Search Results - "Lactate"

Background Taekwondo is a complex martial art that requires speed, balance, agility, and endurance. This study aims to examine the effects of nitrate and L-arginine supplementation on acute aerobic and anaerobic performance, balance, agility, and recovery in elite taekwondo athletes.Method This stud...

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Lactate, traditionally seen as a byproduct of anaerobic metabolism, has gained attention for its dual role in human health. While it is associated with muscle fatigue, lactate also plays a crucial role in various physiological and pathological processes. This review explores lactate’s dual nature as...

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Goal of the study: to detect the correlation between lactate and pyruvate levels and their ratio (LPR) during ischemia/reperfusion with the post-operative increase of troponin I as a marker of myocardial lesion. Materials and methods. The study was performed among the patients undergoing myocardial...

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Goal of the study: to evaluate the capability of pyruvate which is endogenously produced during myocardium anoxia to prevent the post-perfusion cardiac failure in the patients undergoing revasculization surgery with cardiopulmonary bypass. Materials and methods. 56 patients with coronary disease who...

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Metabolic injury to the myocardium during excessive adrenergic stimulation is primarily mediated by overstimulation of β-adrenergic receptors, resulting in a cascade of biochemical and structural changes that lead to myocardial toxicity. Aim. To investigate the effect of an extract derived from c...

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Background: Hyperlactatemia is a common finding in critically ill children and has a strong association with mortality. Lactate clearance (LC) correlates better with mortality than single-point estimation of lactate. This study aimed to evaluate the prognostic value of LC in predicting mortality amo...

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ABSTRACT D‐lactate is an isomeric form of lactate, which is almost undetectable in the circulation in individuals with normal lactate metabolism. Patients diagnosed with the disease human D‐lactate dehydrogenase deficiency present with elevated plasma D‐lactate, causing D‐lactic acidosis, which can...

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Instead of being waste product of metabolism, lactate, has become a key metabolic and signaling molecule in both exercise physiology and tumor biology. Carcinogenic cells produce huge amounts of lactate through the Warburg effect, which is a hallmark of aggressive tumors, increasing acidity in the e...

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Yinghong Chen,1 Hanrong Hu,1 Congwei Wang,1 Junxuan Wu,1 Jie Zan,2 Yuntao Liu3 1Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China; 2School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, People’s...

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Lactate, once regarded as a metabolic byproduct, is now recognized as a critical immunometabolic regulator that shapes immune responses in both physiological and pathological contexts. This review examines how lactate accumulation occurs across diverse disease settings, including cancer, sepsis, and...

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Susu Zhou,1,2 Kai Zhao,1,2 Chunmei Liu,1,2 Hong Luo,3 Jun Shi,4 Chunhong Liu,5 Xiaoming Li,6 Fang Gao,7 Xiangnan Wu,8 Qin Shen,9 Wenhua Yuan,10 Xiaoqing Chai,1,2,* Xin Wei1,2,* 1Department of Anesthesiology, the First Affiliated Hospital of USTC, Division of Life Sciences and...

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Masaaki Hattori,1 Kazuya Yashiro2 1Department of Community Development, Tokai University, Sapporo, Hokkaido, Japan; 2Faculty of Information Technology, Kanagawa Institute of Technology, Atsugi, Kanagawa, JapanCorrespondence: Masaaki Hattori, Department of Community Development, Tokai University, 5-1...

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Glutamate is an excitatory neurotransmitter in the central nervous system (CNS) that mediates synaptic transmission. However, glutamate homeostasis among neural cells is broken in cerebral ischemia. Excessive glutamate triggers <i>N</i>-methyl-<span style="font-variant: small-cap...

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Abstract Resting lactate concentration in venous blood is a commonly used indicator of metabolic disease risk. Regular exercise during pregnancy improves maternal metabolic health; however, it is unknown if maternal exercise regulates resting lactate concentration. We aimed to elucidate the effects...

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Jingjing Zhao,1 Junyu Wang,2,3 Bing Wei,2,3 Yugeng Liu1– 3 1Department of Infectious Disease and Clinical Microbiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100043, People’s Republic of China; 2Emergency Medicine Clinical Research Center, Beijing Chaoyang Hospital, Capital...

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Purpose: is study of adaptation mechanisms of 400 meter’ hurdles-runners to intensive physical loads. Material: in the research 13 - 400 meters’ hurdles-runners and 13 - 400 meters’ runners participated. Results: it was found that physiological cost of sportsmen’s special workability has fragmentary...

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Lactate and glucose of the venous blood were continuously monitored using the Eirus system for intravascular microdialysis with 20 patients operated for complex non-heritable valvular heart disease and ischemic heart disease. The lactate and glucose concentrations, measured by microdialysis techniqu...

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Background: Lactate is often elevated following major pancreatic surgery but the clinical relevance of this it not known. Methods: A retrospective study including 491 consecutive patients undergoing major pancreatic surgery. Lactate upon arrival to post anaesthesia unit (L0), the morning following s...

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