insights
Udgivet 2025-05-01“...Results Findings from the MCFC contributed to a better understanding of cystic fibrosis-related diabetes pathophysiology (in particular, the joint roles of reduced insulin secretion and added insulin resistance) and its relationship with lung function. Over the years, we observed a shift towards overweight and obesity among cystic fibrosis patients, along with improved lung function. ...”Introduction The Montreal Cystic Fibrosis Related Diabetes Screening Cohort (MCFC) was established in 2004 to study the prevalence, risk factors and management of cystic fibrosis-related diabetes, a significant extrapulmonary complication of cystic fibrosis with an increasing prevalence due to impro...
Få fuldtekst
Article